- Design and synthesis of a hybrid series of potent and selective agonists of α7 nicotinic acetylcholine receptorNencini, Arianna; Castaldo, Cristiana; Comery, Thomas A.; Dunlop, John; Genesio, Eva; et al, European Journal of Medicinal Chemistry, 2014, 78, 401-418
Cas no 902837-26-7 (tert-Butyl 4-pyrrolidin-1-ylpiperidine-1-carboxylate)
902837-26-7 structure
Product Name:tert-Butyl 4-pyrrolidin-1-ylpiperidine-1-carboxylate
CAS No:902837-26-7
MF:C14H26N2O2
MW:254.368443965912
CID:803203
PubChem ID:42553448
Update Time:2024-10-26
tert-Butyl 4-pyrrolidin-1-ylpiperidine-1-carboxylate Chemical and Physical Properties
Names and Identifiers
-
- tert-Butyl 4-(pyrrolidin-1-yl)piperidine-1-carboxylate
- 1-Piperidinecarboxylic acid, 4-(1-pyrrolidinyl)-, 1,1- dimethylethyl ester
- 4-PYRROLIDIN-1-YL-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
- tert-butyl 4-pyrrolidin-1-ylpiperidine-1-carboxylate
- tert-butyl 4-pyrrolidinylpiperidinecarboxylate
- 1,1-Dimethylethyl 4-(1-pyrrolidinyl)-1-piperidinecarboxylate (ACI)
- 1-Boc-4-(1-pyrrolidinyl)piperidine
- 1-Piperidinecarboxylicacid,4-(1-pyrrolidinyl)-,1,1-dimethylethyl ester
- TS-03437
- DTXSID10654811
- CS-0002013
- CLB83726
- AKOS009461505
- 1-Piperidinecarboxylic acid, 4-(1-pyrrolidinyl)-, 1,1-dimethylethyl ester
- SCHEMBL17128329
- SDCCGSBI-0663205.P001
- tert-butyl4-(pyrrolidin-1-yl)piperidine-1-carboxylate
- 902837-26-7
- 1-Piperidinecarboxylicacid, 4-(1-pyrrolidinyl)-, 1,1-dimethylethyl ester
- tert-Butyl 4-pyrrolidin-1-ylpiperidine-1-carboxylate
-
- MDL： MFCD08056347
- Inchi： 1S/C14H26N2O2/c1-14(2,3)18-13(17)16-10-6-12(7-11-16)15-8-4-5-9-15/h12H,4-11H2,1-3H3
- InChI Key： KJJXFFZNVKNQAC-UHFFFAOYSA-N
- SMILES： O=C(N1CCC(N2CCCC2)CC1)OC(C)(C)C
Computed Properties
- Exact Mass: 254.19900
- Monoisotopic Mass: 254.199
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 18
- Rotatable Bond Count: 4
- Complexity: 285
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 32.8A^2
- XLogP3: 2.2
Experimental Properties
- Density: 1.068
- Boiling Point: 333.027°C at 760 mmHg
- Flash Point: 155.209°C
- Refractive Index: 1.512
- PSA: 32.78000
- LogP: 2.35750
tert-Butyl 4-pyrrolidin-1-ylpiperidine-1-carboxylate Customs Data
- HS CODE：2933990090
- Customs Data：
China Customs Code:
2933990090Overview:
2933990090. Other heterocyclic compounds containing only nitrogen heteroatoms. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%
Declaration elements:
Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date
Summary:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
tert-Butyl 4-pyrrolidin-1-ylpiperidine-1-carboxylate Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Chemenu | CM179694-1g |
tert-Butyl 4-pyrrolidin-1-ylpiperidine-1-carboxylate |
902837-26-7 | 97% | 1g |
$608 | 2021-08-05 | |
| TRC | T065645-500mg |
