- Cobalt catalyzed chemoselective reduction of nitroarenes: hydrosilylation under thermal and photochemical reaction conditionsPanda, Surajit; Nanda, Amareshwar; Behera, Rakesh R.; Ghosh, Rahul; Bagh, Bidraha, Chemical Communications (Cambridge, 2023, 59(30), 4527-4530
Cas no 95-68-1 (2,4-dimethylaniline)
2,4-Dimethylaniline is an aromatic amine with the molecular formula C?H??N, featuring two methyl groups at the 2- and 4-positions of the aniline ring. This compound is commonly utilized as an intermediate in the synthesis of dyes, pigments, and agrochemicals due to its reactive amino group and stable aromatic structure. Its methyl substitutions enhance steric and electronic properties, making it valuable for tailored chemical modifications. The product is typically supplied as a clear to pale yellow liquid with moderate solubility in organic solvents. Proper handling is essential, as it may pose health hazards, including toxicity and potential skin irritation. Storage under inert conditions is recommended to prevent oxidation.
2,4-dimethylaniline structure
Product Name:2,4-dimethylaniline
CAS No:95-68-1
MF:C8H11N
MW:121.179641962051
MDL:MFCD00007738
CID:34809
PubChem ID:7250
Update Time:2025-06-07
2,4-dimethylaniline Chemical and Physical Properties
Names and Identifiers
-
- 2,4-Dimethylbenzenamine
- 2,4-Xylidine
- 2,4-Dimethylaniline
- m-Xylidine
- 1-Amino-2,4-dimethylbenzene
- 2,4-Dimethyl aminobenzene
- 2,4-Dimethylbenzenamine (ACI)
- 2,4-Xylidine (8CI)
- 2,4-Dimethylphenylamine
- 2,4-Xylylamine
- 4-Amino-1,3-dimethylbenzene
- 4-Amino-1,3-xylene
- NSC 7640
- Amitraz Imp. A (BP): 2,4-Dimethylaniline (2,4-Xylidine)
- 2,4-dimethylaniline
-
- MDL: MFCD00007738
- Inchi: 1S/C8H11N/c1-6-3-4-8(9)7(2)5-6/h3-5H,9H2,1-2H3
- InChI Key: CZZZABOKJQXEBO-UHFFFAOYSA-N
- SMILES: NC1C(C)=CC(C)=CC=1
- BRN: 636243
Computed Properties
- Exact Mass: 121.08900
- Monoisotopic Mass: 121.089
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 1
- Heavy Atom Count: 9
- Rotatable Bond Count: 0
- Complexity: 90.6
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- Tautomer Count: nothing
- XLogP3: nothing
- Topological Polar Surface Area: 26A^2
Experimental Properties
- Color/Form: Colorless oily liquid [1]
- Density: 0.98?g/mL?at 25?°C(lit.)
- Melting Point: ?14.3?°C (lit.)
- Boiling Point: 218?°C(lit.)
- Flash Point: Fahrenheit: 208.4 ° f
Celsius: 98 ° c - Refractive Index: n20/D 1.558(lit.)
- PH: 7 (22g/l, H2O, 20℃)
- Solubility: 5g/l
- Water Partition Coefficient: 5 g/L (20 oC)
- Stability/Shelf Life: Stable. Combustible. Incompatible with strong oxidizing agents, acids, acid anhydrides, acid chlorides, chloroformates, halogens.
