Fluorinated carbohydrates as chemical probes for molecular recognition studies. Current status and perspectives

Chemical Society Reviews Pub Date: 2020-06-10 DOI: 10.1039/C9CS00099B

Abstract

This review provides an extensive summary of the effects of carbohydrate fluorination with regard to changes in physical, chemical and biological properties with respect to regular saccharides. The specific structural, conformational, stability, reactivity and interaction features of fluorinated sugars are described, as well as their applications as probes and in chemical biology.

Graphical abstract: Fluorinated carbohydrates as chemical probes for molecular recognition studies. Current status and perspectives
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