Production Method 1

253801-04-6

944899-01-8

Reaction Conditions

1.1 Reagents: Sodium hydroxide ,  Iodine Solvents: Dimethylformamide ;  overnight, rt

Reference

Process for preparation of substituted phenylpropenylpyridine derivative and medical use thereof

, World Intellectual Property Organization, , ,

Production Method 2

253801-04-6

944899-01-8

Reaction Conditions

1.1 Reagents: Sodium hydroxide ,  Iodine Solvents: 1,4-Dioxane ,  Water ;  2 h, rt

Reference

Preparation of dihydropyridine derivatives as protein kinase inhibitors

, World Intellectual Property Organization, , ,

Production Method 3

253801-04-6

944899-01-8

Reaction Conditions

1.1 Reagents: Potassium hydroxide ,  Iodine Solvents: Dimethylformamide ;  4 h, rt
1.2 Reagents: Sodium thiosulfate Solvents: Water

Reference

Substituted aminothiazolone indazoles as estrogen related receptor-α modulators and their preparation and use in the treatment of diseases

, World Intellectual Property Organization, , ,

Production Method 4

253801-04-6

944899-01-8

Reaction Conditions

1.1 Reagents: Sodium hydroxide ,  Iodine Solvents: 1,4-Dioxane ,  Water ;  2 h, rt

Reference

Indazolyl-substituted dihydroisoxazolopyridines as c-Met tyrosine kinase inhibitors and their preparation

, World Intellectual Property Organization, , ,

Production Method 5

944899-01-8

Reaction Conditions

Reference

Indazolyl-substituted dihydroisoxa-zolopyridines and methods of use thereof

, United States, , ,

Production Method 6

253801-04-6

944899-01-8

Reaction Conditions

1.1 Reagents: Sodium hydroxide ,  Iodine Solvents: 1,4-Dioxane ,  Water ;  2 h, rt

Reference

4-Indazolyl-1,4-dihydropyridine derivatives as c-Met protein tyrosine kinase inhibitors and their preparation, pharmaceutical compositions and use in the treatment of cancers

, World Intellectual Property Organization, , ,

Production Method 7

253801-04-6

944899-01-8

Reaction Conditions

1.1 Reagents: Potassium carbonate ,  Iodine Solvents: Dimethylformamide ;  rt; 3 h, rt
1.2 Reagents: Potassium carbonate ,  Sodium dithionite Solvents: Water ;  2 h, rt
1.3 Reagents: Sodium bisulfate Solvents: Water ;  rt

Reference

Preparation of indazolyl, benzimidazolyl, benzotriazolyl substituted indolin-2-one derivatives as kinase inhibitors useful in the treatment of cancer

, World Intellectual Property Organization, , ,

Production Method 8

253801-04-6

944899-01-8

Reaction Conditions

1.1 Reagents: Potassium carbonate ,  Iodine Solvents: Dimethylformamide ;  rt; 3 h, rt
1.2 Reagents: Potassium carbonate ,  Sodium dithionite Solvents: Water ;  2 h, rt

Reference

Preparation of 3-indazolylbenzenesulfonamides as kinase inhibitors useful in treating cancer

, World Intellectual Property Organization, , ,

Production Method 9

253801-04-6

944899-01-8

Reaction Conditions

1.1 Reagents: Potassium hydroxide ,  Iodine Solvents: Dimethylformamide ;  30 min, cooled; 6 h, rt
1.2 Reagents: Sodium thiosulfate Solvents: Water ;  rt

Reference

Substituted thiazolidinedione indazoles, indoles and benzotriazoles as estrogen related receptor-α modulators and their preparation and use in the treatment of diseases

, World Intellectual Property Organization, , ,

Production Method 10

944899-01-8

Reaction Conditions

Reference

Substituted 4-(indazolyl)-1,4-dihydropyridines and methods of use thereof

, United States, , ,

3-Iodo-1H-indazole-5-carbaldehyde Raw materials

• 1H-Indazole-5-carbaldehyde

3-Iodo-1H-indazole-5-carbaldehyde Preparation Products

• 3-Iodo-1H-indazole-5-carbaldehyde (944899-01-8)

• 1. Emulsion soft templating of carbide-derived carbon nanospheres with controllable porosity for capacitive electrochemical energy storage?
  M. Zeiger,N. J?ckel,P. Strubel,L. Borchardt,R. Reinhold,W. Nickel,J. Eckert,V. Presser,S. Kaskel J. Mater. Chem. A, 2015,3, 17983-17990
• 2. Evolution in surface coverage of CH3NH3PbI3?XClXvia heat assisted solvent vapour treatment and their effects on photovoltaic performance of devices
  Dhirendra K. Chaudhary,Pramendra Kumar,Lokendra Kumar RSC Adv., 2016,6, 94731-94738
• 3. Fast synthesis of red Li3BaSrLn3(WO4)8:Eu3+ phosphors for white LEDs under near-UV excitation by a microwave-assisted solid state reaction method and photoluminescence studies
  Bo Wei,Zhenyu Liu,Chen Xie,Shu Yang,Wentao Tang,Aiwei Gu,Wing-Tak Wong,Ka-Leung Wong J. Mater. Chem. C, 2015,3, 12322-12327
• 4. Fe/S-Catalyzed synthesis of 2-benzoylbenzoxazoles and 2-quinolylbenzoxazoles via redox condensation of o-nitrophenols with acetophenones and methylquinolines?
  Thi Thu Tram Nguyen,Thanh Binh Nguyen Org. Biomol. Chem., 2021,19, 6015-6020
• 5. Emerging investigator series: first-principles and thermodynamics comparison of compositionally-tuned delafossites: cation release from the (001) surface of complex metal oxides?
  Joseph W. Bennett,Diamond T. Jones,Blake G. Hudson,Joshua Melendez-Rivera,Robert J. Hamers,Sara E. Mason Environ. Sci.: Nano, 2020,7, 1642-1651

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Benzopyrazoles Indazoles

• 1227269-40-0(3-Iodo-6-phenyl-(1H)indazole)
• 847906-27-8(3-iodo-7-methyl-2H-indazole)
• 1086391-11-8(3-Iodo-1H-indazole-6-carboxylic acid)
• 885518-96-7(3-Iodo-6-methyl-1H-indazole)
• 847906-31-4(3-Iodo-5,7-dimethyl (1H)indazole)
• 885522-63-4(3-Iodo-4-methyl-1H-indazole)
• 885518-92-3(3-Iodo-5-methyl-1H-indazole)
• 885520-80-9(3-Iodo-1H-indazole-4-carboxylic acid)
• 885521-46-0(3-Iodo-1H-indazole-5-carboxylic acid)
• 885271-25-0(Methyl 3-iodo-1H-indazole-5-carboxylate)