- PSA: 26.02000
- LogP: 2.46680
- Merck: 10084
- Vapor Pressure: 0.16 mmHg ( 25 °C)
- FEMA: 3596
- Sensitiveness: Sensitive to light
- Solubility: Slightly soluble in water, soluble in ethanol, ether, benzene and other organic solvents. [12]
2,4-dimethylaniline Security Information
-
Symbol:
- Prompt:dangerous
- Signal Word:Danger
- Hazard Statement: H301,H311,H331,H373,H411
- Warning Statement: P261,P273,P280,P301+P310,P311
- Hazardous Material transportation number:UN 1711 6.1/PG 2
- WGK Germany:2
- Hazard Category Code: 23/24/25-33-51/53
- Safety Instruction: S28-S36/37-S45-S61-S28A
- FLUKA BRAND F CODES:8
- RTECS:ZE8925000
-
Hazardous Material Identification:
- Safety Term:6.1
- Packing Group:II
- Risk Phrases:R23/24/25; R33; R51/53
- HazardClass:6.1
- PackingGroup:II
- TSCA:Yes
- Explosive Limit:1.1-7.0%(V)
- Storage Condition:room temp
2,4-dimethylaniline Customs Data
- HS CODE:2921419000
- Customs Data:
China Customs Code:
2921419000Overview:
HS:2921419000 Aniline salt VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:6.5% general tariff:30.0%
Declaration elements:
Product Name, component content, use to
Summary:
2921419000 aniline and its salts.Supervision conditions:None.VAT:17.0%.Tax rebate rate:9.0%.MFN tariff:6.5%.General tariff:30.0%
2,4-dimethylaniline Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | D0667-25ml |
2,4-dimethylaniline |
95-68-1 | 98.0%(GC&T) | 25ml |
¥165.0 | 2022-05-30 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | D0667-500ml |
2,4-dimethylaniline |
95-68-1 | 98.0%(GC&T) | 500ml |
¥725.0 | 2022-05-30 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | D090A-100g |
2,4-dimethylaniline |
95-68-1 | 99% | 100g |
¥107.0 | 2022-05-30 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | D090A-500g |
2,4-dimethylaniline |
95-68-1 | 99% | 500g |
¥245.0 | 2022-05-30 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | D105631-500mg |
2,4-dimethylaniline |
95-68-1 | 500mg |
¥313.90 | 2023-09-03 | ||
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | D105632-100ml |
2,4-dimethylaniline |
95-68-1 | 99% | 100ml |
¥95.90 | 2023-09-03 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | D105632-25ml |
2,4-dimethylaniline |
95-68-1 | 99% | 25ml |
¥41.90 | 2023-09-03 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | D105632-10l |
2,4-dimethylaniline |
95-68-1 | 99% | 10l |
¥4094.90 | 2023-09-03 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | D105632-2.5L |
2,4-dimethylaniline |
95-68-1 | 99% | 2.5l |
¥1331.90 | 2023-09-03 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | D105632-20l |
2,4-dimethylaniline |
95-68-1 | 99% | 20l |
¥5774.90 | 2023-09-03 |
2,4-dimethylaniline Production Method
Production Method 1
Reaction Conditions
1.1 Reagents: Phenylsilane Catalysts: Dicobalt octacarbonyl Solvents: Tetrahydrofuran ; 3 h, 100 °C
Reference
Production Method 2
Reaction Conditions
1.1 Reagents: 2-Propanone, O-[(2,4,6-trimethylphenyl)sulfonyl]oxime Catalysts: Cuprous cyanide Solvents: Tetrahydrofuran ; 1.5 h, rt
1.2 Reagents: Hydrochloric acid Solvents: Water ; overnight, rt
1.3 Reagents: Sodium hydroxide Solvents: Water ; basified, rt