tert-Butyl 4-pyrrolidin-1-ylpiperidine-1-carboxylate |
902837-26-7 | 500mg |
$ 760.00 | 2022-06-03 | ||
| TRC | T065645-1000mg |
tert-Butyl 4-pyrrolidin-1-ylpiperidine-1-carboxylate |
902837-26-7 | 1g |
$ 1260.00 | 2022-06-03 | ||
| Alichem | A109008208-1g |
tert-Butyl 4-(pyrrolidin-1-yl)piperidine-1-carboxylate |
902837-26-7 | 97% | 1g |
$695.50 | 2023-08-31 | |
| Alichem | A109008208-5g |
tert-Butyl 4-(pyrrolidin-1-yl)piperidine-1-carboxylate |
902837-26-7 | 97% | 5g |
$766.26 | 2023-08-31 | |
| Chemenu | CM179694-1g |
tert-Butyl 4-pyrrolidin-1-ylpiperidine-1-carboxylate |
902837-26-7 | 97% | 1g |
$314 | 2024-07-20 | |
| SHANG HAI HAO HONG Biomedical Technology Co., Ltd. | 1072069-1g |
1-Piperidinecarboxylic acid, 4-(1-pyrrolidinyl)-, 1,1-dimethylethyl ester |
902837-26-7 | 97% | 1g |
￥3066.00 | 2024-04-26 | |
| A2B Chem LLC | AI60457-250mg |
tert-Butyl 4-(pyrrolidin-1-yl)piperidine-1-carboxylate |
902837-26-7 | 98% | 250mg |
$120.00 | 2024-05-20 | |
| A2B Chem LLC | AI60457-1g |
tert-Butyl 4-(pyrrolidin-1-yl)piperidine-1-carboxylate |
902837-26-7 | 98% | 1g |
$412.00 | 2024-05-20 | |
| Crysdot LLC | CD11021279-1g |
tert-Butyl 4-(pyrrolidin-1-yl)piperidine-1-carboxylate |
902837-26-7 | 97% | 1g |
$644 | 2024-07-19 |
tert-Butyl 4-pyrrolidin-1-ylpiperidine-1-carboxylate Production Method
Production Method 1
Reaction Conditions
1.1 Reagents: Sodium hydroxide Solvents: Dichloromethane , Water ; rt → 0 °C
1.2 0 °C; 0 °C → rt; 2 d, rt
1.3 Solvents: 1,4-Dioxane ; 6 h, 60 °C
1.4 Reagents: Trifluoroacetic acid Solvents: Dichloromethane ; overnight, rt
1.2 0 °C; 0 °C → rt; 2 d, rt
1.3 Solvents: 1,4-Dioxane ; 6 h, 60 °C
1.4 Reagents: Trifluoroacetic acid Solvents: Dichloromethane ; overnight, rt
Reference
tert-Butyl 4-pyrrolidin-1-ylpiperidine-1-carboxylate Raw materials
- 1H-Pyrazole-1-carboxylic acid, 5-amino-3-(4-methoxyphenyl)-, 1,1-dimethylethyl ester
- Isopropenyl Chloroformate (stabilized with 100ppm BHT)
- 4-(Pyrrolidinyl)piperidine
tert-Butyl 4-pyrrolidin-1-ylpiperidine-1-carboxylate Preparation Products
tert-Butyl 4-pyrrolidin-1-ylpiperidine-1-carboxylate Related Literature
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1. Fatty acid eutectic mixtures and derivatives from non-edible animal fat as phase change materials?Pau Gallart-Sirvent,Marc Martín,Gemma Villorbina,Mercè Balcells,Aran Solé,Luisa F. Cabeza,Ramon Canela-Garayoa RSC Adv., 2017,7, 24133-24139
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Yong Ping Huang,Tao Tao,Zheng Chen,Wei Han,Ying Wu,Chunjiang Kuang,Shaoxiong Zhou,Ying Chen J. Mater. Chem. A, 2014,2, 18831-18837
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Ana G. Neo,Ana Bornadiego,Jesús Díaz,Stefano Marcaccini,Carlos F. Marcos Org. Biomol. Chem., 2013,11, 6546-6555
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