Production Method 1

5392-12-1

947-62-6

Reaction Conditions

1.1 Reagents: Sodium carbonate ,  Permanganic acid (HMnO4), potassium salt (1:1) Solvents: Acetone ,  Water ;  rt; 8 h, rt
1.2 Reagents: Hydrogen peroxide Solvents: Water ;  rt
1.3 Reagents: Hydrochloric acid Solvents: Water ;  acidified

Reference

Preparation of piperazine derivatives for treatment mental and nervous system diseases

, China, , ,

Production Method 2

947-62-6

Reaction Conditions

Reference

Preparation of peptidyl pyrrolidine inhibitors of IAP proteins

, World Intellectual Property Organization, , ,

Production Method 3

947-62-6

Reaction Conditions

Reference

Benzo[a]pyrano[3,2-h]acridin-7-one derivatives, structurally related to acronycine, processes for their preparation, and pharmaceutical compositions for treatment of cancer

, European Patent Organization, , ,

Production Method 4

947-62-6

Reaction Conditions

Reference

Barriers to rotation about the chiral axis of tertiary aromatic amides

Ahmed, Anjum; Bragg, Ryan A.; Clayden, Jonathan; Lai, Lai Wah; McCarthy, Catherine; et al, Tetrahedron, 1998, 54(43), 13277-13294

Production Method 5

947-62-6

Reaction Conditions

Reference

Studies in stereochemistry. 47. Asymmetric induction by leaving group in nucleophilic aromatic substitution

Wilson, Janet M.; Cram, Donald J., Journal of Organic Chemistry, 1984, 49(25), 4930-43

Production Method 6

947-62-6

Reaction Conditions

Reference

Birch reduction of 2-methoxy-1-naphthoic acids

Oommen, P. Kurian, Australian Journal of Chemistry, 1975, 28(9), 2095-7

Production Method 7

141-82-2

93-04-9

947-62-6

5392-12-1

Reaction Conditions

1.1 Reagents: Manganese triacetate Solvents: Acetic acid

Reference

Manganese(III)-mediated formylation of aromatic compounds in the presence of malonic acid

Nishino, Hiroshi; Tsunoda, Katsunori; Kurosawa, Kazu, Bulletin of the Chemical Society of Japan, 1989, 62(2), 545-50

Production Method 8

93-04-9

947-62-6

883-62-5

Reaction Conditions

1.1 Reagents: Butyllithium Solvents: Diethyl ether

Reference

Heteroatom-facilitated lithiations

Gschwend, Heinz W.; Rodriguez, Herman R., Organic Reactions (Hoboken, 1979, 26,

Production Method 9

3401-47-6

947-62-6

883-62-5

Reaction Conditions

1.1 Solvents: Tetrahydrofuran ;  -78 °C
1.2 Reagents: sec-Butyllithium Solvents: Cyclohexane ;  1.25 h, -78 °C; 2 h, -78 °C → 30 °C
1.3 5 min, -30 °C

Reference

Synthesis of chiral binaphthyl derivatives

Wilson, Janet M., 1981, , ,

Production Method 10

13343-92-5

947-62-6

Reaction Conditions

1.1 Reagents: Sodium hydroxide Solvents: Methanol ,  Water ;  reflux
1.2 Reagents: Hydrochloric acid Solvents: Water ;  acidified

Reference

Preparation of 5-bromo-2-methoxy-6-alkyl benzoic acids as intermediates for agricultural fungicides

, United States, , ,

Production Method 11

13343-92-5

947-62-6

Reaction Conditions

1.1 Reagents: Sodium hydroxide Solvents: Methanol ,  Water ;  reflux

Reference

Preparation of fungicidal 2-methoxybenzophenones

, European Patent Organization, , ,

Production Method 12

2283-08-1

947-62-6

Reaction Conditions

1.1 Reagents: Potassium carbonate Solvents: Acetone ;  10 °C; 3 h, 50 °C
1.2 Reagents: Sodium hydroxide Solvents: Ethanol ,  Water ;  16 h, reflux
1.3 Reagents: Hydrochloric acid ;  pH 1