1.2 Reagents: Hydrochloric acid Solvents: Water ; overnight, rt
1.3 Reagents: Sodium hydroxide Solvents: Water ; basified, rt
Reference
- Electrophilic amination of diarylcadmium reagents: the effect of aminating reagent's structureDaskapan, Tahir ; Korkmaz, Adem, Journal of Chemical Sciences (Berlin, 2022, 134(4),
Production Method 3
Reaction Conditions
1.1 Reagents: Hydrogen Catalysts: Cobalt Solvents: Ethanol , Methanol ; 2 h, 2 MPa, 60 °C
Reference
- In situ-formed cobalt nanoparticles embedded within carbonaceous matrix as highly efficient and selective catalysts for the hydrogenation of nitroarenesZhuang, Xiuzheng; Liu, Jianguo; Zhong, Shurong; Ma, Longlong, Sustainable Chemistry and Pharmacy, 2022, 29,
Production Method 4
Reaction Conditions
1.1 Reagents: Hydrazine hydrate (1:1) Catalysts: Molybdenum nitride (Mo2N) Solvents: Ethanol ; 1 h, 30 °C
Reference
- Mo2N as a high-efficiency catalyst for transfer hydrogenation of nitrobenzene using stoichiometric hydrazine hydrateLuo, Shicheng; Long, Yu; Liang, Kun; Sun, Xun; Qin, Jiaheng; et al, Molecular Catalysis, 2022, 531,
Production Method 5
Reaction Conditions
1.1 Reagents: Ammonia , Tripotassium phosphate Catalysts: Copper , 2633071-98-2 Solvents: Dimethyl sulfoxide , Water ; 48 h, 80 °C
Reference
- Porous polymeric ligand promoted copper-catalyzed C-N coupling of (hetero)aryl chlorides under visible-light irradiationWang, Erfei; Chen, Kaixuan; Chen, Yinan; Zhang, Jiawei; Lin, Xinrong; et al, Science China: Chemistry, 2021, 64(1), 17-21
Production Method 6
Reaction Conditions
1.1 Reagents: Oxygen , Hydrazine hydrate (1:1) Catalysts: Molybdenum nitrogen oxide , Carbon nitride (C3N4) Solvents: Ethanol ; 1 h, 30 °C
Reference
- Unsaturated Mo in Mo4O4N3 for efficient catalytic transfer hydrogenation of nitrobenzene using stoichiometric hydrazine hydrateLuo, Shicheng; Long, Yu; Liang, Kun; Qin, Jiaheng; Qiao, Yi; et al, Green Chemistry, 2021, 23(21), 8545-8553
Production Method 7
Reaction Conditions
1.1 Reagents: Hydrogen Catalysts: Carbon Solvents: Methanol , Water ; 3 h, 5 bar, 90 °C
Reference
- Co,N-Codoped Porous Carbon-Supported CoyZnS with Superior Activity for Nitroarene HydrogenationZhang, Guangji; Tang, Feiying; Wang, Xiaoying; An, Ping; Wang, Liqiang ; et al, ACS Sustainable Chemistry & Engineering, 2020, 8(15), 6118-6126
Production Method 8
Reaction Conditions
1.1 Reagents: Hydrogen Catalysts: Potassium tert-butoxide , Manganese, bromodicarbonyl[6-[(diphenylphosphino-κP)methyl]-2,2′-bipyridine-κN1,… Solvents: Toluene ; 48 h, 20 bar, 130 °C; 130 °C → 0 °C; 30 min, 0 °C
Reference
- Manganese Catalyzed Hydrogenation of Carbamates and Urea DerivativesDas, Uttam Kumar ; Kumar, Amit; Ben-David, Yehoshoa; Iron, Mark A. ; Milstein, David, Journal of the American Chemical Society, 2019, 141(33), 12962-12966
Production Method 9
Reaction Conditions
1.1 Reagents: Hydrogen Catalysts: Palladium Solvents: Ethanol ; 1.25 h, 1 atm, rt
Reference
- Green reusable Pd nanoparticles embedded in phytochemical resins for mild hydrogenations of nitroarenesEnneiymy, Mohamed; Le Drian, Claude; Becht, Jean-Michel, New Journal of Chemistry, 2019, 43(44), 17383-17389
