Production Method 1

1789733-04-5

933745-52-9

Reaction Conditions

1.1 Reagents: Trifluoroacetic acid Solvents: Acetone ,  Water ;  overnight, 40 °C
1.2 Reagents: Sodium bicarbonate Solvents: Water ;  neutralized

Reference

Steric interference on the redox-conjugated pyrimidine ring rotation of mono- and dinuclear copper complexes with (4-methyl-2-pyrimidinyl)imine ligands

Hattori, Yohei; Nishikawa, Michihiro; Kusamoto, Tetsuro; Kume, Shoko; Nishihara, Hiroshi, Chemistry Letters, 2014, 43(7), 1037-1039

Production Method 2

142650-13-3

933745-52-9

Reaction Conditions

1.1 Reagents: Dimethyl sulfoxide ,  Oxalyl chloride Solvents: Dichloromethane ;  rt → -78 °C; 2 h, -78 °C
1.2 Reagents: Triethylamine ;  overnight, -78 °C → rt
1.3 Reagents: Water ;  1 h, rt

Reference

Pyrido[2,3-d]pyrimidin-4-one derivatives as tankyrase inhibitors and their preparation and use for the treatment of cancer

, World Intellectual Property Organization, , ,

Production Method 3

933745-52-9

Reaction Conditions

Reference

Heteroaryl compounds as inhibitors of plasma kallikrein and their preparation

, World Intellectual Property Organization, , ,

4-methylpyrimidine-2-carbaldehyde Raw materials

• Pyrimidine, 2-(diethoxymethyl)-4-methyl-
• (4-Methylpyrimidin-2-yl)methanol

4-methylpyrimidine-2-carbaldehyde Preparation Products

• 4-methylpyrimidine-2-carbaldehyde (933745-52-9)

• 1. Evolution of dealloying induced strain in nanoporous gold crystals?
  Ross Harder,David C. Dunand,Ian McNulty Nanoscale, 2017,9, 5686-5693
• 2. Distinct correlation between (CN2)x units and pores: a low-cost method for predesigned wide range control of micropore size of porous carbon?
  Xiaotong Feng,Lei Bian,Jie Ma,Lei Zhou,Xiayan Wang,Guangsheng Guo,Qiaosheng Pu Chem. Commun., 2019,55, 3963-3966
• 3. Elusive 2-aminofuran Diels–Alder substrates for a straightforward synthesis of polysubstituted anilines?
  Ana G. Neo,Ana Bornadiego,Jesús Díaz,Stefano Marcaccini,Carlos F. Marcos Org. Biomol. Chem., 2013,11, 6546-6555
• 4. Evolution in surface coverage of CH3NH3PbI3?XClXvia heat assisted solvent vapour treatment and their effects on photovoltaic performance of devices
  Dhirendra K. Chaudhary,Pramendra Kumar,Lokendra Kumar RSC Adv., 2016,6, 94731-94738
• 5. Fe3O4 nanoclusters highly dispersed on a porous graphene support as an additive for improving the hydrogen storage properties of LiBH4?
  Guang Xu,Wei Zhang,Ying Zhang,Xiaoxia Zhao,Ping Wen,Di Ma RSC Adv., 2018,8, 19353-19361

• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Carbonyl compounds Aldehydes

• 1004-17-7(2-Methylpyrimidine-4-carbaldehyde)
• 22114-27-8(2,4,6-trimethylpyrimidine)
• 64571-50-2(Ethanone,1-(4,6-dimethyl-2-pyrimidinyl)-)
• 1074-39-1(2,6-Dimethylpyrimidine-4-carbaldehyde)
• 933738-87-5(4-Methylpyrimidine-2-carboxylic acid)
• 2435-50-9(Pyrimidine-4-carbaldehyde)
• 71850-85-6(1-(4-methylpyrimidin-2-yl)ethan-1-one)
• 14331-54-5(2,4-Dimethylpyrimidine)
• 27427-90-3(4,6-Dimethylpyrimidine-2-carbaldehyde)
• 126534-98-3(2-formylpyrimidine-4-carbonitrile)