Cas no 90203-05-7 (N,N-Dimethyl-1-piperidin-3-ylmethanamine)

N,N-Dimethyl-1-piperidin-3-ylmethanamine is a tertiary amine compound featuring a piperidine core substituted with a dimethylaminomethyl group at the 3-position. This structure imparts unique reactivity and versatility, making it valuable as an intermediate in organic synthesis and pharmaceutical applications. Its tertiary amine functionality enhances nucleophilicity, facilitating its use in alkylation and condensation reactions. The piperidine scaffold contributes to conformational rigidity, which can be advantageous in drug design for modulating bioavailability and target binding. The compound's balanced lipophilicity and basicity further support its utility in medicinal chemistry, particularly for developing CNS-active agents or ligands for receptor studies. Proper handling under inert conditions is recommended due to potential sensitivity to air or moisture.
N,N-Dimethyl-1-piperidin-3-ylmethanamine structure
90203-05-7 structure
Product Name:N,N-Dimethyl-1-piperidin-3-ylmethanamine
CAS No:90203-05-7
MF:C8H18N2
MW:142.241921901703
MDL:MFCD05215128
CID:798121
PubChem ID:16768076
Update Time:2025-10-18

N,N-Dimethyl-1-piperidin-3-ylmethanamine Chemical and Physical Properties

Names and Identifiers

    • N,N-Dimethyl-(piperidin-3-yl)methanamine
    • 3-Piperidinemethanamine,N,N-dimethyl-
    • N,N-Dimethyl(3-piperidinyl)methanaminedihydrochloride
    • N,N-dimethyl(piperidin-3-yl)methanamine
    • N,N-Dimethyl-1-piperidin-3-ylmethanamine
    • N,N-DIMETHYL-3-PIPERIDINEMETHANAMINE
    • N,N-DiMethyl-3-piperidineMethylaMine
    • N,N-dimethyl-1-(3-piperidinyl)methanamine
    • N,N-Dimethyl-(R)-(piperidin-3-yl)methanamine
    • MFCD05215128
    • DTXSID701009248
    • N,N-dimethyl-1-piperidin-3-yl-methanamine
    • dimethyl[(piperidin-3-yl)methyl]amine
    • EN300-35742
    • n,n-dimethyl-1-(piperidin-3-yl)methanamine
    • AKOS000123482
    • 3-(dimethylamino-methyl)-piperidine
    • FT-0645557
    • AKOS016341120
    • A860884
    • N,N-Dimethyl-3-piperidinemethylamine,95%
    • A843467
    • FT-0646690
    • SCHEMBL1914232
    • BS-38621
    • 3-(dimethylaminomethyl)piperidine
    • N,N-Dimethyl-1-(3-piperidyl)methanamine
    • SY274070
    • 90203-05-7
    • BB 0220184
    • CS-0181023
    • SB42236
    • QOVQVKFKBHWTAA-UHFFFAOYSA-N
    • (R)-N,N-Dimethyl-3-piperidinemethanamine 2HCl
    • 254905-65-2
    • dimethyl({[(3R)-piperidin-3-yl]methyl})amine
    • ALBB-036771
    • N,N-dimethyl-1-[(3S)-3-piperidyl]methanamine
    • dimethyl(piperidin-3-ylmethyl)amine
    • MDL: MFCD05215128
    • Inchi: 1S/C8H18N2/c1-10(2)7-8-4-3-5-9-6-8/h8-9H,3-7H2,1-2H3
    • InChI Key: QOVQVKFKBHWTAA-UHFFFAOYSA-N
    • SMILES: N1CCCC(CN(C)C)C1

Computed Properties

  • Exact Mass: 142.14700
  • Monoisotopic Mass: 142.146998583g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 2
  • Complexity: 91.3
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 1
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: 0.6
  • Topological Polar Surface Area: 15.3?2

