Cas no 57933-83-2 (Isopropenyl Chloroformate (stabilized with 100ppm BHT))

Isopropenyl Chloroformate (stabilized with 100ppm BHT) is a highly reactive acylating agent used in organic synthesis, particularly for introducing the isopropenyloxycarbonyl (IPOC) protecting group. The inclusion of 100ppm BHT (butylated hydroxytoluene) enhances its stability by inhibiting premature polymerization, ensuring consistent performance during storage and handling. This compound is valued for its efficiency in peptide coupling, esterification, and other acyl transfer reactions due to its high reactivity with nucleophiles. Its liquid form facilitates precise dispensing, while the stabilization allows for extended shelf life under recommended storage conditions. Suitable for use in controlled laboratory environments, it requires careful handling due to its moisture sensitivity and corrosive nature.
Isopropenyl Chloroformate (stabilized with 100ppm BHT) structure
57933-83-2 structure
Product Name:Isopropenyl Chloroformate (stabilized with 100ppm BHT)
CAS No:57933-83-2
MF:C4H5ClO2
MW:120.53430056572
CID:57215
PubChem ID:93846
Update Time:2025-06-15

Isopropenyl Chloroformate (stabilized with 100ppm BHT) Chemical and Physical Properties

Names and Identifiers

    • Isopropenyl chloroformate
    • prop-1-en-2-yl carbonochloridate
    • Isobutyl acetate
    • Isopropenyl chloroformate, stabilized
    • AKOS015848594
    • NS00033812
    • UNII-JH4WS74VHF
    • DTXSID10206637
    • MFCD00037083
    • BB 0260089
    • prop-1-en-2-yl chloroformate
    • FT-0627461
    • 57933-83-2
    • JH4WS74VHF
    • SCHEMBL27786
    • 1-METHYLETHENYL CARBONOCHLORIDATE
    • Carbonochloridic acid, 1-methylethenyl ester
    • EINECS 261-018-4
    • Isopropenyl Chloroformate (stabilized with 100ppm BHT)
    • chlorocarbonic acid isopropenyl ester
    • isopropenylchloro-formate
    • isopropenylchloroformate
    • Prop-1-en-2-yl Carbonochloridate; 1-Methylethenyl Ester Carbonochloridic Acid;
    • DB-360588
    • DTXCID40129128
    • Inchi: 1S/C4H5ClO2/c1-3(2)7-4(5)6/h1H2,2H3
    • InChI Key: AMMGCGVWJMRTQI-UHFFFAOYSA-N
    • SMILES: ClC(=O)OC(=C)C

Computed Properties

  • Exact Mass: 119.99800
  • Monoisotopic Mass: 119.997807
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 7
  • Rotatable Bond Count: 2
  • Complexity: 97.9
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: 2
  • Topological Polar Surface Area: 26.3

Experimental Properties

  • Color/Form: Colorless liquid with irritating odor
  • Density: 1.103
  • Melting Point: No data available
  • Boiling Point: 95-97 oC
  • Flash Point: 10 oC
  • Refractive Index: 1.413-1.415
  • Water Partition Coefficient: React
  • PSA: 26.30000
  • LogP: 1.89540
  • Solubility: Soluble in benzene\Ether,Insoluble in water,Encounter water\ethanoldecomposition.
  • Vapor Pressure: No data available

Isopropenyl Chloroformate (stabilized with 100ppm BHT) Security Information

Isopropenyl Chloroformate (stabilized with 100ppm BHT) Customs Data

  • HS CODE:2915900090
  • Customs Data:

    China Customs Code:

    2915900090

    Overview:

    2915900090. Other saturated acyclic monocarboxylic acids and their anhydrides(Acyl halide\Peroxygenation)Chemicals\Peroxy acid and its halogenation\nitrification\sulfonation\Nitrosative derivative. VAT:17.0%. Tax refund rate:9.0%. Regulatory conditions:AB(Customs clearance form for Inbound Goods,Customs clearance form for outbound goods). MFN tariff:5.5%. general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Regulatory conditions:

    A.Customs clearance form for Inbound Goods
    B.Customs clearance form for outbound goods

    Inspection and quarantine category:

    R.Sanitary supervision and inspection of imported food
    S.Sanitary supervision and inspection of exported food
    M.Import commodity inspection
    N.Export commodity inspection

    Summary:

    2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%

Isopropenyl Chloroformate (stabilized with 100ppm BHT) Pricemore >>

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Additional information on Isopropenyl Chloroformate (stabilized with 100ppm BHT)

Comprehensive Overview of Isopropenyl Chloroformate (CAS No. 57933-83-2) Stabilized with BHT

Isopropenyl Chloroformate (CAS No. 57933-83-2), a specialized chemical compound stabilized with 100ppm BHT (Butylated Hydroxytoluene), is widely recognized for its versatility in organic synthesis and industrial applications. This compound, often referred to as stabilized Isopropenyl Chloroformate or BHT-stabilized Chloroformate, plays a critical role in the production of polymers, pharmaceuticals, and agrochemicals. Its unique reactivity and stability make it a preferred choice for researchers and manufacturers alike.

One of the most frequently searched questions about Isopropenyl Chloroformate revolves around its synthesis process and handling precautions. The compound is synthesized through the reaction of isopropenol with phosgene, followed by stabilization with BHT to enhance shelf life and prevent unwanted polymerization. Users often inquire about storage conditions, with recommendations emphasizing cool, dry environments away from direct sunlight to maintain efficacy. The addition of BHT as a stabilizer addresses common concerns about degradation over time, ensuring consistent performance in lab and industrial settings.

In recent years, the demand for high-purity Isopropenyl Chloroformate has surged, driven by advancements in green chemistry and sustainable manufacturing. Researchers are exploring its use in biodegradable polymer production, aligning with global trends toward eco-friendly materials. Searches for Isopropenyl Chloroformate substitutes or alternatives have also increased, reflecting the industry's focus on safer and more sustainable reagents. However, its unmatched efficiency in carbamate and carbonate formation keeps it irreplaceable in many applications.

The compound's role in pharmaceutical intermediates is another hot topic. Isopropenyl Chloroformate is instrumental in synthesizing active pharmaceutical ingredients (APIs), particularly in peptide coupling and protecting group chemistry. Queries about its reactivity with amino acids or compatibility with other reagents are common among chemists optimizing synthetic routes. Its stabilized form ensures minimal side reactions, a key consideration for high-yield processes.

From an industrial perspective, Isopropenyl Chloroformate is valued for its scalability and cost-effectiveness. Manufacturers frequently search for bulk suppliers or technical specifications to meet large-scale production needs. The compound's compatibility with continuous flow chemistry systems has also garnered attention, as industries adopt automated synthesis to improve efficiency. Discussions around regulatory compliance and safety data sheets (SDS) further highlight its responsible use in global supply chains.

In summary, Isopropenyl Chloroformate (CAS No. 57933-83-2) remains a cornerstone in modern chemistry, bridging academic research and industrial innovation. Its stabilization with BHT addresses stability concerns, while its applications in sustainable chemistry and pharmaceuticals keep it at the forefront of scientific inquiry. As users continue to explore its potential, this compound will undoubtedly play a pivotal role in shaping future chemical advancements.

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