N-acetylarylamines
N-Acetyl Arylamines are a class of organic compounds characterized by the presence of an arylamine group attached to an acetyl group. These molecules are widely used in pharmaceutical and agrochemical industries due to their diverse functional groups, which facilitate various chemical transformations. Structurally, they consist of an amine group (-NH2) linked to an aromatic ring through a carbonyl group (C=O), with an acetyl moiety attached to the nitrogen atom. This unique structure allows for multiple reactive sites and thus can participate in numerous reactions such as nucleophilic substitution, addition, and coupling reactions.
In pharmaceutical applications, N-acetyl arylamines act as precursors or intermediates in the synthesis of drugs targeting various diseases. For instance, they are used in the development of antihypertensive agents, anti-inflammatory medications, and analgesics due to their ability to modulate receptor activity. Additionally, these compounds find utility in agrochemicals where they serve as herbicides or fungicides by interfering with plant growth processes.
Overall, N-acetyl arylamines represent a versatile and valuable class of molecules in both research and industrial settings, offering potential for innovation across multiple sectors.
| Structure | Chemical Name | CAS | MF |
|---|---|---|---|
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N-(5-Formyl-2-thienyl)acetamide | 31167-35-8 | C7H7NO2S |
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5-(Acetylamino)-1,3,4-thiadiazole-2-sulfonyl Chloride | 32873-57-7 | C4H4ClN3O3S2 |
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2-Thiophenecarboxylic acid, 4-(acetylamino)-5-chloro-, methyl ester | 89499-29-6 | C8H8ClNO3S |
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N-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)acetamide | 904326-87-0 | C13H19BN2O3 |
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N-(2-Methylpyridin-4-yl)acetamide | 18085-47-7 | C8H10N2O |
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2-Acetylamino-3-bromo-5-methylpyridine | 142404-83-9 | C8H9BrN2O |
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N-(3-bromopyridin-2-yl)acetamide | 155444-28-3 | C7H7BrN2O |
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2-Acetylamino-4,5-dimethyl pyridine | 179555-37-4 | C9H12N2O |
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Acetamide,N-(3-methyl-5-isothiazolyl)- | 67209-08-9 | C6H8N2OS |
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3-Acetamidopyridine | 5867-45-8 | C7H8N2O |
Related Literature
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Luke L. Lairson,Warren W. Wakarchuk Chem. Commun., 2007, 365-367
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Stephen P. Fletcher,Richard B. C. Jagt,Ben L. Feringa Chem. Commun., 2007, 2578-2580
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Priyambada Nayak,Tanmaya Badapanda,Anil Kumar Singh,Simanchalo Panigrahi RSC Adv., 2017,7, 16319-16331
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Bo Cao,Yin Wei Chem. Commun., 2018,54, 2870-2873
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Muniyandi Sankaralingam,So Hyun Jeon,Yong-Min Lee,Mi Sook Seo,Wonwoo Nam Dalton Trans., 2016,45, 376-383
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