Production Method 1

6890-03-5

89854-96-6

Reaction Conditions

1.1 Reagents: Potassium ferricyanide Solvents: Water

Reference

N-Demethylation with potassium ferricyanide

Perrine, Theodore D., Journal of Organic Chemistry, 1951, 16, 1303-7

Production Method 2

55998-74-8

89854-96-6

Reaction Conditions

Reference

Reduction of enaminones in the preparation of 3-aminocyclohexanols. Novel preparation of tetronic acid

Greenhill, John V.; Ramli, Mohamed; Tomassini, Therezinha, Journal of the Chemical Society, 1975, (6), 588-91

3-(Methylamino)cyclohexanol Raw materials

• 2-Cyclohexen-1-one, 3-(methylamino)-
• 3-(Dimethylamino)cyclohexanol

3-(Methylamino)cyclohexanol Preparation Products

• 3-(Methylamino)cyclohexanol (89854-96-6)

• 1. EWOD-driven droplet microfluidic device integrated with optoelectronic tweezers as an automated platform for cellular isolation and analysis?
  Gaurav J. Shah,Eric P.-Y. Chiou,Ming C. Wu,Chang-Jin “CJ” Kim Lab Chip, 2009,9, 1732-1739
• 2. Fast-pulsing NMR techniques for the detection of weak interactions: successful natural abundance probe of hydrogen bonds in peptides?
  Amandine Altmayer-Henzien,Valérie Declerck,David J. Aitken,Ewen Lescop,Denis Merlet,Jonathan Farjon Org. Biomol. Chem., 2013,11, 7611-7615
• 3. Distinct correlation between (CN2)x units and pores: a low-cost method for predesigned wide range control of micropore size of porous carbon?
  Xiaotong Feng,Lei Bian,Jie Ma,Lei Zhou,Xiayan Wang,Guangsheng Guo,Qiaosheng Pu Chem. Commun., 2019,55, 3963-3966
• 4. Estimates of hydride ion stability in condensed systems: energy of formation and solvation in aqueous and polar-organic solvents
  Craig A. Kelly,David R. Rosseinsky Phys. Chem. Chem. Phys., 2001,3, 2086-2090
• 5. Excimer emission and magnetoluminescence of radical-based zinc(ii) complexes doped in host crystals?
  Shojiro Kimura,Tetsuro Kusamoto Chem. Commun., 2020,56, 11195-11198

• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Secondary alcohols
• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Alcohols and polyols Secondary alcohols

Comprehensive Overview of 3-(Methylamino)cyclohexanol (CAS No. 89854-96-6): Properties, Applications, and Industry Insights

3-(Methylamino)cyclohexanol (CAS No. 89854-96-6) is a versatile organic compound with a cyclohexanol backbone substituted with a methylamino group. This structural feature makes it valuable in pharmaceutical intermediates, agrochemical synthesis, and specialty chemical applications. The compound's unique cyclohexanol derivative properties have garnered attention in research circles, particularly for its potential in designing novel bioactive molecules.

Recent trends in green chemistry and sustainable synthesis have increased interest in optimizing production methods for 3-(Methylamino)cyclohexanol. Researchers are exploring catalytic processes to improve yield while reducing environmental impact—a response to growing industry demands for eco-friendly chemical manufacturing. The compound's chiral center also makes it relevant to asymmetric synthesis studies, a hot topic in modern organic chemistry.

From a commercial perspective, 89854-96-6 has seen steady demand growth due to its role in producing high-value fine chemicals. Analytical data shows particular interest from pharmaceutical companies investigating cyclohexanol-based building blocks for drug development. The compound's balanced lipophilicity and hydrogen bonding capacity make it attractive for molecular design applications.

Quality specifications for 3-(Methylamino)cyclohexanol typically emphasize purity levels (>98%), with HPLC being the preferred analytical method. Storage recommendations highlight protection from moisture and oxidation—key considerations for maintaining the compound's stability during transportation and long-term storage. These technical details address common queries from quality control professionals searching for handling protocols for amino-alcohol compounds.

Emerging applications in material science have expanded the potential uses of CAS 89854-96-6. Some studies report its incorporation into polymer matrices to modify material properties, aligning with current interests in functionalized materials. This interdisciplinary potential makes the compound particularly interesting for researchers working at the chemistry-materials science interface.

Regulatory aspects of 3-(Methylamino)cyclohexanol production and handling continue to evolve with changing chemical safety standards. Proactive companies are investing in REACH compliance documentation and lifecycle assessment studies—topics frequently searched by compliance officers in the chemical industry. These measures ensure market access while addressing growing consumer concerns about responsible chemical production.

The global market for cyclohexanol derivatives shows regional variations in demand patterns. Asia-Pacific currently leads in consumption growth, reflecting broader trends in specialty chemical manufacturing relocation. Market analysts tracking 89854-96-6 price trends note increasing competition among suppliers, driving innovations in production scale-up technologies.

Technical literature reveals ongoing research into the structure-activity relationships of 3-(Methylamino)cyclohexanol analogs. Computational chemistry approaches, including molecular docking studies, are being applied to predict potential biological activities—a methodology gaining popularity among medicinal chemists. These advanced techniques address the growing demand for rational drug design approaches in the pharmaceutical industry.

From a safety perspective, standard operating procedures for amino-alcohol handling apply to this compound. Industrial users frequently search for compatibility data regarding storage containers and transfer systems, emphasizing the need for comprehensive technical documentation. Proper industrial hygiene measures remain essential when working with this chemical in bulk quantities.

Looking forward, the development of continuous flow synthesis methods for 89854-96-6 represents an active research frontier. This aligns with industry-wide movements toward process intensification and Industry 4.0 adoption in chemical manufacturing. Such innovations could significantly impact production economics and environmental footprints—key considerations for sustainable chemical development.

• 2987-05-5(4-(methylamino)cyclohexan-1-ol)
• 22348-44-3(trans-4-methylamino-cyclohexanol)
• 923023-08-9(trans-4-Methylamino-cyclohexanol hydrochloride)
• 948883-68-9(cis-4-methylamino-cyclohexanol hydrochloride (1:1))
• 343864-18-6(4-[(propan-2-yl)amino]cyclohexan-1-ol)
• 22348-38-5(cis-4-methylamino-cyclohexanol)
• 104618-16-8(Cyclohexanol, 4-(propylamino)-)
• 155723-68-5(2-Pentanol, 4-[(1-methylethyl)amino]-, (2R,4S)-rel-)
• 155723-69-6(2-Pentanol, 4-[(1-methylethyl)amino]-, (2R,4R)-rel-)
• 98007-62-6(1,2-Butanediol, 4-(cyclohexylamino)-)