Cas no 89810-44-6 (2-formamido-3-methylpentanoic acid)

2-Formamido-3-methylpentanoic acid is a chiral non-proteinogenic amino acid derivative with potential applications in organic synthesis and pharmaceutical research. Its structure, featuring both formamido and methyl substituents on a pentanoic acid backbone, makes it a versatile intermediate for the preparation of peptidomimetics and bioactive compounds. The compound's stereochemistry and functional groups allow for selective modifications, enabling its use in asymmetric synthesis and medicinal chemistry. Its stability under standard conditions and compatibility with common coupling reagents further enhance its utility in peptide and small-molecule derivatization. This compound is particularly valuable for researchers exploring structure-activity relationships or designing novel therapeutic agents.
2-formamido-3-methylpentanoic acid structure
89810-44-6 structure
Product Name:2-formamido-3-methylpentanoic acid
CAS No:89810-44-6
MF:C7H13NO3
MW:159.183022260666
CID:993869
PubChem ID:433629
Update Time:2025-05-25

2-formamido-3-methylpentanoic acid Chemical and Physical Properties

Names and Identifiers

    • 2-formamido-3-methylpentanoic acid
    • NSC334341
    • 89810-44-6
    • DTXSID70330922
    • NSC-334341
    • SCHEMBL2377589
    • 2-formamido-3-methyl-pentanoic acid
    • EN300-1297432
    • DS-004077
    • Inchi: 1S/C7H13NO3/c1-3-5(2)6(7(10)11)8-4-9/h4-6H,3H2,1-2H3,(H,8,9)(H,10,11)
    • InChI Key: IONXXIKCTQHZNC-UHFFFAOYSA-N
    • SMILES: OC(C(C(C)CC)NC=O)=O

Computed Properties

  • Exact Mass: 159.09
  • Monoisotopic Mass: 159.09
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 4
  • Complexity: 147
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 2
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 0.9
  • Topological Polar Surface Area: 66.4?2

Experimental Properties

  • Density: 1.093
  • Boiling Point: 360.6°C at 760 mmHg
  • Flash Point: 171.9°C
  • Refractive Index: 1.458

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Additional information on 2-formamido-3-methylpentanoic acid

Compound CAS No 89810-44-6: A Comprehensive Overview of 2-formamido-3-methylpentanoic Acid

2-formamido-3-methylpentanoic acid, identified by the CAS registry number 89810-44-6, is a compound of significant interest in the fields of organic chemistry and biochemistry. This compound, with its unique structure and properties, has garnered attention due to its potential applications in various scientific domains. In this article, we delve into the structural characteristics, chemical properties, biological implications, and recent advancements associated with 2-formamido-3-methylpentanoic acid.

The molecular structure of 2-formamido-3-methylpentanoic acid is defined by its pentanoic acid backbone, with a formamido group attached at the second carbon and a methyl group at the third carbon. This configuration imparts distinct chemical properties, making it a versatile molecule for synthetic and analytical purposes. The compound's structure allows for a range of functional group interactions, which are pivotal in its utilization across different research areas.

Recent studies have highlighted the role of 2-formamido-3-methylpentanoic acid in peptide synthesis and drug discovery. Its formamido group facilitates the formation of amide bonds, a critical step in constructing peptides and proteins. Researchers have explored its potential as a building block in medicinal chemistry, where it serves as a precursor for developing bioactive compounds with therapeutic applications.

In terms of chemical synthesis, 2-formamido-3-methylpentanoic acid is often synthesized via multi-step processes involving nucleophilic acyl substitution or amidation reactions. These methods ensure high purity and yield, which are essential for downstream applications in pharmaceuticals and biotechnology.

The biological implications of 2-formamido-3-methylpentanoic acid are equally intriguing. Studies have shown that this compound exhibits moderate activity against certain enzymes, making it a candidate for further exploration in enzyme inhibition assays. Additionally, its structural similarity to naturally occurring amino acids suggests potential roles in metabolic studies and nutraceutical development.

From an environmental perspective, understanding the degradation pathways of 2-formamido-3-methylpentanoic acid is crucial for assessing its ecological impact. Recent research has focused on microbial degradation mechanisms, revealing that certain bacterial strains can metabolize this compound under specific conditions.

In conclusion, 2-formamido-3-methylpentanoic acid (CAS No 89810-44-6) stands as a multifaceted compound with diverse applications across chemistry and biology. Its structural versatility and functional group reactivity continue to drive innovative research, positioning it as a valuable tool in modern scientific endeavors.

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