Iodine-catalyzed formation of substituted 2-aminobenzothiazole derivatives in PEG400?

RSC Advances Pub Date: 2016-08-02 DOI: 10.1039/C6RA15971K

Abstract

An iodine-catalyzed formation of substituted 2-aminobenzothiazole derivatives is herein described using hydrogen peroxide as an oxidant in PEG400. The method enabled an efficient environmentally sound access to this valuable scaffold in moderate to excellent yields under metal-free conditions.

Graphical abstract: Iodine-catalyzed formation of substituted 2-aminobenzothiazole derivatives in PEG400
Recommended Literature