Multicolor GLUT5-permeable fluorescent probes for fructose transport analysis?
Chemical Communications Pub Date: 2018-03-19 DOI: 10.1039/C7CC09809J
Abstract
The specificity of carbohydrate transporters towards their substrates poses a significant challenge for the development of molecular probes to monitor sugar uptake in cells for biochemical and biomedical applications. Herein we report a new set of coumarin-based fluorescent sugar conjugates applicable for the analysis of fructose uptake due to their free passage through the fructose-specific transporter GLUT5. The reported probes cover a broad range of the fluorescence spectrum providing essential tools for the evaluation of fructose transport capacity in live cells.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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