Production Method 1

1826-67-1

91678-23-8

945840-69-7

Reaction Conditions

1.1 Solvents: Tetrahydrofuran ;  -78 °C; 1 h, -50 °C
1.2 Solvents: Water ;  -50 °C

Reference

A Unique Approach to Design Potent and Selective Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP) Inhibitors

Bronner, Sarah M. ; Murray, Jeremy; Romero, F. Anthony ; Lai, Kwong Wah; Tsui, Vickie; et al, Journal of Medicinal Chemistry, 2017, 60(24), 10151-10171

Production Method 2

1826-67-1

91678-23-8

945840-69-7

Reaction Conditions

1.1 Solvents: Tetrahydrofuran ;  -78 °C; 1 h, -50 °C
1.2 Reagents: Ammonium chloride Solvents: Water

Reference

Alkynyl alcohols as NIK kinase inhibitors and their preparation

, World Intellectual Property Organization, , ,

Production Method 3

1826-67-1

91678-23-8

945840-69-7

Reaction Conditions

1.1 Solvents: Tetrahydrofuran ;  -78 °C; 18 h, -78 °C → rt
1.2 Reagents: Ammonium chloride Solvents: Water ;  rt

Reference

Heterobicyclic amide compounds as CETP protein inhibitors, their preparation, pharmaceutical compositions, and use in therapy

, United States, , ,

7-Bromo-5-chloro-1H-pyrrolo[2,3-c]pyridine Raw materials

• vinylmagnesium bromide solution
• 2-bromo-6-chloro-3-nitro-pyridine

7-Bromo-5-chloro-1H-pyrrolo[2,3-c]pyridine Preparation Products

• 7-Bromo-5-chloro-1H-pyrrolo[2,3-c]pyridine (945840-69-7)

• 1. Esterase-responsive polymeric prodrug-based tumor targeting nanoparticles for improved anti-tumor performance against colon cancer?
  Gang Pan,Yi-jie Bao,Jie Xu,Tao Liu,Cheng Liu,Yan-yan Qiu,Xiao-jing Shi,Hui Yu,Ting-ting Jia,Xia Yuan,Ze-ting Yuan,Yi-jun Cao RSC Adv., 2016,6, 42109-42119
• 2. Emergence of cationic polyamine dendrimersomes: design, stimuli sensitivity and potential biomedical applications
  Partha Laskar,Christine Dufès Nanoscale Adv., 2021,3, 6007-6026
• 3. Evolution in surface coverage of CH3NH3PbI3?XClXvia heat assisted solvent vapour treatment and their effects on photovoltaic performance of devices
  Dhirendra K. Chaudhary,Pramendra Kumar,Lokendra Kumar RSC Adv., 2016,6, 94731-94738
• 4. Enabling shape memory and healable effects in a conjugated polymer by incorporating siloxane via dynamic imine bond?
  Yaling Zhang,Chunhui Dai,Shiwei Zhou,Bin Liu Chem. Commun., 2018,54, 10092-10095
• 5. Dissociation of large gaseous serine clusters produces abundant protonated serine octamer
  Jacob S. Jordan,Evan R. Williams Analyst, 2021,146, 2617-2625

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyrrolopyridines Pyrrolopyridines
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyrrolopyridines

• 1246554-46-0(6-bromo-2-chloro-1,7-naphthyridine)
• 1190309-88-6(7-Bromo-3-chloro-1H-pyrrolo[2,3-c]pyridine)
• 1260666-72-5(2-Bromo-8-chloro-1,7-naphthyridine)
• 1246549-09-6(2-Bromo-6-chloro-1,7-naphthyridine)
• 1799727-36-8(2-bromo-5-chloro-1H-pyrrolo[3,2-b]pyridine)
• 2231674-73-8(2-bromo-5-chloro-1H-pyrrolo[2,3-c]pyridine)
• 39068-98-9(2-Chloro-9-bromo-1,10-phenanthroline)
• 446284-44-2(7-bromo-4-chloro-1h-pyrrolo[2,3-c]pyridine)
• 1198096-48-8(5-Bromo-7-chloro-1h-pyrrolo2,3-cpyridine)
• 1782490-76-9(2-bromo-7-chloro-1H-pyrrolo[2,3-c]pyridine)