- Preparation of triazolopyridazine protein kinase modulators, World Intellectual Property Organization, , ,
Cas no 944937-53-5 (6-Bromo-1H-pyrrolo[3,2-b]pyridine)
944937-53-5 structure
Product Name:6-Bromo-1H-pyrrolo[3,2-b]pyridine
CAS No:944937-53-5
MF:C7H5BrN2
MW:197.032000303268
MDL:MFCD09266227
CID:796719
PubChem ID:24229256
Update Time:2024-10-25
6-Bromo-1H-pyrrolo[3,2-b]pyridine Chemical and Physical Properties
Names and Identifiers
-
- 6-Bromo-1H-pyrrolo[3,2-b]pyridine
- 1H-Pyrrolo[3,2-b]pyridine,6-bromo-
- 6-Bromo-4-azaindole
- 6-Bromo-1H-pyrrolo[3,2-b]pyridine (ACI)
- Z1198219527
- 6-bromanyl-1H-pyrrolo[3,2-b]pyridine
- EN300-192189
- MFCD09266227
- FT-0653827
- 944937-53-5
- CS-W008287
- 6-Bromo-1H-pyrrolo[3,2-b]pyridine, AldrichCPR
- AKOS006331621
- OJFFFCVPCVATIV-UHFFFAOYSA-N
- FS-3080
- A844985
- SCHEMBL10535
- AC-9429
- SY018872
- DTXSID80640145
- AM20061639
- BBL102049
- STL555848
-
- MDL: MFCD09266227
- Inchi: 1S/C7H5BrN2/c8-5-3-7-6(10-4-5)1-2-9-7/h1-4,9H
- InChI Key: OJFFFCVPCVATIV-UHFFFAOYSA-N
- SMILES: BrC1C=NC2C=CNC=2C=1
Computed Properties
- Exact Mass: 195.96400
- Monoisotopic Mass: 195.964
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 1
- Heavy Atom Count: 10
- Rotatable Bond Count: 0
- Complexity: 129
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 1.8
- Topological Polar Surface Area: 28.7A^2
Experimental Properties
- Density: 1.770
- Boiling Point: 311 oC
- Flash Point: 142 oC
- Refractive Index: 1.727
- PSA: 28.68000
- LogP: 2.32540
6-Bromo-1H-pyrrolo[3,2-b]pyridine Security Information
-
Symbol:
- Signal Word:Danger
- Hazard Statement: H302-H315-H318-H335
- Warning Statement: P261-P280-P305+P351+P338
- Hazardous Material transportation number:NONH for all modes of transport
- WGK Germany:3
- Hazard Category Code: 22-36/37/38
- Safety Instruction: 26
-
Hazardous Material Identification:
- HazardClass:IRRITANT
6-Bromo-1H-pyrrolo[3,2-b]pyridine Customs Data
- HS CODE:2933990090
- Customs Data:
China Customs Code:
2933990090Overview:
2933990090. Other heterocyclic compounds containing only nitrogen heteroatoms. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%
Declaration elements:
Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date
Summary:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
6-Bromo-1H-pyrrolo[3,2-b]pyridine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| JIE DA WEI ( SHANG HAI ) YI YAO KE JI FA ZHAN Co., Ltd. | 48R0612-5g |
6-Bromo-1H-pyrrolo[3,2-b]pyridine |
944937-53-5 | 96% | 5g |
636.03CNY | 2021-05-08 | |
| JIE DA WEI ( SHANG HAI ) YI YAO KE JI FA ZHAN Co., Ltd. | 48R0612-25g |
6-Bromo-1H-pyrrolo[3,2-b]pyridine |
944937-53-5 | 96% | 25g |
2120.11CNY | 2021-05-08 | |
| JIE DA WEI ( SHANG HAI ) YI YAO KE JI FA ZHAN Co., Ltd. | 48R0612-100g |
6-Bromo-1H-pyrrolo[3,2-b]pyridine |
944937-53-5 | 96% | 100g |
7123.56CNY | 2021-05-08 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | 026243-300mg |
6-Bromo-1H-pyrrolo[3,2-b]pyridine |
944937-53-5 | 300mg |
324.0CNY | 2021-08-04 | ||
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-YH073-250mg |
6-Bromo-1H-pyrrolo[3,2-b]pyridine |
944937-53-5 | 97% | 250mg |
90CNY | 2021-05-08 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-YH073-5g |
6-Bromo-1H-pyrrolo[3,2-b]pyridine |
944937-53-5 | 97% | 5g |
489.0CNY | 2021-08-04 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-YH073-1g |
6-Bromo-1H-pyrrolo[3,2-b]pyridine |
944937-53-5 | 97% | 1g |
136.0CNY | 2021-08-04 | |
| Matrix Scientific | 026243-25g |
6-Bromo-1H-pyrrolo[3,2-b]pyridine |
944937-53-5 | 25g |
$415.00 | 2023-09-09 | ||
| XI GE MA AO DE LI QI ( SHANG HAI ) MAO YI Co., Ltd. | ADE000947-1G |
6-Bromo-1H-pyrrolo[3,2-b]pyridine |
944937-53-5 | Aldrich | 1G |
