Production Method 1

909037-18-9

Reaction Conditions

1.1 Catalysts: Nickel Solvents: 1-Propanol ;  60 min, 3 - 18 bar, 160 °C

Reference

Microwave-assisted Raney nickel reduction of bispidinone thioketals to N,N'-dialkylbispidines

Toom, Lauri; Grennberg, Helena; Gogoll, Adolf, Synthesis, 2006, (12), 2064-2068

Production Method 2

23133-37-1

909037-18-9

Reaction Conditions

1.1 Reagents: Acetic acid Solvents: Ethanol ;  7 h, rt → 42 °C; 9 h, 37 - 42 °C
1.2 Reagents: Potassium hydroxide ,  Hydrazine hydrate (1:1) Solvents: Diethylene glycol ;  < 85 °C; 1 h, 80 - 90 °C; 90 °C → 152 °C

Reference

Stereoselective Lithiation and Carboxylation of Boc-Protected Bicyclopyrrolidine: Synthesis of a Key Building Block for HCV Protease Inhibitor Telaprevir

Tanoury, Gerald J.; Chen, Minzhang; Dong, Yong; Forslund, Raymond; Jurkauskas, Valdas; et al, Organic Process Research & Development, 2014, 18(10), 1234-1244

Production Method 3

926276-14-4

909037-18-9

Reaction Conditions

1.1 Reagents: Potassium hydroxide ,  Hydrazine hydrate (1:1) Solvents: Diethylene glycol ;  rt; 16 h, 180 °C

Reference

Investigation of bispidines as the stoichiometric ligand in the two-ligand catalytic asymmetric deprotonation of N-BOC-pyrrolidine

Barker, Graeme; O'Brien, Peter; Campos, Kevin R., ARKIVOC (Gainesville, 2011, (5), 217-229

Production Method 4

926276-14-4

909037-18-9

Reaction Conditions

1.1 Reagents: Potassium hydroxide ,  Hydrazine hydrate (1:1) Solvents: Diethylene glycol ;  rt; 16 h, 180 °C

Reference

Regioselective Lithiation of Silyl Phosphine Sulfides: Asymmetric Synthesis of P-Stereogenic Compounds

Gammon, Jonathan J.; O'Brien, Peter; Kelly, Brian, Organic Letters, 2009, 11(21), 5022-5025

3,7-Dipropyl-3,7-diazabicyclo[3.3.1]nonane Raw materials

• N,N-Dipropyl-9-oxo-bispidine
• 1-propylpiperidin-4-one

3,7-Dipropyl-3,7-diazabicyclo[3.3.1]nonane Preparation Products

• 3,7-Dipropyl-3,7-diazabicyclo[3.3.1]nonane (909037-18-9)

• 1. Emulsifier-free, organotellurium-mediated living radical emulsion polymerization (emulsion TERP) of styrene: poly(dimethylaminoethyl methacrylate) macro-TERP agent?
  Yukiya Kitayama Polym. Chem., 2014,5, 2784-2792
• 2. Excitable dynamics in the bromate–sulfite–ferrocyanide reaction
  J. Zagora,M. Vosla?,L. Schreiberová,I. Schreiber Phys. Chem. Chem. Phys., 2002,4, 1284-1291
• 3. Elusive 2-aminofuran Diels–Alder substrates for a straightforward synthesis of polysubstituted anilines?
  Ana G. Neo,Ana Bornadiego,Jesús Díaz,Stefano Marcaccini,Carlos F. Marcos Org. Biomol. Chem., 2013,11, 6546-6555
• 4. Evolution of cellulose into flexible conductive green electronics: a smart strategy to fabricate sustainable electrodes for supercapacitors
  Tengfei Yu,Yuehan Wu,Wei Li,Bin Li RSC Adv., 2014,4, 34134-34143
• 5. Evolutionary de novo design of phenothiazine derivatives for dye-sensitized solar cells?
  Vishwesh Venkatraman,Marco Foscato,Vidar R. Jensen,Bj?rn K?re Alsberg J. Mater. Chem. A, 2015,3, 9851-9860

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Piperidines Piperidines
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Piperidines

• 58324-99-5(3,7-Diazabicyclo[3.3.1]nonane, 3-methyl-)
• 81310-56-7(3-[(piperidin-1-yl)methyl]piperidine)
• 90203-05-7(N,N-Dimethyl-1-piperidin-3-ylmethanamine)
• 845290-58-6(2-Methyl-2,8-diazaspiro5.5undecane)
• 90961-45-8(3,7-Diazabicyclo[3.3.1]nonane,3,7-dibutyl-9,9-dimethyl-)
• 500565-32-2(3-Piperidinemethanamine,N,N,1-trimethyl-(9CI))
• 639078-61-8(N-methyl-1-(1-methylpiperidin-3-yl)methanamine)
• 169177-35-9(1,3,5-trimethyl-3,7-diazabicyclo3.3.1nonane)
• 75936-99-1({1-azabicyclo[2.2.2]octan-3-yl}methanamine)
• 102459-02-9(1-(1-Ethylpiperidin-3-yl)methanamine)