Pyrrolopyridines
Pyrrolopyridines are a class of heterocyclic organic compounds characterized by the fusion of pyrrole and pyridine rings. These molecules exhibit diverse structural features, making them versatile in various applications across multiple fields such as pharmaceuticals, agrochemicals, and materials science. Their unique electronic properties stem from the conjugated systems present within their structure, which can lead to interesting biological activities.
In drug discovery, pyrrolopyridines have shown promise as potential therapeutic agents due to their ability to modulate specific protein targets such as kinases and GPCRs (G-protein coupled receptors). The pharmacological potential of these compounds is often attributed to their functional groups, which can be easily modified for optimization. Additionally, the chemical diversity arising from different substituents allows for a wide range of possible structures, facilitating the exploration of new leads in medicinal chemistry.
In agricultural applications, pyrrolopyridines have been investigated as herbicides and fungicides due to their selective toxicity towards specific organisms. Their structure-activity relationships provide insights into designing more effective agrochemicals with reduced environmental impact.
Overall, pyrrolopyridines represent a promising area of research in organic chemistry, offering numerous opportunities for innovation across various industries.
| Structure | Chemical Name | CAS | MF |
|---|---|---|---|
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N-Allyl-1,7-dideazaadenine | 640735-22-4 | C10H11N3 |
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1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one | 736990-65-1 | C7H8N2O |
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1H-Pyrrolo[2,3-c]pyridine, 7-chloro-2,3-dimethyl- | 874013-98-6 | C9H9ClN2 |
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1H-Pyrrolo[2,3-b]pyridine,5-methoxy-2-methyl- | 397842-91-0 | C9H10N2O |
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2-benzyl-octahydro-1H-pyrrolo[3,4-c]pyridine | 351370-98-4 | C14H20N2 |
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5-methoxy-1H-pyrrolo[2,3-b]pyridine | 183208-36-8 | C8H8N2O |
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1-(2-Bromoethyl)-1H-pyrrolo[2,3-b]pyridine | 183208-58-4 | C9H9BrN2 |
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6-Chloro-1H-pyrrolo[2,3-B]pyridine | 55052-27-2 | C7H5ClN2 |
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3-chloro-1H-pyrrolo[2,3-b]pyridine | 80235-01-4 | C7H5ClN2 |
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4-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde | 918515-16-9 | C8H5ClN2O |
Related Literature
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Guang Xu,Wei Zhang,Ying Zhang,Xiaoxia Zhao,Ping Wen,Di Ma RSC Adv., 2018,8, 19353-19361
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Gaurav J. Shah,Eric P.-Y. Chiou,Ming C. Wu,Chang-Jin “CJ” Kim Lab Chip, 2009,9, 1732-1739
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Alena Koukalová,?árka Pokorná,Aimee L. Boyle,Nestor Lopez Mora,Alexander Kros,Martin Hof,Radek ?achl Nanoscale, 2018,10, 19064-19073
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Joseph W. Bennett,Diamond T. Jones,Blake G. Hudson,Joshua Melendez-Rivera,Robert J. Hamers,Sara E. Mason Environ. Sci.: Nano, 2020,7, 1642-1651
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