- Small organic molecules as regulators of cell proliferation and their preparation, World Intellectual Property Organization, , ,
Cas no 946000-27-7 (4-Bromo-N,N-dimethylpyridin-2-amine)
946000-27-7 structure
Product Name:4-Bromo-N,N-dimethylpyridin-2-amine
CAS No:946000-27-7
MF:C7H9BrN2
MW:201.063760519028
MDL:MFCD11869615
CID:838794
PubChem ID:23436935
Update Time:2025-09-18
4-Bromo-N,N-dimethylpyridin-2-amine Chemical and Physical Properties
Names and Identifiers
-
- 4-Bromo-2-(dimethylamino)pyridine
- 4-Bromo-N,N-dimethylpyridin-2-amine
- (4-BROMO-PYRIDIN-2-YL)-DIMETHYL-AMINE
- HKZMXPYRQCDFCR-UHFFFAOYSA-N
- CM10673
- AB64930
- SY037279
- AB0027813
- W9695
- ST24023411
- 4-Bromo-N,N-dimethyl-2-pyridinamine (ACI)
- DTXSID10634097
- SCHEMBL786015
- AKOS015835334
- 4-Bromo-N pound notN-dimethylpyridin-2-amine
- (4-Bromo-pyridin-2-yl)-dimethyl-amine;4-Bromo-2-(dimethylamino)pyridine;
- 946000-27-7
- DS-14965
- CS-W006697
- MFCD11869615
- J-514832
-
- MDL： MFCD11869615
- Inchi： 1S/C7H9BrN2/c1-10(2)7-5-6(8)3-4-9-7/h3-5H,1-2H3
- InChI Key： HKZMXPYRQCDFCR-UHFFFAOYSA-N
- SMILES： BrC1C=C(N(C)C)N=CC=1
Computed Properties
- Exact Mass: 199.99491g/mol
- Monoisotopic Mass: 199.99491g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 2
- Heavy Atom Count: 10
- Rotatable Bond Count: 1
- Complexity: 106
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 16.1
- XLogP3: 2
Experimental Properties
- Density: 1.469±0.06 g/cm3 (20 oC 760 Torr),
- Boiling Point: 278.4±20.0 oC (760 Torr),
- Flash Point: 122.2±21.8 oC,
- Solubility: Slightly soluble (3 g/l) (25 o C),
4-Bromo-N,N-dimethylpyridin-2-amine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Fluorochem | 079119-250mg |
4-Bromo-2-(dimethylamino)pyridine |
946000-27-7 | 95% | 250mg |
￡53.00 | 2022-03-01 | |
| Fluorochem | 079119-1g |
4-Bromo-2-(dimethylamino)pyridine |
946000-27-7 | 95% | 1g |
￡115.00 | 2022-03-01 | |
| Fluorochem | 079119-5g |
4-Bromo-2-(dimethylamino)pyridine |
946000-27-7 | 95% | 5g |
￡463.00 | 2022-03-01 | |
| Fluorochem | 079119-25g |
4-Bromo-2-(dimethylamino)pyridine |
946000-27-7 | 95% | 25g |
￡1892.00 | 2022-03-01 | |
| TRC | B593623-50mg |
4-bromo-N,N-dimethylpyridin-2-amine |
946000-27-7 | 50mg |
$ 70.00 | 2022-06-07 | ||
| TRC | B593623-100mg |
4-bromo-N,N-dimethylpyridin-2-amine |
946000-27-7 | 100mg |
$ 95.00 | 2022-06-07 | ||
| TRC | B593623-500mg |
4-bromo-N,N-dimethylpyridin-2-amine |
946000-27-7 | 500mg |
$ 340.00 | 2022-06-07 | ||
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | B845440-250mg |
4-Bromo-N,N-dimethylpyridin-2-amine |
946000-27-7 | 98% | 250mg |
￥443.70 | 2022-09-02 | |
| Matrix Scientific | 075756-250mg |
4-Bromo-2-(dimethylamino)pyridine, 95+% |
946000-27-7 | 95+% | 250mg |
$352.00 | 2023-09-08 | |
| Matrix Scientific | 075756-1g |
4-Bromo-2-(dimethylamino)pyridine, 95+% |
946000-27-7 | 95+% | 1g |
$759.00 | 2023-09-08 |
4-Bromo-N,N-dimethylpyridin-2-amine Production Method
Production Method 1
Reaction Conditions
1.1 Reagents: Sodium hydride Solvents: Tetrahydrofuran ; 0 °C; 10 min, rt
1.2 16 h, rt
1.2 16 h, rt
Reference
Production Method 2
Reaction Conditions
1.1 Reagents: Sodium hydride Solvents: Tetrahydrofuran ; 0 °C; 0 °C → rt; 10 min, rt
1.2 16 h, rt
1.2 16 h, rt
Reference
- An improved method for the preparation of substituted N-(aminocyclohexyl)benzothiophene-2-carboxamides, World Intellectual Property Organization, , ,
Production Method 3
Reaction Conditions
1.1 Reagents: Sodium hydride Solvents: Tetrahydrofuran ; 30 min, 0 °C
1.2 0 °C → rt; 16 h, rt
1.2 0 °C → rt; 16 h, rt