Production Method 10
Reaction Conditions
1.1 Reagents: Hydrazine hydrate (1:1) Catalysts: Cobalt oxide (titanium oxide supported) Solvents: Ethanol ; 24 h
Reference
- Photocatalytic hydrogenation of nitroarenes: supporting effect of CoOx on TiO2 nanoparticlesAmanchi, Srinivasa Rao; Ashok Kumar, K. V.; Lakshminarayana, Bhairi; Satyanarayana, G.; Subrahmanyam, Ch., New Journal of Chemistry, 2019, 43(2), 748-754
Production Method 11
Reaction Conditions
1.1 Reagents: Lithium hydroxide , Hydrazine hydrate (1:1) Catalysts: Palladium Solvents: 1,4-Dioxane ; 20 min, rt; 16 h, 170 °C
Reference
- Direct conversion of phenols into primary anilines with hydrazine catalyzed by palladiumQiu, Zihang; Lv, Leiyang; Li, Jianbin; Li, Chen-Chen; Li, Chao-Jun, Chemical Science, 2019, 10(18), 4775-4781
Production Method 12
Reaction Conditions
1.1 Reagents: Formic acid , Triethylamine Catalysts: Ruthenium, [(1,2,5,6-η)-1,5-cyclooctadiene]bis[(1,2,3-η)-2-methyl-2-propenyl]- , Triphos , Bis(trifluoromethanesulfonyl)imide Solvents: Butyl ether ; 24 h, 130 °C
Reference
- Ru-Catalyzed Deoxygenative Transfer Hydrogenation of Amides to Amines with Formic acid/TriethylaminePan, Yixiao; Luo, Zhenli; Xu, Xin; Zhao, Haoqiang; Han, Jiahong; et al, Advanced Synthesis & Catalysis, 2019, 361(16), 3800-3806
Production Method 13
Reaction Conditions
1.1 Reagents: Hydrogen Catalysts: Palladium Solvents: Dimethylformamide ; 8 h, 0.6 MPa, 120 °C
Reference
- Solvent-Driven Selectivity Control to Either Anilines or Dicyclohexylamines in Hydrogenation of Nitroarenes over a Bifunctional Pd/MIL-101 CatalystChen, Xiaodong; Shen, Kui ; Ding, Danni; Chen, Junying; Fan, Ting ; et al, ACS Catalysis, 2018, 8(11), 10641-10648
Production Method 14
Reaction Conditions
1.1 Reagents: Hydrazine hydrate (1:1) Catalysts: Molybdenum oxide (MoO3) (cobalt and N-doped graphite, supported on SBA-15) , Cobalt (molybdenum oxide and N-doped graphitic carbon, supported on SBA-15) , Silica Solvents: Ethanol ; 60 min, 30 °C
Reference
- N-doped graphitic carbon-improved Co-MoO3 catalysts on ordered mesoporous SBA-15 for chemoselective reduction of nitroarenesHuang, Haigen; Liang, Xiangcheng; Wang, Xueguang; Sheng, Yao; Chen, Chenju; et al, Applied Catalysis, 2018, 559, 127-137
Production Method 15
Reaction Conditions
1.1 Reagents: Hydrogen Catalysts: Nickel Solvents: Water ; 2.5 h, 5 MPa, 100 °C
Reference
- Nitrogen-doped graphene-activated metallic nanoparticle-incorporated ordered mesoporous carbon nanocomposites for the hydrogenation of nitroarenesHuang, Haigen; Wang, Xueguang; Sheng, Yao; Chen, Chenju; Zou, Xiujing; et al, RSC Advances, 2018, 8(16), 8898-8909
Production Method 16
Reaction Conditions
1.1 Reagents: Hydrogen , Hydrazine hydrate (1:1) Catalysts: Hexadecyl-3-methylimidazolium bromide (Ruthenium supported) Solvents: Ethanol ; 2 h, 2 MPa, 40 °C
Reference
- Preparation of Well-Ordered Mesoporous-Silica-Supported Ruthenium Nanoparticles for Highly Selective Reduction of Functionalized Nitroarenes through Transfer HydrogenationWei, Ning; Zou, Xiujing; Huang, Haigen; Wang, Xueguang; Ding, Weizhong; et al, European Journal of Organic Chemistry, 2018, 2018(2), 209-214
