Production Method 1

25177-85-9

91142-58-4

Reaction Conditions

1.1 Reagents: Lithium diisopropylamide Solvents: Tetrahydrofuran ;  < 0 °C; 45 min, < 0 °C
1.2 0 °C → rt; 1 h, rt
1.3 Reagents: Ammonium chloride Solvents: Water ;  rt

Reference

Catalytic Decarboxylative Radical Sulfinylation

He, Shi-Hui; Chen, Guang-Le; Gong, Xing-Yu; Ao, Gui-Zhen; Liu, Feng, Journal of Organic Chemistry, 2023, 88(11), 6671-6681

Production Method 2

91142-58-4

Reaction Conditions

Reference

Secondary fungal metabolites and their biological activities. IV. Synthesis of compounds with structural similarities to the toxic metabolites of the pathogenic fungus Heterobasidion annosum and investigation of their antibiotic activities

Sonnenbichler, Johann; Dietrich, Juergen; Schaefer, Wolfram; Zetl, Isolde, Biological Chemistry Hoppe-Seyler, 1993, 374(11), 1047-55

Production Method 3

58920-75-5

91142-58-4

Reaction Conditions

1.1 Reagents: Lithium hydroxide ,  Hydrogen peroxide Solvents: Methanol ,  Water ;  20 min, 0 °C
1.2 Solvents: Methanol ;  30 min, 0 °C; 30 min, rt
1.3 Reagents: Sodium hydroxide Solvents: Diethyl ether ,  Water ;  rt
1.4 Reagents: Hydrochloric acid Solvents: Water ;  acidified, rt

Reference

Mechanism and regioselectivity of the anionic oxidative rearrangement of 1,3-diketones towards all-carbon quaternary carboxylates

Bratt, Emma; Suarez-Pantiga, Samuel; Johansson, Magnus J.; Mendoza, Abraham, Chemical Communications (Cambridge, 2019, 55(60), 8844-8847

Production Method 4

2177-47-1

91142-58-4

Reaction Conditions

1.1 Reagents: Triethanolamine Catalysts: Tetraethylammonium iodide Solvents: Dimethylformamide ;  8 h, 1 atm, rt

Reference

Harnessing Applied Potential: Selective β-Hydrocarboxylation of Substituted Olefins

Alkayal, Anas; Tabas, Volodymyr; Montanaro, Stephanie; Wright, Iain A. ; Malkov, Andrei V. ; et al, Journal of the American Chemical Society, 2020, 142(4), 1780-1785

Production Method 5

5669-14-7

91142-58-4

Reaction Conditions

1.1 Reagents: Silver carbonate ,  Oxygen ,  Pyridinium, 1-fluoro-2,4,6-trimethyl-, tetrafluoroborate(1-) (1:1) Catalysts: Palladium(2+), tetrakis(acetonitrile)-, (SP-4-1)-, tetrafluoroborate(1-) (1:2) Solvents: 1,1,1,3,3,3-Hexafluoro-2-propanol ;  3 min, rt; 12 h, rt → 90 °C; 90 °C → rt
1.2 Reagents: Formic acid ;  rt

Reference

Rapid Construction of Tetralin, Chromane, and Indane Motifs via Cyclative C-H/C-H Coupling: Four-Step Total Synthesis of (±)-Russujaponol F

Zhuang, Zhe ; Herron, Alastair N. ; Liu, Shuang; Yu, Jin-Quan, Journal of the American Chemical Society, 2021, 143(2), 687-692

Production Method 6

5669-14-7

91142-58-4

Reaction Conditions

1.1 Reagents: Silver carbonate ,  Pyridinium, 1-fluoro-2,4,6-trimethyl-, tetrafluoroborate(1-) (1:1) Catalysts: Palladium(2+), tetrakis(acetonitrile)-, (SP-4-1)-, tetrafluoroborate(1-) (1:2) Solvents: 1,1,1,3,3,3-Hexafluoro-2-propanol ;  3 min, rt; 12 h, rt → 90 °C; 90 °C → rt
1.2 Reagents: Formic acid ;  rt