Reference
- Preparation of heterocyclic compounds, especially substituted 1H-pyrazolo[3,4-d]pyrimidin-3-ones and analogs, as Wee1 inhibitors, United States, , ,
Production Method 4
Reaction Conditions
1.1 Reagents: Sodium tert-butoxide , Oxygen Solvents: Water ; 12 h, 140 °C; 140 °C → 25 °C
1.2 Reagents: Oxygen ; 25 °C
1.2 Reagents: Oxygen ; 25 °C
Reference
- Environmentally Benign, Base-Promoted Selective Amination of Polyhalogenated PyridinesSun, Chao; Yao, Wubing ; Chen, Xu; Zhao, Yiwen; Wei, Qiqi; et al, ACS Omega, 2019, 4(6), 10534-10538
Production Method 5
Reaction Conditions
1.1 Reagents: Sodium cyanoborohydride Solvents: Acetonitrile ; cooled
1.2 Reagents: Acetic acid ; rt
1.3 Reagents: Water ; 2 d, rt
1.4 Reagents: Sodium hydroxide Solvents: Water ; basified
1.2 Reagents: Acetic acid ; rt
1.3 Reagents: Water ; 2 d, rt
1.4 Reagents: Sodium hydroxide Solvents: Water ; basified
Reference
- Hydantoin compounds as MMP inhibitors useful in the treatment of diseases and their preparation, World Intellectual Property Organization, , ,
Production Method 6
Reaction Conditions
1.1 Reagents: Sodium iodide
Reference
- Preparation of piperazinylcarbonyl benzenesulfonamides for use in the treatment of cancer characterized as having an IDH mutation, World Intellectual Property Organization, , ,
Production Method 7
Reaction Conditions
1.1 Solvents: Tetrahydrofuran ; 2 h, 100 °C
Reference
- Preparation of imidazolopyrimidine derivatives as JAK inhibitors and therapeutic uses thereof, World Intellectual Property Organization, , ,
Production Method 8
Reaction Conditions
1.1 Reagents: Sodium hydride Solvents: Tetrahydrofuran ; 0 °C → rt; 5 min, rt
1.2 rt; 16 h, rt
1.3 Solvents: Water ; rt
1.2 rt; 16 h, rt
1.3 Solvents: Water ; rt
Reference
- Discovery and Characterization of Selective and Ligand-Efficient DYRK InhibitorsHenderson, Scott H. ; Sorrell, Fiona; Bennett, James; Fedorov, Oleg; Hanley, Marcus T.; et al, Journal of Medicinal Chemistry, 2021, 64(15), 11709-11728
Production Method 9
Reaction Conditions
Reference
- Preparation of phenylpyridine, bipyridine, pyrimidinylpyrazine and pyridylpyrazine compounds and methods of use thereof, World Intellectual Property Organization, , ,
Production Method 10
Reaction Conditions
Reference
- Small organic molecules as regulators of cell proliferation and their preparation, World Intellectual Property Organization, , ,
4-Bromo-N,N-dimethylpyridin-2-amine Raw materials
4-Bromo-N,N-dimethylpyridin-2-amine Preparation Products
4-Bromo-N,N-dimethylpyridin-2-amine Related Literature
-
Shintaro Takata,Yoshihiro Miura Phys. Chem. Chem. Phys., 2014,16, 24784-24789
-
Partha Laskar,Christine Dufès Nanoscale Adv., 2021,3, 6007-6026
-
Helga Garcia,Rui Ferreira,Marija Petkovic,Jamie L. Ferguson,Maria C. Leit?o,H. Q. Nimal Gunaratne,Luís Paulo N. Rebelo Green Chem., 2010,12, 367-369
-
Yukiya Kitayama Polym. Chem., 2014,5, 2784-2792
-
Norihito Fukui,Keisuke Fujimoto,Hideki Yorimitsu,Atsuhiro Osuka Dalton Trans., 2017,46, 13322-13341
946000-27-7 (4-Bromo-N,N-dimethylpyridin-2-amine) Related Products
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- 1142194-28-2(4-Bromo-N,N-diethylpyridin-2-amine)
- 84539-30-0(5-Bromo-2-(N-methylamino)pyridine)
- 468718-65-2(4-Bromo-N-methylpyridin-2-amine)
- 1352318-23-0(N-(4-Bromopyridin-2-yl)formamide)
- 1289089-99-1(N2-(4-bromo-2-pyridinyl)-N1,N1-dimethyl-1,2-Ethanediamine)
- 959992-71-3(7-Bromo-N-methylquinolin-2-amine)
- 79489-62-6(2-Quinolinamine, 6-bromo-N,N-dimethyl-)
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