Production Method 1

41037-28-9

898391-75-8

Reaction Conditions

1.1 Reagents: Selenium dioxide Solvents: 1,4-Dioxane ,  Water ;  2 h, 100 °C

Reference

Structural optimization towards promising β-methyl-4-acrylamido quinoline derivatives as PI3K/mTOR dual inhibitors for anti-cancer therapy: The in vitro and in vivo biological evaluation

He, Ruoyu; Xu, Bingyong; Ping, Li; Lv, Xiaoqing, European Journal of Medicinal Chemistry, 2021, 214,

Production Method 2

41037-28-9

898391-75-8

Reaction Conditions

1.1 Reagents: Iodine ,  Oxygen Solvents: Dimethyl sulfoxide ;  4 - 6 h, 110 °C
1.2 Solvents: Water

Reference

Metal-free oxidative C(sp3)-H functionalization: a facile route to quinoline formaldehydes from methyl-azaheteroarenes

Weng, Wei-Zhao; Guo, Jiang-Shan; Liu, Kai-Xuan; Shao, Tian-Qi; Song, Li-Qun; et al, Canadian Journal of Chemistry, 2020, 98(4), 179-183

Production Method 3

41037-28-9

898391-75-8

Reaction Conditions

1.1 Reagents: Dichloroacetic acid ,  Iodobenzene diacetate ,  Water Solvents: Dimethyl sulfoxide ;  48 h, rt
1.2 Reagents: Sodium carbonate Solvents: Water

Reference

Metal-Free Chemoselective Oxidation of 4-Methylquinolines into Quinoline-4-Carbaldehydes

Xu, Jincheng; Li, Yang; Ding, Tianling; Guo, Hao, Chemistry - An Asian Journal, 2021, 16(20), 3114-3117

Production Method 4

41037-28-9

898391-75-8

Reaction Conditions

1.1 Reagents: Selenium dioxide Solvents: 1,4-Dioxane ,  Water ;  2 h, 100 °C

Reference

Novel 4-acrylamido-quinoline derivatives as potent PI3K/mTOR dual inhibitors: the design, synthesis, and in vitro and in vivo biological evaluation

Ma, Xiaodong; Shen, Li; Zhang, Jiankang; Liu, Guoqiang; Zhan, Shuyu; et al, Frontiers in Chemistry (Lausanne, 2019, 7,

Production Method 5

14874-70-5

2300039-54-5

898391-75-8

Reaction Conditions

1.1 Reagents: Oxygen ,  Cesium fluoride Solvents: Ethyl acetate ;  15 h, 25 °C

Reference

Transition-Metal-Free Oxidation of Benzylic C-H Bonds of Six-Membered N-Heteroaromatic Compounds

Gao, Xianying; Han, Shuaijun; Zheng, Maolin; Liang, Apeng; Li, Jingya; et al, Journal of Organic Chemistry, 2019, 84(7), 4040-4049

6-Bromoquinoline-4-carbaldehyde Raw materials

• Borate(1-),tetrafluoro-
• Quinolinium, 6-bromo-1-methoxy-4-methyl-
• 6-Bromo-4-methylquinoline

6-Bromoquinoline-4-carbaldehyde Preparation Products

• 6-Bromoquinoline-4-carbaldehyde (898391-75-8)

• 1. Enabling non-flammable Li-metal batteries via electrolyte functionalization and interface engineering?
  Jing Yu,Yu-Qi Lyu,Jiapeng Liu,Mohammed B. Effat,Junxiong Wu J. Mater. Chem. A, 2019,7, 17995-18002
• 2. Fast synthesis of copper nanoclusters through the use of hydrogen peroxide additive and their application for the fluorescence detection of Hg2+ in water samples?
  Liao Xiaoqing,Li Ruiyi,Li Zaijun,Sun Xiulan,Wang Zhouping,Liu Junkang New J. Chem., 2015,39, 5240-5248
• 3. Excitable dynamics in the bromate–sulfite–ferrocyanide reaction
  J. Zagora,M. Vosla?,L. Schreiberová,I. Schreiber Phys. Chem. Chem. Phys., 2002,4, 1284-1291
• 4. Enabling chloride salts for thermal energy storage: implications of salt purity?
  J. Matthew Kurley,Phillip W. Halstenberg,Abbey McAlister,Stephen Raiman,Richard T. Mayes RSC Adv., 2019,9, 25602-25608
• 5. Evolution of calcium phosphate precipitation in hanging drop vapor diffusion by in situRaman microspectroscopy
  Gloria Belén Ramírez-Rodríguez,José Manuel Delgado-López,Jaime Gómez-Morales CrystEngComm, 2013,15, 2206-2212

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Quinolines and derivatives Haloquinolines

• 877-03-2(5-Bromo-1H-indole-3-carbaldehyde)
• 885-23-4(acridine-9-carbaldehyde)
• 1416439-88-7(1-(7-bromo-4-quinolyl)ethanone)
• 70401-29-5(9-Acridinecarboxaldehyde,2-methyl-)
• 919293-23-5(Benz[h]isoquinoline-6-carboxaldehyde, 9-bromo-)
• 160233-76-1(6-Bromoquinoline-4-carboxylic acid)
• 898391-87-2(8-Bromoquinoline-4-carbaldehyde)
• 22934-41-4(Quinoline-5-carbaldehyde)
• 41037-28-9(6-Bromo-4-methylquinoline)
• 4363-93-3(Quinoline-4-carbaldehyde)