Production Method 1

89204-88-6

93102-96-6

Reaction Conditions

1.1 Reagents: Hydrochloric acid

Reference

Syntheses of 2-mercapto-4-substituted imidazole derivatives with antiinflammatory properties

Maeda, Sadao; Suzuki, Mamoru; Iwasaki, Tameo; Matsumoto, Kazuo; Iwasawa, Yoshio, Chemical & Pharmaceutical Bulletin, 1984, 32(7), 2536-43

Production Method 2

655-15-2

93102-96-6

Reaction Conditions

1.1 Reagents: Hexamethylenetetramine Solvents: Chloroform ;  2 h, 50 °C
1.2 Reagents: Hydrochloric acid Solvents: Ethanol ,  Water ;  4 h, reflux

Reference

Combating fluconazole-resistant fungi with novel β-azole-phenylacetone derivatives

Zhao, Liyu; Sun, Nannan; Tian, Linfeng; Sun, Yin; Chen, Yixuan; et al, European Journal of Medicinal Chemistry, 2019, 183,

Production Method 3

655-15-2

93102-96-6

Reaction Conditions

1.1 Reagents: Hexamethylenetetramine Solvents: Chloroform

Reference

Anomalous reaction of pentafluorophenacyl bromide with hexamethylenetetramine. Structure of the product

Henry, Ronald A.; Hollins, Richard A.; Lowe-Ma, Charlotte; Moore, Donald W.; Nissan, Robin A., Journal of Organic Chemistry, 1990, 55(6), 1796-801

Production Method 4

655-15-2

93102-96-6

Reaction Conditions

1.1 Reagents: Hexamethylenetetramine Solvents: Dichloromethane ;  15 h, rt
1.2 Reagents: Hydrochloric acid Solvents: Ethanol ;  72 h, rt

Reference

An approach to the synthesis of 4-aryl and 5-aryl substituted thiazole-2(3H)-thiones employing flow processing

Balti, Monaem; Miller, Shelli A.; Efrit, Mohamed Lotfi; Leadbeater, Nicholas E., RSC Advances, 2016, 6(76), 72165-72169

Production Method 5

655-15-2

93102-96-6

Reaction Conditions

1.1 Reagents: Hexamethylenetetramine Solvents: Chloroform ;  2 h, 50 °C
1.2 Reagents: Hydrochloric acid Solvents: Ethanol ,  Water ;  2 h, rt → reflux

Reference

Double C-S bond formation via multiple Csp3-H bond cleavage: synthesis of 4-hydroxythiazoles from amides and elemental sulfur under metal-free conditions

Chen, Liang; Xuchen, Xinyu; Wang, Fei; Yang, Yuan; Deng, Guobo; et al, Organic & Biomolecular Chemistry, 2021, 19(46), 10068-10072

Production Method 6

655-15-2

93102-96-6

Reaction Conditions

1.1 Reagents: Hexamethylenetetramine Solvents: Chloroform ;  50 °C
1.2 Reagents: Hydrochloric acid Solvents: Ethanol ,  Water ;  reflux

Reference

Design, synthesis and evaluation of novel 5-phenylthiophene derivatives as potent fungicidal of Candida albicans and antifungal reagents of fluconazole-resistant fungi

Yin, Wenbo; Zhang, Yuxin; Cui, Hengxian; Jiang, Hong; Liu, Lei; et al, European Journal of Medicinal Chemistry, 2021, 225,

Production Method 7

655-15-2

93102-96-6

Reaction Conditions

1.1 Reagents: Hexamethylenetetramine Solvents: Chloroform ;  rt; 15 h, rt
1.2 Reagents: Hydrochloric acid Solvents: Ethanol ,  Water ;  96 h, rt

Reference

New antipsychotic agents with serotonin and dopamine antagonist properties based on a pyrrolo[2,1-b][1,3]benzothiazepine structure

Campiani, Giuseppe; Nacci, Vito; Bechelli, Susanna; Ciani, Silvia M.; Garofalo, Antonio; et al, Journal of Medicinal Chemistry, 1998, 41(20), 3763-3772

2-Amino-1-(2-fluorophenyl)ethanone hydrochloride Raw materials

• 4-Oxazolecarboxylic acid, 5-(2-fluorophenyl)-, methyl ester
• 2-Bromo-2’-fluoroacetophenone

2-Amino-1-(2-fluorophenyl)ethanone hydrochloride Preparation Products

• 2-Amino-1-(2-fluorophenyl)ethanone hydrochloride (93102-96-6)

• 1. Excitable dynamics in the bromate–sulfite–ferrocyanide reaction
  J. Zagora,M. Vosla?,L. Schreiberová,I. Schreiber Phys. Chem. Chem. Phys., 2002,4, 1284-1291
• 2. Excellent lithium ion storage property of porous MnCo2O4 nanorods?
  Peiyuan Zeng,Xiaoxiao Wang,Ming Ye,Qiuyang Ma,Jianwen Li,Wanwan Wang,Baoyou Geng,Zhen Fang RSC Adv., 2016,6, 23074-23084
• 3. Emerging enantiomeric resolution materials with homochiral nano-fabrications
  Ji-Ping Wei Nanoscale, 2015,7, 11815-11832
• 4. Enantio- & chemo-selective preparation of enantiomerically enriched aliphatic nitro alcohols using Candida parapsilosis ATCC 7330
  Sowmyalakshmi Venkataraman RSC Adv., 2015,5, 73807-73813
• 5. Evidence for the intrinsic nature of band-gap states electrochemically observed on atomically flat TiO2(110) surfaces?
  Shintaro Takata,Yoshihiro Miura Phys. Chem. Chem. Phys., 2014,16, 24784-24789

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