- Preparation of piperazine pentanamide HIV protease inhibitors and methods of treating AIDS, World Intellectual Property Organization, , ,
Cas no 933724-95-9 (3-(1,3-thiazol-5-yl)propanoic acid)
933724-95-9 structure
Product Name:3-(1,3-thiazol-5-yl)propanoic acid
CAS No:933724-95-9
MF:C6H7NO2S
MW:157.190280199051
MDL:MFCD17267444
CID:999658
PubChem ID:45121677
Update Time:2024-10-26
3-(1,3-thiazol-5-yl)propanoic acid Chemical and Physical Properties
Names and Identifiers
-
- 5-Thiazolepropanoic acid
- 3-(1,3-thiazol-5-yl)propanoic acid
- 3-(Thiazol-5-yl)propanoicacid
- EN300-223524
- CS-0159433
- BS-51054
- DS-017002
- SCHEMBL2517712
- DTXSID50669222
- 3-(Thiazol-5-yl)propanoic acid
- 933724-95-9
- 5-THIAZOLEPROPANOIC ACID
-
- MDL： MFCD17267444
- Inchi： 1S/C6H7NO2S/c8-6(9)2-1-5-3-7-4-10-5/h3-4H,1-2H2,(H,8,9)
- InChI Key： GHLKHRAWUVKIQA-UHFFFAOYSA-N
- SMILES： O=C(CCC1=CN=CS1)O
Computed Properties
- Exact Mass: 157.02
- Monoisotopic Mass: 157.02
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 10
- Rotatable Bond Count: 3
- Complexity: 129
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 78.4A^2
- XLogP3: 0.7
3-(1,3-thiazol-5-yl)propanoic acid Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-LK560-50mg |
3-(1,3-thiazol-5-yl)propanoic acid |
933724-95-9 | 97% | 50mg |
412.0CNY | 2021-07-09 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-LK560-200mg |
3-(1,3-thiazol-5-yl)propanoic acid |
933724-95-9 | 97% | 200mg |
1032.0CNY | 2021-07-09 | |
| SHANG HAI BI DE YI YAO KE JI GU FEN Co., Ltd. | BD552556-100mg |
3-(Thiazol-5-yl)propanoic acid |
933724-95-9 | 97% | 100mg |
￥457.0 | 2024-04-17 | |
| SHANG HAI BI DE YI YAO KE JI GU FEN Co., Ltd. | BD552556-250mg |
3-(Thiazol-5-yl)propanoic acid |
933724-95-9 | 97% | 250mg |
￥685.0 | 2024-04-17 | |
| SHANG HAI BI DE YI YAO KE JI GU FEN Co., Ltd. | BD552556-1g |
3-(Thiazol-5-yl)propanoic acid |
933724-95-9 | 97% | 1g |
￥1905.0 | 2024-04-17 | |
| Chemenu | CM392084-100mg |
3-(1,3-thiazol-5-yl)propanoic acid |
933724-95-9 | 95%+ | 100mg |
$107 | 2024-07-19 | |
| Chemenu | CM392084-250mg |
3-(1,3-thiazol-5-yl)propanoic acid |
933724-95-9 | 95%+ | 250mg |
$161 | 2024-07-19 | |
| Chemenu | CM392084-500mg |
3-(1,3-thiazol-5-yl)propanoic acid |
933724-95-9 | 95%+ | 500mg |
$670 | 2022-12-31 | |
| Chemenu | CM392084-1g |
3-(1,3-thiazol-5-yl)propanoic acid |
933724-95-9 | 95%+ | 1g |
$419 | 2024-07-19 | |
| Alichem | A059006832-250mg |
3-(Thiazol-5-yl)propanoic acid |
933724-95-9 | 95% | 250mg |
$417.30 | 2023-08-31 |
3-(1,3-thiazol-5-yl)propanoic acid Production Method
Production Method 1
Reaction Conditions
1.1 Reagents: Acetic acid Catalysts: Palladium Solvents: Methanol ; 46 h, 50 psi, rt
Reference
Production Method 2
Reaction Conditions
1.1 Reagents: Lithium bis(trimethylsilyl)amide Solvents: Tetrahydrofuran ; 4 min, 0 °C; 5 min, 0 °C; 15 min
