Synthesis of 3-arylindole derivatives from nitroalkane precursors?
RSC Advances Pub Date: 2016-10-03 DOI: 10.1039/C6RA21144E
Abstract
3-Arylindole derivatives were synthesized by Cu(I) catalysed intramolecular Ullmann coupling of 2-bromoarylaminoalkanes. 2-Bromoarylaminoalkanes were synthesized from 2-bromoarylnitroalkanes, which in turn prepared through AlCl3-mediated Friedel–Crafts alkylation of bromo-substituted β-nitrostyrenes and arenes.
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Journal Name：RSC Advances
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CAS no.: 89640-58-4
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