Production Method 1

5508-58-7

919120-75-5

955428-65-6

1020673-18-0

869807-57-8

4176-97-0

1020673-19-1

1262950-29-7

42895-58-9

Reaction Conditions

1.1 Solvents: Water ;  96 h, 28 °C

Reference

Cytotoxic biotransformed products from andrographolide by Rhizopus stolonifer ATCC 12939

He, Xiangjiu; et al, Journal of Molecular Catalysis B: Enzymatic, 2010, 62(3-4), 242-247

3-[(1E)-2-[(1R,4aS,5R,8aR)-Decahydro-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-6-oxo-1-naphthalenyl]ethenyl]-2(5H)-furanone Raw materials

• Andrographolide

3-[(1E)-2-[(1R,4aS,5R,8aR)-Decahydro-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-6-oxo-1-naphthalenyl]ethenyl]-2(5H)-furanone Preparation Products

• 3-Oxoandrographolide (955428-65-6)
• 12(S),13(S)-12-hydroxyandrographolide (1020673-18-0)
• Andropanolide (869807-57-8)
• 14-Deoxyandrographolide (4176-97-0)
• 12(R),13(R)-12-hydroxyandrographolide (1020673-19-1)
• 2(3H)-Furanone, 3-[2-[(1R,4aS,5R,8aS)-decahydro-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-6-oxo-1-naphthalenyl]ethylidene]dihydro-4-hydroxy-, (3Z,4S)- (1262950-29-7)
• 3-[(1E)-2-[(1R,4aS,5R,8aR)-Decahydro-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-6-oxo-1-naphthalenyl]ethenyl]-2(5H)-furanone (919120-75-5)
• 14-Deoxy-11,12-didehydroandrographolide (42895-58-9)

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• Solvents and Organic Chemicals Organic Compounds Lipids and lipid-like molecules Prenol lipids Diterpene lactones
• Solvents and Organic Chemicals Organic Compounds Lipids and lipid-like molecules Prenol lipids Terpene lactones Diterpene lactones

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