Reference

Practical Role of Racemization Rates in Deracemization Kinetics and Process Productivities

Oketani, Ryusei ; Hoquante, Marine; Brandel, Clement; Cardinael, Pascal; Coquerel, Gerard, Crystal Growth & Design, 2018, 18(11), 6417-6420

Production Method 13

3401-47-6

947-62-6

Reaction Conditions

1.1 Reagents: Magnesium ,  Dibromoethane Solvents: Diethyl ether ,  Benzene ;  1 h, reflux; 1 h, reflux; 2 h, reflux
1.2 10 min, reflux → rt

Reference

Synthesis of chiral binaphthyl derivatives

Wilson, Janet M., 1981, , ,

Production Method 14

13343-92-5

947-62-6

Reaction Conditions

1.1 Reagents: Sodium hydroxide Solvents: Methanol ,  Water ;  12 h, reflux; reflux → rt
1.2 Reagents: Hydrochloric acid Solvents: Water ;  pH 3, rt

Reference

Application of [4+2] cycloaddition reaction of tetrazine with cyclooctyne in the construction of pyridazine structure with axial chirality

Cai, Zhengjun; Gao, Jianbao; Li, Bai; Zhong, Yuan; Feng, Xing; et al, Youji Huaxue, 2018, 38(5), 1138-1146

Production Method 15

13101-92-3

947-62-6

Reaction Conditions

1.1 Reagents: 1,2-Bis(1-ethylpropyl)benzene ;  3 h, 3 - 6 °C; 1 h, rt
1.2 -

Reference

Aryllithiums with Increasing Steric Crowding and Lipophilicity Prepared from Chlorides in Diethyl Ether. The First Directly Prepared Room-Temperature-Stable Dilithioarenes

Screttas, Constantinos G.; Steele, Barry R.; Micha-Screttas, Maria; Heropoulos, Georgios A., Organic Letters, 2012, 14(22), 5680-5683

Production Method 16

13343-92-5

947-62-6

Reaction Conditions

1.1 Reagents: Sodium hydroxide Solvents: Water ;  12 h, reflux
1.2 Reagents: Hydrochloric acid Solvents: Water ;  neutralized, rt

Reference

Decarbonylative Halogenation by a Vanadium Complex

Rana, Sujoy; Haque, Rameezul; Santosh, Ganji; Maiti, Debabrata, Inorganic Chemistry, 2013, 52(6), 2927-2932

Production Method 17

2283-08-1

947-62-6

Reaction Conditions

Reference

Deracemization in a Complex Quaternary System with a Second-Order Asymmetric Transformation by Using Phase Diagram Studies

Oketani, Ryusei ; Marin, Francesco; Tinnemans, Paul ; Hoquante, Marine; Laurent, Anne; et al, Chemistry - A European Journal, 2019, 25(61), 13890-13898

Production Method 18

947-62-6

Reaction Conditions

Reference

Preparation of heterocyclyl- and naphthalenecarboxamide agrochemical fungicides

, Canada, , ,

Production Method 19

947-62-6

Reaction Conditions

Reference

Preparation of fungicides for control of take-all disease of plants.

, European Patent Organization, , ,

Production Method 20

947-62-6

Reaction Conditions

Reference

Regiospecific synthesis of polysubstituted naphthalenes via oxazoline-mediated nucleophilic aromatic substitutions and additions

Gant, Thomas G.; Meyers, A. I., Journal of the American Chemical Society, 1992, 114(3), 1010-15

Production Method 21

32721-21-4

947-62-6

93-04-9

Reaction Conditions

1.1 Reagents: Carbon dioxide ,  Triphenylphosphine ,  Tetraethylammonium p-toluenesulfonate Catalysts: Dichlorobis(triphenylphosphine)palladium Solvents: Dimethylformamide

