Enantiomeric helical TiO2 nanofibers modulate different peptide assemblies and subsequent cellular behaviors?
RSC Advances Pub Date: 2019-09-17 DOI: 10.1039/C9RA04660G
Abstract
The effect of the morphological chirality of inorganic TiO2 nanofibers on peptide assembly and cellular behaviors was investigated. Model peptide insulin maintains its native structure and served as a growth factor for promoting proliferation and differentiation of PC12 cells on the surface of right-handed TiO2. In contrast, insulin forms amyloid fibrils and loses its bioactivity on the left-handed TiO2.
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Journal Name：RSC Advances
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CAS no.: 89640-58-4
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