Production Method 17
Reaction Conditions
1.1 Reagents: Sodium hydride Catalysts: Titania Solvents: Tetrahydrofuran ; 1 h, rt
Reference
- TiO2-Nanoparticles Catalyzed Synthesis of New Trifluoromethyl-4,5-dihydro-1,2,4-oxadiazoles and Trifluoromethyl-1,2,4-oxadiazolesDarehkordi, Ali ; Ramezani, Mahin; Rahmani, Fariba, Journal of Heterocyclic Chemistry, 2018, 55(7), 1702-1708
Production Method 18
Reaction Conditions
1.1 Reagents: Hydrazine hydrate (1:1) Catalysts: Molybdenum oxide (MoO3) (NiO/SBA-15 supported) , Nickel monoxide (MoO3/SBA-15 supported) Solvents: Ethanol ; 30 min, 40 °C
Reference
- Highly chemoselective reduction of nitroarenes over non-noble metal nickel-molybdenum oxide catalystsHuang, Haigen; Wang, Xueguang; Li, Xu; Chen, Chenju; Zou, Xiujing; et al, Green Chemistry, 2017, 19(3), 809-815
Production Method 19
Reaction Conditions
1.1 Reagents: Tris(pentafluorophenyl)borane , Hydrogen Catalysts: Sodium tetrakis[3,5-bis(trifluoromethyl)phenyl]borate , (SP-5-43)-[2,6-Bis[[bis(1-methylethyl)phosphino-κP]oxy]phenyl-κC]chlorohydroirid… Solvents: Toluene ; 24 h, 50 atm, 120 °C
Reference
- Deoxygenative Hydrogenation of Amides Catalyzed by a Well-Defined Iridium Pincer ComplexYuan, Ming-Lei; Xie, Jian-Hua; Zhu, Shou-Fei; Zhou, Qi-Lin, ACS Catalysis, 2016, 6(6), 3665-3669
Production Method 20
Reaction Conditions
1.1 Reagents: Sodium borohydride Catalysts: Nickel , Silica Solvents: Water ; 65 min, rt
Reference
- Preparation and characterization of Ni/mZSM-5 zeolite with a hierarchical pore structure by using KIT-6 as silica template: an efficient bi-functional catalyst for the reduction of nitro aromatic compoundsMazaheri, Omid; Kalbasi, Roozbeh Javad, RSC Advances, 2015, 5(43), 34398-34414
Production Method 21
Reaction Conditions
Reference
- Hydroxylamine-mediated C-C amination via an aza-hock rearrangementWang, Tao; Stein, Philipp M.; Shi, Hongwei; Hu, Chao; Rudolph, Matthias; et al, Nature Communications, 2021, 12(1),
Production Method 22
Reaction Conditions
1.1 Reagents: Sodium borohydride Catalysts: Ruthenium Solvents: Ethanol , Water ; 240 min, rt
Reference
- A One-Step Method for Preparation of Ru Nanoparticle Decorated on Three-Dimensional Graphene with High Catalytic Activity for Reduction of NitroarenesDabiri, Minoo; Miraghaee, Seyedesahar; Nikbakht, Roonak; Bashiribod, Sahareh, Journal of Cluster Science, 2021, 32(4), 959-965
Production Method 23
Reaction Conditions
1.1 Reagents: Phenylsilane Catalysts: Triphenylphosphine , Sodium iodide Solvents: Chloroform ; 72 h, 60 °C
1.2 Reagents: Sodium carbonate Solvents: Water
1.2 Reagents: Sodium carbonate Solvents: Water
Reference
- NaI/PPh3-Mediated Photochemical Reduction and Amination of NitroarenesQu, Zhonghua; Chen, Xing; Zhong, Shuai; Deng, Guo-Jun ; Huang, Huawen, Organic Letters, 2021, 23(14), 5349-5353
Production Method 24
Reaction Conditions
1.1 Reagents: Hydroxyamine hydrochloride , Sulfuric acid Solvents: Acetonitrile ; 25 °C; 10 min, 25 °C
1.2 Reagents: Hydrochloric acid , Titanium chloride (TiCl3) Solvents: Water ; 25 °C; 10 min, 25 °C
