Production Method 1

1421517-96-5

925890-48-8

Reaction Conditions

1.1 Reagents: Tetrabutylammonium bromide Solvents: Dichloromethane ;  10 min, rt
1.2 Reagents: p-Toluenesulfonic anhydride ;  overnight, rt

Reference

Regioselective Bromination of Fused Heterocyclic N-Oxides

Wengryniuk, Sarah E.; Weickgenannt, Andreas; Reiher, Christopher; Strotman, Neil A.; Chen, Ke; et al, Organic Letters, 2013, 15(4), 792-795

1-Bromo-4-chloroisoquinoline Raw materials

• Isoquinoline, 4-chloro-, 2-oxide

1-Bromo-4-chloroisoquinoline Preparation Products

• 1-Bromo-4-chloroisoquinoline (925890-48-8)

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• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Isoquinolines and derivatives Isoquinolines and derivatives
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Isoquinolines and derivatives

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