Fe3O4@SiO2 core–shell nanoparticles for biomedical purposes: adverse effects on blood cells?

Biomaterials Science Pub Date: 2016-08-12 DOI: 10.1039/C6BM00374E

Abstract

Magnetite nanoparticles coated with silica, obtained by a sol–gel process in the reverse micelle microemulsion, were characterized and homogeneously suspended in water in order to assay their biocompatibility toward blood cells, in view of a potential medical use of this material. Their hemolytic, pro-thrombotic and pro-inflammatory properties were observed.

Graphical abstract: Fe3O4@SiO2 core–shell nanoparticles for biomedical purposes: adverse effects on blood cells
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