Experimental Properties

  • Density: 0.868
  • Boiling Point: 178.775°C at 760 mmHg
  • Flash Point: 51.809°C
  • Refractive Index: 1.451
  • PSA: 15.27000
  • LogP: 0.87640

N,N-Dimethyl-1-piperidin-3-ylmethanamine Security Information

N,N-Dimethyl-1-piperidin-3-ylmethanamine Customs Data

  • HS CODE:2933399090
  • Customs Data:

    China Customs Code:

    2933399090

    Overview:

    2933399090. Other compounds with non fused pyridine rings in structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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Additional information on N,N-Dimethyl-1-piperidin-3-ylmethanamine

N,N-Dimethyl-1-piperidin-3-ylmethanamine: A Comprehensive Overview of CAS No. 90203-05-7

N,N-Dimethyl-1-piperidin-3-ylmethanamine (CAS No. 90203-05-7) is a versatile organic compound with a unique structure that has garnered significant attention in the fields of medicinal chemistry and pharmaceutical research. This compound, characterized by its piperidine ring and dimethylamino substituents, exhibits a range of biological activities that make it a valuable candidate for various therapeutic applications.

The chemical structure of N,N-Dimethyl-1-piperidin-3-ylmethanamine consists of a piperidine ring with a methylene bridge connecting the 3-position of the ring to an N,N-dimethylamino group. This configuration imparts specific physical and chemical properties that are crucial for its biological interactions. The compound is typically synthesized through multi-step processes involving the functionalization of piperidine derivatives and subsequent coupling reactions to introduce the desired substituents.

Recent studies have highlighted the potential of N,N-Dimethyl-1-piperidin-3-ylmethanamine in various therapeutic areas. One notable application is its use as a modulator of neurotransmitter systems, particularly in the central nervous system (CNS). Research has shown that this compound can interact with serotonin and dopamine receptors, making it a promising candidate for the treatment of neurological disorders such as depression, anxiety, and Parkinson's disease.

In addition to its potential in CNS disorders, N,N-Dimethyl-1-piperidin-3-ylmethanamine has also been investigated for its anti-inflammatory properties. Studies have demonstrated that it can inhibit the production of pro-inflammatory cytokines and reduce oxidative stress, which are key factors in the pathogenesis of inflammatory diseases such as arthritis and inflammatory bowel disease (IBD). These findings suggest that the compound may have broad therapeutic applications beyond its initial focus on neurological conditions.

The pharmacokinetic profile of N,N-Dimethyl-1-piperidin-3-ylmethanamine has been extensively studied to understand its behavior in biological systems. It has been found to exhibit good oral bioavailability and favorable pharmacokinetic properties, making it suitable for both preclinical and clinical development. The compound's stability under physiological conditions and its ability to cross the blood-brain barrier further enhance its potential as a therapeutic agent.

Clinical trials involving N,N-Dimethyl-1-piperidin-3-ylmethanamine have shown promising results in terms of safety and efficacy. Early-phase trials have demonstrated that the compound is well-tolerated by patients, with minimal adverse effects reported. These findings have paved the way for more advanced clinical studies to evaluate its therapeutic potential in larger patient populations.

The mechanism of action of N,N-Dimethyl-1-piperidin-3-ylmethanamine is an area of ongoing research. Current evidence suggests that it exerts its effects through multiple pathways, including modulation of neurotransmitter receptors, inhibition of inflammatory mediators, and regulation of intracellular signaling cascades. Understanding these mechanisms in detail will be crucial for optimizing the compound's therapeutic utility and developing targeted treatment strategies.

In conclusion, N,N-Dimethyl-1-piperidin-3-ylmethanamine (CAS No. 90203-05-7) represents a promising compound with diverse biological activities and therapeutic potential. Its unique chemical structure and favorable pharmacological properties make it an attractive candidate for further research and development in various medical fields. As ongoing studies continue to unravel its mechanisms of action and clinical applications, this compound is poised to play a significant role in advancing our understanding and treatment of complex diseases.

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