A rule to distinguish diastereomeric bianthrones by 1H NMR?

RSC Advances Pub Date: 2014-01-10 DOI: 10.1039/C3RA47055E

Abstract

Bianthrones have occurred widely in drug and material developments, but the stereochemistry remains in chaos so far due to the meso, racemic, and axis-rotating phenomena. Based on the computational and experimental results, an effective rule to distinguish between cis and trans bianthrones by 1H NMR is concluded, which applies to both homo- and heterobianthrones.

Graphical abstract: A rule to distinguish diastereomeric bianthrones by 1H NMR
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