Cas no 1142194-28-2 (4-Bromo-N,N-diethylpyridin-2-amine)

4-Bromo-N,N-diethylpyridin-2-amine is a brominated pyridine derivative featuring a diethylamino substituent at the 2-position. This compound serves as a versatile intermediate in organic synthesis, particularly in the preparation of pharmaceuticals, agrochemicals, and functional materials. The presence of both bromine and a diethylamino group enhances its reactivity, enabling selective cross-coupling reactions such as Suzuki-Miyaura or Buchwald-Hartwig amination. Its well-defined structure and high purity make it suitable for precise modifications in drug discovery and material science applications. The compound’s stability under standard conditions ensures reliable handling and storage, while its synthetic utility supports the development of complex molecular architectures.
4-Bromo-N,N-diethylpyridin-2-amine structure
1142194-28-2 structure
Product Name:4-Bromo-N,N-diethylpyridin-2-amine
CAS No:1142194-28-2
MF:C9H13BrN2
MW:229.116921186447
MDL:MFCD11869617
CID:1025011
PubChem ID:45787900
Update Time:2025-08-02

4-Bromo-N,N-diethylpyridin-2-amine Chemical and Physical Properties

Names and Identifiers

    • 4-Bromo-N,N-diethylpyridin-2-amine
    • BS-19256
    • 1142194-28-2
    • CS-0441315
    • A894238
    • AKOS015895006
    • MFCD11869617
    • SCHEMBL22306680
    • DTXSID70671706
    • 2-Pyridinamine, 4-bromo-N,N-diethyl-
    • MDL: MFCD11869617
    • Inchi: 1S/C9H13BrN2/c1-3-12(4-2)9-7-8(10)5-6-11-9/h5-7H,3-4H2,1-2H3
    • InChI Key: RPWJQOUHBJCQCA-UHFFFAOYSA-N
    • SMILES: BrC1C=CN=C(C=1)N(CC)CC

Computed Properties

  • Exact Mass: 228.02600
  • Monoisotopic Mass: 228.02621g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 3
  • Complexity: 126
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 3.3
  • Topological Polar Surface Area: 16.1?2

Experimental Properties

  • PSA: 16.13000
  • LogP: 2.69030

4-Bromo-N,N-diethylpyridin-2-amine Security Information

4-Bromo-N,N-diethylpyridin-2-amine Customs Data

  • HS CODE:2933399090
  • Customs Data:

    China Customs Code:

    2933399090

    Overview:

    2933399090. Other compounds with non fused pyridine rings in structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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Additional information on 4-Bromo-N,N-diethylpyridin-2-amine

Introduction to 4-Bromo-N,N-diethylpyridin-2-amine (CAS No. 1142194-28-2)

The compound 4-Bromo-N,N-diethylpyridin-2-amine, with the CAS registry number 1142194-28-2, is a fascinating molecule that has garnered significant attention in the fields of organic chemistry and pharmacology. This compound belongs to the class of pyridine derivatives, which are known for their versatile applications in drug design and materials science. The structure of 4-Bromo-N,N-diethylpyridin-2-amine consists of a pyridine ring substituted with a bromine atom at the 4-position and an N,N-diethylamino group at the 2-position. This unique substitution pattern imparts distinctive electronic and steric properties to the molecule, making it a valuable building block in synthetic chemistry.

Recent studies have highlighted the potential of pyridine derivatives like 4-Bromo-N,N-diethylpyridin-2-amine in various therapeutic areas. For instance, researchers have explored its role as a precursor in the synthesis of bioactive compounds targeting neurodegenerative diseases. The bromine substituent at the 4-position facilitates nucleophilic aromatic substitution reactions, enabling the incorporation of diverse functional groups. This feature has been exploited in the development of novel agents with potential anti-inflammatory and antioxidant activities.

In addition to its pharmaceutical applications, 4-Bromo-N,N-diethylpyridin-2-amine has found utility in materials science. Its ability to act as a ligand in coordination chemistry has led to its use in the synthesis of metal complexes with interesting magnetic and catalytic properties. Recent advancements in this area have demonstrated its potential as a precursor for creating nanomaterials with applications in sensing and energy storage.

The synthesis of 4-Bromo-N,N-diethylpyridin-2-amine typically involves multi-step processes, including nucleophilic aromatic substitution and amine alkylation. These methods have been optimized to achieve high yields and purity, ensuring its availability for research and industrial applications. The compound's stability under various reaction conditions further enhances its appeal as a versatile intermediate in organic synthesis.

From an environmental standpoint, understanding the degradation pathways of 4-Bromo-N,N-diethylpyridin-2-amine is crucial for assessing its ecological impact. Recent studies have investigated its biodegradation under aerobic and anaerobic conditions, providing insights into its persistence in different ecosystems. These findings are essential for guiding safe handling practices and regulatory compliance.

In conclusion, 4-Bromo-N,N-diethylpyridin-2-amine (CAS No. 1142194-28-2) stands out as a multifaceted compound with promising applications across diverse scientific domains. Its unique chemical properties, coupled with ongoing research into its biological and material applications, position it as a key player in future innovations within organic chemistry and beyond.

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