1.2 30 min, 0 °C; 17 h
1.3 Reagents: Water
1.4 Reagents: Sodium borohydride Solvents: Ethanol ; 10 min
1.5 Reagents: Water
1.6 Reagents: Sodium hydroxide Solvents: Tetrahydrofuran , Water ; 5.5 h, rt
1.7 Reagents: Hydrochloric acid Solvents: Water ; pH 1, rt
1.8 Reagents: Hydrogen Catalysts: Palladium Solvents: Ethanol , Ethyl acetate ; 21 h, 1 atm, rt
1.2 30 min, 0 °C; 17 h
1.3 Reagents: Water
1.4 Reagents: Sodium borohydride Solvents: Ethanol ; 10 min
1.5 Reagents: Water
1.6 Reagents: Sodium hydroxide Solvents: Tetrahydrofuran , Water ; 5.5 h, rt
1.7 Reagents: Hydrochloric acid Solvents: Water ; pH 1, rt
1.8 Reagents: Hydrogen Catalysts: Palladium Solvents: Ethanol , Ethyl acetate ; 21 h, 1 atm, rt
Reference
- Beta-lactamase inhibitors, World Intellectual Property Organization, , ,
Production Method 3
Reaction Conditions
1.1 10 min, 170 °C
Reference
- Heterocyclic compounds as pesticides, World Intellectual Property Organization, , ,
3-(1,3-thiazol-5-yl)propanoic acid Raw materials
- (Benzyloxycarbonylmethyl)triphenylphosphonium bromide
- (2E)-3-(1,3-thiazol-5-yl)prop-2-enoic acid
- Thiazole-5-carboxyaldehyde
3-(1,3-thiazol-5-yl)propanoic acid Preparation Products
3-(1,3-thiazol-5-yl)propanoic acid Related Literature
-
Eric Besson,Stéphane Gastaldi,Emily Bloch,Selma Aslan,Hakim Karoui,Olivier Ouari,Micael Hardy Analyst, 2019,144, 4194-4203
-
Jing Yu,Yu-Qi Lyu,Jiapeng Liu,Mohammed B. Effat,Junxiong Wu J. Mater. Chem. A, 2019,7, 17995-18002
-
Hongxia Li,Aikifa Raza,Qiaoyu Ge,Jin-You Lu,TieJun Zhang Soft Matter, 2020,16, 6841-6849
-
Gaurav J. Shah,Eric P.-Y. Chiou,Ming C. Wu,Chang-Jin “CJ” Kim Lab Chip, 2009,9, 1732-1739
-
J. Matthew Kurley,Phillip W. Halstenberg,Abbey McAlister,Stephen Raiman,Richard T. Mayes RSC Adv., 2019,9, 25602-25608
933724-95-9 (3-(1,3-thiazol-5-yl)propanoic acid) Related Products
- 1021910-17-7(4-(1,3-thiazol-5-yl)butan-2-one)
- 933686-34-1(4-(1,3-thiazol-5-yl)butanoic acid)
- 52454-63-4(2-thiazol-5-ylacetic acid)
- 1000527-93-4(3-(1,3-Thiazol-5-yl)propan-1-ol)
- 2229251-42-5(3-(1,3-thiazol-5-yl)pentanedioic acid)
- 2227697-23-4(rac-(1R,3R)-2,2-dimethyl-3-(1,3-thiazol-5-yl)cyclopropane-1-carboxylic acid)
- 1565074-77-2(2-hydroxy-3-(1,3-thiazol-5-yl)propanoic acid)
- 1803603-38-4(3-(1,3-thiazol-5-yl)propanoic acid hydrochloride)
- 60588-57-0(3-(2-Methyl-1,3-thiazol-5-yl)propanoic Acid)
- 2227857-10-3((2R)-4-(1,3-thiazol-5-yl)butan-2-ol)
Recommended suppliers
Yunnanjiuzhen
Gold Member
Audited Supplier
CN Supplier
Bulk
Shandong Feiyang Chemical Co., Ltd
Gold Member
Audited Supplier
CN Supplier
Bulk
Nantong Boya Environmental Protection Technology Co., Ltd
Gold Member
Audited Supplier
CN Supplier
Bulk
PRIBOLAB PTE.LTD
Gold Member
Audited Supplier
CN Supplier
Reagent
Zhejiang Brunova Technology Co., Ltd.
Gold Member
Audited Supplier
CN Supplier
Bulk
