- Imidazolopyrazine compounds as MAPKAPK5 inhibitors useful for the treatment of degenerative and inflammatory diseases and their preparation, World Intellectual Property Organization, , ,
Cas no 957345-28-7 (4-bromo-3-cyclopropyl-1H-pyrazole)
4-bromo-3-cyclopropyl-1H-pyrazole is a synthetic compound with significant potential in pharmaceutical research. Its pyrazole core offers versatile pharmacophoric properties, while the bromo and cyclopropyl substituents confer notable structural stability and electronic effects. This compound is well-suited for the development of novel drug candidates due to its favorable physical and chemical properties.
957345-28-7 structure
Product Name:4-bromo-3-cyclopropyl-1H-pyrazole
CAS No:957345-28-7
MF:C6H7BrN2
MW:187.037180185318
MDL:MFCD16249536
CID:1015722
PubChem ID:51072269
Update Time:2025-06-20
4-bromo-3-cyclopropyl-1H-pyrazole Chemical and Physical Properties
Names and Identifiers
-
- 4-Bromo-5-cyclopropyl-1H-pyrazole
- 4-bromo-3-cyclopropyl-1H-Pyrazole
- 4-Bromo-3-cyclopropyl-1H-pyrazole (ACI)
- F53373
- ALBB-022797
- SY139473
- AKOS025394953
- AKOS010654818
- 4-Bromo-3-cyclopropylpyrazole
- AKOS015998061
- DA-39884
- LS-07047
- DTXSID10679766
- 957345-28-7
- CS-0155390
- Z815438934
- SCHEMBL1674345
- SCHEMBL14810989
- ZZSZXBMYZBRKFP-UHFFFAOYSA-N
- MFCD16249536
- EN300-110189
- 1H-pyrazole, 4-bromo-5-cyclopropyl-
- 4-bromo-3-cyclopropyl-1H-pyrazole
-
- MDL： MFCD16249536
- Inchi： 1S/C6H7BrN2/c7-5-3-8-9-6(5)4-1-2-4/h3-4H,1-2H2,(H,8,9)
- InChI Key： ZZSZXBMYZBRKFP-UHFFFAOYSA-N
- SMILES： BrC1C(C2CC2)=NNC=1
Computed Properties
- Exact Mass: 185.97900
- Monoisotopic Mass: 185.97926g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 2
- Heavy Atom Count: 9
- Rotatable Bond Count: 1
- Complexity: 114
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 1.5
- Topological Polar Surface Area: 28.7?2
Experimental Properties
- PSA: 28.68000
- LogP: 2.04960
4-bromo-3-cyclopropyl-1H-pyrazole Customs Data
- HS CODE：2933199090
- Customs Data：
China Customs Code:
2933199090Overview:
2933199090. Other structurally non fused pyrazole ring compounds. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%
Declaration elements:
Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date
Summary:
2933199090. other compounds containing an unfused pyrazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
4-bromo-3-cyclopropyl-1H-pyrazole Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| CHENG DOU FEI BO YI YAO Technology Co., Ltd. | FD00203-5g |
4-bromo-5-cyclopropyl-1h-pyrazole |
957345-28-7 | 95% | 5g |
$360 | 2023-09-07 | |
| Chemenu | CM188193-5g |
4-Bromo-5-cyclopropyl-1H-pyrazole |
957345-28-7 | 95% | 5g |
$400 | 2021-08-05 | |
| Chemenu | CM188193-10g |
4-Bromo-5-cyclopropyl-1H-pyrazole |
957345-28-7 | 95% | 10g |
$578 | 2021-08-05 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-AD101-1g |
4-bromo-3-cyclopropyl-1H-pyrazole |
957345-28-7 | 95% | 1g |
965.0CNY | 2021-08-04 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-AD101-50mg |
4-bromo-3-cyclopropyl-1H-pyrazole |
957345-28-7 | 95% | 50mg |
121.0CNY | 2021-08-04 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-AD101-200mg |
4-bromo-3-cyclopropyl-1H-pyrazole |
957345-28-7 | 95% | 200mg |
283.0CNY | 2021-08-04 | |
| TRC | B690993-100mg |
4-Bromo-3-cyclopropyl-1H-pyrazole |
957345-28-7 | 100mg |
$ 64.00 | 2023-04-18 | ||
| TRC | B690993-250mg |
4-Bromo-3-cyclopropyl-1H-pyrazole |
957345-28-7 | 250mg |
$ 110.00 | 2023-04-18 | ||
| TRC | B690993-500mg |
4-Bromo-3-cyclopropyl-1H-pyrazole |
957345-28-7 | 500mg |
$ 161.00 | 2023-04-18 | ||
| TRC | B690993-1g |
4-Bromo-3-cyclopropyl-1H-pyrazole |
957345-28-7 | 1g |
$ 190.00 | 2022-06-06 |
4-bromo-3-cyclopropyl-1H-pyrazole Production Method
Production Method 1
Reaction Conditions
1.1 Reagents: Bromine Solvents: Acetic acid ; rt; 10 min, rt
Reference
4-bromo-3-cyclopropyl-1H-pyrazole Raw materials
4-bromo-3-cyclopropyl-1H-pyrazole Preparation Products
4-bromo-3-cyclopropyl-1H-pyrazole Related Literature
-
Raktani Bikshapathi,Sai Prathima Parvathaneni,Vaidya Jayathirtha Rao Green Chem., 2017,19, 4446-4450
-
Bidyut Kumar Kundu,Rinky Singh,Ritudhwaj Tiwari,Debasis Nayak New J. Chem., 2019,43, 4867-4877
-
P. K. Wawrzyniak,M. T. P. Beerepoot,H. J. M. de Groot,F. Buda Phys. Chem. Chem. Phys., 2011,13, 10270-10279
-
Inês S. Albuquerque,Hélia F. Jeremias,Miguel Chaves-Ferreira,Dijana Matak-Vinkovic,Omar Boutureira,Carlos C. Rom?o Chem. Commun., 2015,51, 3993-3996
-
Suji Lee,Min Su Han Chem. Commun., 2021,57, 9450-9453
957345-28-7 (4-bromo-3-cyclopropyl-1H-pyrazole) Related Products
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