- Preparation of 4-pyrrolo[2,3-c]pyridin-3-yl)-pyrimidin-2-ylamines as antitumor agents, World Intellectual Property Organization, , ,
Cas no 956003-24-0 (3-Iodo-1H-pyrrolo[2,3-c]pyridine)
3-Iodo-1H-pyrrolo[2,3-c]pyridine is a heterocyclic compound featuring an iodine substituent at the 3-position of the pyrrolopyridine core. This structure serves as a versatile intermediate in organic synthesis, particularly in cross-coupling reactions such as Suzuki-Miyaura and Sonogashira couplings, enabling the introduction of diverse functional groups. Its electron-rich aromatic system enhances reactivity in electrophilic substitutions, while the iodine atom provides a handle for further derivatization. The compound is valuable in pharmaceutical and agrochemical research, where it aids in the development of bioactive molecules. High purity and stability under standard conditions make it suitable for precise synthetic applications. Proper handling is recommended due to its sensitivity to light and moisture.
![3-Iodo-1H-pyrrolo[2,3-c]pyridine structure](https://ossimg.kuujia.com/scimg/956500/956003-24-0x500.png)
956003-24-0 structure
Product Name:3-Iodo-1H-pyrrolo[2,3-c]pyridine
CAS No:956003-24-0
MF:C7H5IN2
MW:244.032473325729
MDL:MFCD10699183
CID:837905
PubChem ID:37818505
Update Time:2025-05-22
3-Iodo-1H-pyrrolo[2,3-c]pyridine Chemical and Physical Properties
Names and Identifiers
-
- 3-Iodo-1H-pyrrolo[2,3-c]pyridine
- 1H-Pyrrolo[2,3-c]pyridine, 3-iodo
- 3-Iodo-6-azaindole
- 1H-Pyrrolo[2,3-c]pyridine, 3-iodo-
- KSC494G0J
- HIN1527
- JCBUTJANQMHZJJ-UHFFFAOYSA-N
- BCP08933
- WT1420
- 3-iodo-1h-pyrrolo-[2,3-c]pyridine
- FCH1401116
- 3-iodanyl-1H-pyrrolo[2,3-c]pyridine
- SY097498
- ST2410740
- AX8215841
- AB0037550
- Y4841
- A845343
- 003I240
- 3-Iodo-1H-pyrrolo[2,3-c]pyridine (ACI)
- CS-0041505
- AKOS015853765
- SB40300
- DTXSID50653282
- J-512675
- EN300-1699504
- SCHEMBL245511
- DS-15652
- MFCD10699183
- Z1269236830
- 956003-24-0
-
- MDL： MFCD10699183
- Inchi： 1S/C7H5IN2/c8-6-3-10-7-4-9-2-1-5(6)7/h1-4,10H
- InChI Key： JCBUTJANQMHZJJ-UHFFFAOYSA-N
- SMILES： IC1C2C(=CN=CC=2)NC=1
Computed Properties
- Exact Mass: 243.95
- Monoisotopic Mass: 243.95
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 1
- Heavy Atom Count: 10
- Rotatable Bond Count: 0
- Complexity: 129
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 28.7
- XLogP3: 1.6
Experimental Properties
- Density: 2.082
- Boiling Point: 380.5°C at 760 mmHg
- Flash Point: 183.9°C
- Refractive Index: 1.787
3-Iodo-1H-pyrrolo[2,3-c]pyridine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Fluorochem | 211836-250mg |
3-Iodo-1H-pyrrolo[2,3-c]pyridine |
956003-24-0 | 95% | 250mg |
￡21.00 | 2022-03-01 | |
| Fluorochem | 211836-1g |
3-Iodo-1H-pyrrolo[2,3-c]pyridine |
956003-24-0 | 95% | 1g |
￡54.00 | 2022-03-01 | |
| Fluorochem | 211836-5g |
3-Iodo-1H-pyrrolo[2,3-c]pyridine |
956003-24-0 | 95% | 5g |
￡161.00 | 2022-03-01 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | I178529-5g |
3-Iodo-1H-pyrrolo[2,3-c]pyridine |
956003-24-0 | 97% | 5g |
￥1067.90 | 2023-09-02 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | I178529-1g |
3-Iodo-1H-pyrrolo[2,3-c]pyridine |
956003-24-0 | 97% | 1g |
￥256.90 | 2023-09-02 | |
| Chemenu | CM149450-1g |
3-Iodo-1H-pyrrolo[2,3-c]pyridine |
956003-24-0 | 95%+ | 1g |
$70 | 2021-08-05 | |
| Chemenu | CM149450-5g |
3-Iodo-1H-pyrrolo[2,3-c]pyridine |
956003-24-0 | 95%+ | 5g |
$282 | 2021-08-05 | |
| Matrix Scientific | 069079-500mg |