Reference

Palladium(0)-catalyzed electroreductive carboxylation of aryl halides, β-bromostyrene, and allyl acetates with carbon dioxide

Torii, Sigeru; Tanaka, Hideo; Hamatani, Takeshi; Morisaki, Kazuo; Jutand, Anny; et al, Chemistry Letters, 1986, (2), 169-72

2-Methoxy-1-naphthoic acid Raw materials

• propanedioic acid
• 1-Iodo-2-methoxynaphthalene
• Methyl 2-methoxy-1-naphthoate
• 2-Hydroxy-1-naphthoic acid
• 1-Chloro-2-methoxynaphthalene
• 1-Bromo-2-methoxy-naphthalene
• 2-Methoxy-1-naphthaldehyde
• 2-Methoxynaphthalene

2-Methoxy-1-naphthoic acid Preparation Products

• 2-Methoxy-1-naphthoic acid (947-62-6)
• 3-methoxynaphthalene-2-carboxylic acid (883-62-5)
• 2-Methoxy-1-naphthaldehyde (5392-12-1)
• 2-Methoxynaphthalene (93-04-9)

• 1. An approach to 7-aza-1-phosphanorbornane complexes: strain promoted rearrangement of 1-iminylphosphirane complexes and cycloaddition with olefins?
  Yang Xu,Min Wang,Donghui Wei,Rongqiang Tian,Zheng Duan,Fran?ois Mathey Dalton Trans., 2019,48, 5523-5526
• 2. An anti-ultrasonic-stripping effect in confined micro/nanoscale cavities and its applications for efficient multiscale metallic patterning?
  Quan Xiang,Yiqin Chen,Zhiqin Li,Kaixi Bi,Guanhua Zhang,Huigao Duan Nanoscale, 2016,8, 19541-19550
• 3. An asymmetric supercapacitor based on controllable WO3 nanorod bundle and alfalfa-derived porous carbon?
  Kanjun Sun,Fengting Hua,Shuzhen Cui,Yanrong Zhu,Hui Peng,Guofu Ma RSC Adv., 2021,11, 37631-37642
• 4. An integrated cathode and solid electrolyte via in situ polymerization with significantly reduced interface resistance?
  Jialiang Yuan,Ran Dong,Yuan Li,Yang Liu,Zhuo Zheng,Yuxia Liu,Yan Sun,Benhe Zhong,Zhenguo Wu,Xiaodong Guo Chem. Commun., 2021,57, 13004-13007
• 5. An atom efficient route to N-aryl and N-alkyl pyrrolines by transition metal catalysis?
  Supaporn Sawadjoon,Joseph S. M. Samec Org. Biomol. Chem., 2011,9, 2548-2554

• Solvents and Organic Chemicals Organic Compounds Benzenoids Naphthalenes Naphthalenecarboxylic acids
• Solvents and Organic Chemicals Organic Compounds Benzenoids Naphthalenes Naphthalenecarboxylic acids and derivatives Naphthalenecarboxylic acids
• Solvents and Organic Chemicals Organic Compounds Acids/Esters

• 1951-38-8(2-Methoxyisophthalic acid)
• 883-62-5(3-methoxynaphthalene-2-carboxylic acid)
• 143355-56-0(3-Hydroxy-7-methoxy-2-naphthoic acid)
• 883-21-6(1-Methoxy-2-naphthoic Acid)
• 98410-68-5(3,5-Dimethoxy-2-naphthoic acid)
• 26507-91-5(2-Methoxy-3-methylbenzoic acid)
• 2224-00-2(2-Ethoxy-1-naphthoic acid)
• 62055-53-2(2-Naphthalenecarboxylic acid, 3,6-dimethoxy-)
• 728892-55-5(2-Naphthalenecarboxylic acid, 1,6-dimethoxy-)
• 79786-98-4(2-Naphthalenecarboxylicacid, 1-hydroxy-5-methoxy-)