1.3 Reagents: Citric acid, sodium salt , Sodium hydroxide Solvents: Water ; basified, 25 °C
1.2 Reagents: Hydrochloric acid , Titanium chloride (TiCl3) Solvents: Water ; 25 °C; 10 min, 25 °C
1.3 Reagents: Citric acid, sodium salt , Sodium hydroxide Solvents: Water ; basified, 25 °C
Reference
- C-H Amination of Arenes with HydroxylamineSee, Yi Yang; Sanford, Melanie S., Organic Letters, 2020, 22(8), 2931-2934
Production Method 25
Reaction Conditions
1.1 Reagents: Hydrogen Catalysts: Palladium Solvents: Ethanol ; 2 h, 1 atm, rt
Reference
- Palladium nanoparticles embedded in mesoporous carbons as efficient, green and reusable catalysts for mild hydrogenations of nitroarenesEnneiymy, Mohamed; Fioux, Philippe; Le Drian, Claude; Matei Ghimbeu, Camelia; Becht, Jean-Michel, RSC Advances, 2020, 10(60), 36741-36750
Production Method 26
Reaction Conditions
1.1 Reagents: Potassium carbonate , Sulfur , Water Solvents: Dimethylformamide ; 20 h, 150 °C
Reference
- Metal-free chemoselective reduction of nitroaromatics to anilines via hydrogen transfer strategyShuai, Qi; Li, Jun; Zhao, Feng; Su, Weike ; Deng, Guojun, Chemical Papers, 2019, 73(4), 965-975
Production Method 27
Reaction Conditions
1.1 Reagents: Sodium hydroxide ; 10 min, 80 °C
Reference
- Chromogenic spray reagent for the detection and identifi cation of amitraz in biological materialsMulani, Khudbudin B.; Kamble, Brahmanand M.; Chandegaonkar, Vijay R.; Deshpande, Hemantini A., Journal of Planar Chromatography--Modern TLC, 2019, 32(1), 51-53
Production Method 28
Reaction Conditions
1.1 Catalysts: Iron , Copper , Cellulose Solvents: Water ; 5 min, rt
1.2 Reagents: Sodium borohydride ; 7 h, 70 °C
1.2 Reagents: Sodium borohydride ; 7 h, 70 °C
Reference
- Cellulose supported bimetallic Fe-Cu nanoparticles: a magnetically recoverable nanocatalyst for quick reduction of nitroarenes to amines in waterKarami, Shiva; Zeynizadeh, Behzad; Shokri, Zahra, Cellulose (Dordrecht, 2018, 25(6), 3295-3305
Production Method 29
Reaction Conditions
1.1 Reagents: Ammonium formate Catalysts: Palladium Solvents: Ethanol ; 12 h, rt
Reference
- Highly efficient reduction of nitro compounds: recyclable Pd/C-catalyzed transfer hydrogenation with ammonium formate or hydrazine hydrate as hydrogen sourceChen, Xia; Zhou, Xiao-Yu; Wu, Hong; Lei, Yi-Zhu; Li, Jin-Hui, Synthetic Communications, 2018, 48(19), 2475-2484
Production Method 30
Reaction Conditions
Reference
- Synthesis, characterization, anticancer and antifungal studies of Pyrazole carboxamide derivativesSa, Adinarayana; Chauhana, Pramod K.; Choudhary, Prakash C., Chemistry & Biology Interface, 2018, 8(1), 26-44
Production Method 31
Reaction Conditions
Reference
- Synthesis, biological evaluation, and in silico study of some unique multifunctional 1,2,4-triazole acetamidesSattar, Almas; Ur Rehman, Aziz; Abbasi, Muhammad Athar; Siddiqui, Sabahat Zahra; Rasool, Shahid; et al, Turkish Journal of Chemistry, 2018, 42(2), 401-417
Production Method 32
Reaction Conditions
1.1 Reagents: Hydrogen Catalysts: Ceria , Palladium (cerium dioxide-supported) ; 3.5 h, 2 MPa, 45 °C
Reference