¥8753.36 | 2022-02-24 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-YH073-20g |
6-Bromo-1H-pyrrolo[3,2-b]pyridine |
944937-53-5 | 97% | 20g |
1761.0CNY | 2021-08-04 |
6-Bromo-1H-pyrrolo[3,2-b]pyridine Production Method
Production Method 1
Reaction Conditions
1.1 Solvents: Dimethylformamide ; 1 h, 100 °C; 100 °C → rt
1.2 Reagents: Acetic acid , Iron Solvents: Acetic acid ; 21 h, 100 °C; 100 °C → rt
1.3 Reagents: Methanol ; rt
1.2 Reagents: Acetic acid , Iron Solvents: Acetic acid ; 21 h, 100 °C; 100 °C → rt
1.3 Reagents: Methanol ; rt
Reference
Production Method 2
Reaction Conditions
1.1 Reagents: Iron Solvents: Acetic acid ; overnight, 100 °C
Reference
- Preparation of substituted benzofuran compounds and methods of use thereof for the treatment of viral diseases, World Intellectual Property Organization, , ,
Production Method 3
Reaction Conditions
1.1 Reagents: Hydrazine hydrate (1:1) Catalysts: Iron chloride (FeCl3) Solvents: Isopropanol , Water ; 2 h, 30 - 70 °C; 20 h, 80 ± 5 °C
Reference
- Azaindole derivatives which act as PI3K inhibitors and their preparation, World Intellectual Property Organization, , ,
Production Method 4
Reaction Conditions
1.1 Reagents: Acetic acid , Iron ; 10 min, 0 °C
1.2 Reagents: Acetic acid ; 3 h, rt
1.2 Reagents: Acetic acid ; 3 h, rt
Reference
- A Scaffold-Hopping Strategy toward the Identification of Inhibitors of Cyclin G Associated KinaseWouters, Randy; Tian, Junjun; Herdewijn, Piet; De Jonghe, Steven, ChemMedChem, 2019, 14(2), 237-254
Production Method 5
Reaction Conditions
1.1 Solvents: Dimethylformamide ; 1 h, rt → 100 °C
1.2 Reagents: Iron Solvents: Acetic acid ; 20 h, rt → 100 °C
1.2 Reagents: Iron Solvents: Acetic acid ; 20 h, rt → 100 °C
Reference
- Preparation of imidazolopyridines and -pyrimidines as tricyclic DLK inhibitors and uses thereof, World Intellectual Property Organization, , ,
Production Method 6
Reaction Conditions
1.1 Reagents: Iron Solvents: Acetic acid ; overnight, 100 °C
Reference
- Substituted benzofuran compounds and methods of use thereof for the treatment of viral diseases, World Intellectual Property Organization, , ,
Production Method 7
Reaction Conditions
1.1 Reagents: Iron Solvents: Acetic acid ; 5 h, rt → 80 °C
Reference
- Compound functioning as bromodomain protein inhibitor, and composition, World Intellectual Property Organization, , ,
Production Method 8
Reaction Conditions
Reference
- GluN2B subunit-targeted positron tracer for central nervous system and preparation thereof, China, , ,
6-Bromo-1H-pyrrolo[3,2-b]pyridine Raw materials
- (dimethoxymethyl)dimethylamine
- 5-bromo-2-methyl-3-nitro-pyridine
- (E)-5-Bromo-3-nitropyridinyl-2-N,N-dimethylethenamine
- (Z)-2-(5-bromo-3-nitropyridin-2-yl)ethenyldimethylamine
6-Bromo-1H-pyrrolo[3,2-b]pyridine Preparation Products
6-Bromo-1H-pyrrolo[3,2-b]pyridine Related Literature
-
Shintaro Takata,Yoshihiro Miura Phys. Chem. Chem. Phys., 2014,16, 24784-24789
-
Joseph W. Bennett,Diamond T. Jones,Blake G. Hudson,Joshua Melendez-Rivera,Robert J. Hamers,Sara E. Mason Environ. Sci.: Nano, 2020,7, 1642-1651
-
Albertus D. Handoko,Khoong Hong Khoo,Teck Leong Tan,Hongmei Jin,Zhi Wei Seh J. Mater. Chem. A, 2018,6, 21885-21890
-
Hongxia Li,Aikifa Raza,Qiaoyu Ge,Jin-You Lu,TieJun Zhang Soft Matter, 2020,16, 6841-6849
-
Yi Cao,Yujiao Xiahou,Lixiang Xing,Xiang Zhang,Hong Li,ChenShou Wu,Haibing Xia Nanoscale, 2020,12, 20456-20466
944937-53-5 (6-Bromo-1H-pyrrolo[3,2-b]pyridine) Related Products
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- 23688-47-3(3-Bromo-1H-pyrrolo[3,2-b]pyridine)
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- 929074-45-3(8-Bromopyrido[3,4-b]pyrazine)
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