3-Iodo-1H-pyrrolo[2,3-c]pyridine, 98% |
956003-24-0 | 98% | 500mg |
$719.00 | 2023-09-08 | |
| Matrix Scientific | 069079-1g |
3-Iodo-1H-pyrrolo[2,3-c]pyridine, 98% |
956003-24-0 | 98% | 1g |
$1393.00 | 2023-09-08 | |
| CHENG DOU FEI BO YI YAO Technology Co., Ltd. | FC11642-25g |
3-iodo-1H-pyrrolo[2,3-c]pyridine |
956003-24-0 | 98% | 25g |
$350 | 2023-09-07 |
3-Iodo-1H-pyrrolo[2,3-c]pyridine Production Method
Production Method 1
Reaction Conditions
1.1 Reagents: Potassium hydroxide , Iodine Solvents: Dimethylformamide ; rt; 45 min, rt
Reference
Production Method 2
Reaction Conditions
1.1 Reagents: Potassium hydroxide , Iodine Solvents: Dimethylformamide ; rt; 30 min, rt
Reference
- Preparation of dibenzo[b,e][1,4]diazepin-11-ones as kinase inhibitors for treatment of cancer, United States, , ,
Production Method 3
Reaction Conditions
1.1 Reagents: Potassium hydroxide , Iodine Solvents: Dimethylformamide ; rt; 45 min, rt
1.2 Reagents: Ammonium hydroxide , Sodium pyrosulfite Solvents: Water ; cooled
1.2 Reagents: Ammonium hydroxide , Sodium pyrosulfite Solvents: Water ; cooled
Reference
- Rapid preparation of triazolyl substituted NH-heterocyclic kinase inhibitors via one-pot Sonogashira coupling-TMS-deprotection-CuAAC sequenceMerkul, Eugen; Klukas, Fabian; Dorsch, Dieter; Graedler, Ulrich; Greiner, Hartmut E.; et al, Organic & Biomolecular Chemistry, 2011, 9(14), 5129-5136
Production Method 4
Reaction Conditions
1.1 Reagents: N-Iodosuccinimide Solvents: Acetonitrile ; 1.5 h, rt
Reference
- Developing DYRK inhibitors derived from the meridianins as a means of increasing levels of NFAT in the nucleusShaw, Simon J.; Goff, Dane A.; Lin, Nan; Singh, Rajinder; Li, Wei; et al, Bioorganic & Medicinal Chemistry Letters, 2017, 27(11), 2617-2621
Production Method 5
Reaction Conditions
Reference
- Preparation of 4-pyrrolo[2,3-c]pyridin-3-yl)-pyrimidin-2-ylamines as antitumor agents, Germany, , ,
3-Iodo-1H-pyrrolo[2,3-c]pyridine Raw materials
3-Iodo-1H-pyrrolo[2,3-c]pyridine Preparation Products
3-Iodo-1H-pyrrolo[2,3-c]pyridine Related Literature
-
Hongxia Li,Aikifa Raza,Qiaoyu Ge,Jin-You Lu,TieJun Zhang Soft Matter, 2020,16, 6841-6849
-
J. Xu,T. J. Carrocci,A. A. Hoskins Chem. Commun., 2016,52, 549-552
-
3. Fe3O4/Au/Fe3O4 nanoflowers exhibiting tunable saturation magnetization and enhanced bioconjugationFeng Shi,Kunping Yan,Mingli Peng,Xiao Cheng,Yanling Luo,Xuemei Chen,V. A. L. Roy,Zuankai Wang Nanoscale, 2012,4, 747-751
-
Qiaoe Wang,Meiling Lian,Xiaowen Zhu,Xu Chen RSC Adv., 2021,11, 192-197
-
Zhiyan Chen,Nan Wu,Yaobing Wang,Bing Wang,Yingde Wang J. Mater. Chem. A, 2018,6, 516-526
956003-24-0 (3-Iodo-1H-pyrrolo[2,3-c]pyridine) Related Products
- 79476-07-6(3-Iodoquinoline)
- 89976-15-8(7-Iodo-1H-indole)
- 1228666-28-1(3-Iodo-1,5-naphthyridine)
- 1083181-26-3(3-Iodo-1H-pyrrolo[3,2-b]pyridine)
- 81038-38-2(4-Iodo-1H-indole)
- 877060-47-4(3-Iodo-1H-pyrrolo[3,2-C]pyridine)
- 26340-47-6(3-Iodoindole)
- 16560-43-3(4-Iodoquinoline)
- 1006-50-4(5-Iodoquinoline)
- 1006-47-9(8-Iodoquinoline)
Recommended suppliers
Inner Mongolia Xinhong Biological Technology Co., Ltd
Gold Member
Audited Supplier
CN Supplier
Bulk
鉅瀾化工科技(青島)有限公司
Gold Member
Audited Supplier
CN Supplier
Bulk
Shanghai Pearlk Chemicals Co., Ltd.
Gold Member
Audited Supplier
CN Supplier
Bulk
Shandong Jing Kun Chemical Co.,Ltd.
Gold Member
Audited Supplier
CN Supplier
Bulk
Shanghai Hongxiang Biomedical Technology Co., Ltd.
Gold Member
Audited Supplier
CN Supplier
Bulk