- High Performance and Active Sites of a Ceria-Supported Palladium Catalyst for Solvent-Free Chemoselective Hydrogenation of NitroarenesShi, Xiuxiu; Wang, Xueguang; Shang, Xingfu; Zou, Xiujing; Ding, Weizhong; et al, ChemCatChem, 2017, 9(19), 3743-3751
Production Method 33
Reaction Conditions
1.1 Reagents: Trifluoromethanesulfonic acid , Azidotrimethylsilane Solvents: Methanol , Chloroform ; 2.7 min, 90 °C
1.2 Reagents: Methanol ; 90 °C
1.3 Reagents: Sodium bicarbonate Solvents: Water ; neutralized, rt
1.2 Reagents: Methanol ; 90 °C
1.3 Reagents: Sodium bicarbonate Solvents: Water ; neutralized, rt
Reference
- Continuous-Flow Electrophilic Amination of Arenes and Schmidt Reaction of Carboxylic Acids Utilizing the Superacidic Trimethylsilyl Azide/Triflic Acid Reagent SystemChen, Yuesu; Gutmann, Bernhard; Kappe, C. Oliver, Journal of Organic Chemistry, 2016, 81(19), 9372-9380
Production Method 34
Reaction Conditions
Reference
- Synthesis of 2-{(5-phenyl-l,3,4-Oxadiazol-2-yl)sulfanyl}_N-substituted acetamides as potential antimicrobial and hemolytic agentsAziz-ur-Rehman; Abbasi, Muhammad Athar; Siddiqui, Sabahat Zahra; Ahmad, Irshad; Shahid, Muhammad; et al, Pakistan Journal of Pharmaceutical Sciences, 2016, 29(3), 801-809
Production Method 35
Reaction Conditions
1.1 Reagents: Hydrogen Catalysts: Palladium (nanoclusters, nitrogen-doped mesoporous carbon-supported) ; 2 h, 1 MPa, rt → 45 °C
Reference
- Solvent-Free Selective Hydrogenation of Nitroarenes Using Nanoclusters of Palladium Supported on Nitrogen-Doped Ordered Mesoporous CarbonHuang, Haigen; Wang, Xueguang; Tan, Mingwu; Chen, Chenju; Zou, Xiujing; et al, ChemCatChem, 2016, 8(8), 1485-1489
Production Method 36
Reaction Conditions
1.1 Reagents: Pyridine , Tetrabutylammonium tetrafluoroborate Solvents: Acetonitrile ; 22 °C
1.2 Reagents: Piperidine ; 12 h, 80 °C
1.2 Reagents: Piperidine ; 12 h, 80 °C
Reference
- Electrochemical Amination of Less-Activated Alkylated Arenes Using Boron-Doped Diamond AnodesHerold, Sebastian; Moehle, Sabine; Zirbes, Michael; Richter, Frank; Nefzger, Hartmut; et al, European Journal of Organic Chemistry, 2016, 2016(7), 1274-1278
Production Method 37
Reaction Conditions
1.1 Reagents: Cuprous iodide , Hydrogen bromide Solvents: 1,2-Dichloroethane , Water ; 12 h, 120 °C
Reference
- Copper-Promoted Tandem Reaction of Azobenzenes with Allyl Bromides via N=N Bond Cleavage for the Regioselective Synthesis of QuinolinesYi, Xiangli; Xi, Chanjuan, Organic Letters, 2015, 17(23), 5836-5839
Production Method 38
Reaction Conditions
1.1 Reagents: Thiourea , Potassium tert-butoxide Solvents: Ethanol ; 12 h, 80 °C
Reference
- Catalyst-Free Chemoselective Reduction of Nitroarenes Using Thiourea as a Hydrogen SourceLv, Mei-fang; Lu, Guo-ping; Cai, Chun, Asian Journal of Organic Chemistry, 2015, 4(2), 141-144
Production Method 39
Reaction Conditions
1.1 Reagents: Oxygen , Poly(methylhydrosiloxane) Catalysts: Bis(acetylacetonato)nickel Solvents: 1,4-Dioxane ; 3 - 5 h, 80 °C
Reference
- Selective reduction of nitro-compounds to primary amines by nickel-catalyzed hydrosilylative reductionSun, Shuai; Quan, Zhengjun; Wang, Xicun, RSC Advances, 2015, 5(103), 84574-84577
Production Method 40
Reaction Conditions