Reference

Rapid construction of tetralin, chromane, and indane motifs via cyclative C-H/C-H coupling: four-step total synthesis of (±)- russujaponol F

Zhuang, Zhe; Herron, Alastair N.; Liu, Shuang; Yu, Jin-Quan, ChemRxiv, 2020, 1, 1-6

Production Method 7

91142-58-4

Reaction Conditions

Reference

Substituted imidazole derivatives and their use

, European Patent Organization, , ,

2-methyl-2,3-dihydro-1H-indene-2-carboxylic acid Raw materials

• 2,3-Dihydro-1H-indene-2-carboxylic acid
• 2,2-Dimethyl-3-phenylpropanoic acid
• 2-Methyl-1H-indene
• 2,2-diacetyl-indane

2-methyl-2,3-dihydro-1H-indene-2-carboxylic acid Preparation Products

• 2-methyl-2,3-dihydro-1H-indene-2-carboxylic acid (91142-58-4)

• 1. Excitonic and vibrational coherence in artificial photosynthetic systems studied by negative-time ultrafast laser spectroscopy
  Dongjia Han,Bing Xue,Juan Du,Tomohiro Miyatake,Hitoshi Tamiaki,Xin Xing,Wei Yuan,Yanyan Li Phys. Chem. Chem. Phys., 2016,18, 24252-24260
• 2. Evolution of cellulose into flexible conductive green electronics: a smart strategy to fabricate sustainable electrodes for supercapacitors
  Tengfei Yu,Yuehan Wu,Wei Li,Bin Li RSC Adv., 2014,4, 34134-34143
• 3. Embedding cyclic nitrone in mesoporous silica particles for EPR spin trapping of superoxide and other radicals?
  Eric Besson,Stéphane Gastaldi,Emily Bloch,Selma Aslan,Hakim Karoui,Olivier Ouari,Micael Hardy Analyst, 2019,144, 4194-4203
• 4. Fe3O4@SiO2 core–shell nanoparticles for biomedical purposes: adverse effects on blood cells?
  C. Achilli,G. F. Guidetti,A. Ciana,D. Capsoni,G. Minetti Biomater. Sci., 2016,4, 1417-1421
• 5. Distinguishing between polymorphic forms of linezolid by solid-phase electronic and vibrational circular dichroism?
  Jadwiga Frelek,Marcin Górecki,Marta ?aszcz,Agata Suszczyńska,Elemér Vass,Wojciech J. Szczepek Chem. Commun., 2012,48, 5295-5297

• 25177-85-9(2,3-Dihydro-1H-indene-2-carboxylic acid)
• 82054-55-5(1H-INDENE-2-CARBOXYLIC ACID, 2,3-DIHYDRO-2-(2-PHENYLETHYL)-)
• 154866-44-1(1H-Indene-2-carboxylic acid, 2,3-dihydro-1,1,3,3-tetramethyl-)
• 2150245-64-8(2-(2,3-dihydro-1H-inden-2-yl)butanoic acid)
• 1267533-93-6(1',3'-dihydrospiro[cyclopropane-1,2'-indene]-2-carboxylic acid)
• 2229602-19-9(3-(2,3-dihydro-1H-inden-2-yl)-2,2-dimethylpropanoic acid)
• 1367026-91-2(1,1-dimethylindane-2-carboxylic acid)
• 113313-03-4(1H-Indene-2-carboxylic acid, 2-[2-(2,5-dimethylphenyl)ethyl]-2,3-dihydro-)
• 1507898-29-4(2-(2,3-dihydro-1H-inden-2-yl)propanoic acid)
• 1781070-97-0(2-(2,3-dihydro-1H-inden-2-yl)-2-methylpropanoic acid)