Ionic liquid-supported sulfonyl hydrazine: a useful reagent for traceless synthesis of pyrazoles?

Organic Chemistry Frontiers Pub Date: 2014-05-20 DOI: 10.1039/C4QO00092G

Abstract

Ionic liquid-supported sulfonyl hydrazine has been synthesized and used as a soluble support for the traceless synthesis of highly substituted pyrazoles from two different routes. Various substituted pyrazoles were synthesized in high yields. A key feature of the protocol is an easy and convenient purification process that avoids chromatographic separation of products and thus makes the method eco-friendly and economical.

Graphical abstract: Ionic liquid-supported sulfonyl hydrazine: a useful reagent for traceless synthesis of pyrazoles
Recommended Literature