1.1 Reagents: Ammonium formate Catalysts: 1604839-72-6 (silica-coated iron oxide-bound) Solvents: Water ; 20 h, 90 °C
Reference
- A Highly Water-Dispersible/Magnetically Separable Palladium Catalyst: Selective Transfer Hydrogenation or Direct Reductive N-Formylation of Nitroarenes in WaterKarimi, Babak; Mansouri, Fariborz; Vali, Hojatollah, ChemPlusChem, 2015, 80(12), 1750-1759
2,4-dimethylaniline Raw materials
- N-(2,4-dimethylphenyl)-2,2,2-trifluoroacetimidoyl chloride
- Diazene,1,2-bis(2,4-dimethylphenyl)-
- N-Hydroxy-4-nitrobenzimidamide
- 1,3-Bis(2,4-dimethylphenyl)urea
- Bis(2,4-dimethylphenyl)cadmium
- N-(2,4-Dimethylphenyl)acetamide
- 4-Chloro-m-xylene
- Amitraz
2,4-dimethylaniline Preparation Products
- 2,4-dimethylaniline (95-68-1)
- N′-(2,4-Dimethylphenyl)-N-formyl-N-methylmethanimidamide (2713973-21-6)
- 2,6-Dimethylaniline (87-62-7)
- 3,5-Dimethylaniline (108-69-0)
- 2-Bromo-4,6-dimethylaniline (41825-73-4)
- N-ethyl-2,4-dimethylaniline (1742-94-5)
- 1,2,4-Oxadiazole, 3-(4-nitrophenyl)-5-(trifluoromethyl)- (312633-84-4)
2,4-dimethylaniline Suppliers
Suzhou Senfeida Chemical Co., Ltd
Gold Member
(CAS:95-68-1)2,4-Dimethyl aniline
Order Number:1643834;sfd16380
Stock Status:in Stock
Quantity:Company Customization/200kg
Purity:98%/99.9%
Pricing Information Last Updated:Monday, 14 April 2025 21:49
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Tiancheng Chemical (Jiangsu) Co., Ltd
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(CAS:95-68-1)2,4-Dimethylaniline
Order Number:LE10707;LE1643834;LE5248
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:03
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Jiangsu Xinsu New Materials Co., Ltd
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(CAS:95-68-1)
Order Number:SFD2137
Stock Status:
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Wednesday, 11 December 2024 17:03
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2,4-dimethylaniline Related Literature
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Marcin Czapla,Jack Simons Phys. Chem. Chem. Phys., 2018,20, 21739-21745
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Ross Harder,David C. Dunand,Ian McNulty Nanoscale, 2017,9, 5686-5693
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Ziyang Deng,Changwei Chen,Sunliang Cui RSC Adv., 2016,6, 93753-93755
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Fereshteh Bayat Environ. Sci.: Nano, 2021,8, 367-389
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Denis V. Korchagin,Elena A. Yureva,Alexander V. Akimov,Eugenii Ya. Misochko,Gennady V. Shilov,Artem D. Talantsev,Roman B. Morgunov,Alexander A. Shakin,Sergey M. Aldoshin,Boris S. Tsukerblat Dalton Trans., 2017,46, 7540-7548
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Recommended suppliers
Suzhou Senfeida Chemical Co., Ltd
(CAS:95-68-1)2,4-Dimethyl aniline
Purity:98%/99.9%
Quantity:Company Customization/200kg
Price ($):Inquiry/Inquiry
Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:95-68-1)2,4-Dimethylaniline
Purity:99%/99%/99%
Quantity:25KG,200KG,1000KG/25KG,200KG,1000KG/25KG,200KG,1000KG
Price ($):Inquiry/Inquiry/Inquiry