- Improvement in the synthesis of 2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(Z)-methoxyiminoacetic acid 2-benzothiazolyl thioesterGao, Shihao; Gao, Changquan; Sun, Chenghui; Zhao, Xinqi, Frontiers of Chemical Engineering in China, 2008, 2(1), 80-84
Cas no 89604-91-1 ((Z)-S-Benzodthiazol-2-yl 2-(5-amino-1,2,4-thia-diazol-3-yl)-2-(methoxyimino)ethanethioate)
89604-91-1 structure
Product Name:(Z)-S-Benzodthiazol-2-yl 2-(5-amino-1,2,4-thia-diazol-3-yl)-2-(methoxyimino)ethanethioate
CAS No:89604-91-1
MF:C12H9N5O2S3
MW:351.42715716362
MDL:MFCD08460128
CID:61291
PubChem ID:13826586
Update Time:2024-10-26
(Z)-S-Benzodthiazol-2-yl 2-(5-amino-1,2,4-thia-diazol-3-yl)-2-(methoxyimino)ethanethioate Chemical and Physical Properties
Names and Identifiers
-
- S-2-Benzothiazolyl ( Z ) -2-(5-amino-1,2,4-thiadiazol-3-yl)-2-methoxyimino thioacetate
- ZAEM
- (S)-2-Benzothiazolyl (Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-methoxyiminothioacetate
- (Z)-S-Benzo[d]thiazol-2-yl 2-(5-amino-1,2,4-thia-diazol-3-yl)-2-(methoxyimino)ethanethioate
- S-2-BENZOTHIAZOLYL(Z)-2-(5-AMINO-1,2,4-THIADIAZOL-3-YL)-2-METHOXYIMINO THIOACETATE (ZAEM)
- (Z)-S-benzo[d]thiazol-2-yl 2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(methoxyimino)ethanethioate
- 2-Mercaptobenzothiazoyl(Z)-2-(2-amino-1,2,4-thiadiazol-4-yl)-2-methoxyiminothioacetate
- ATDM
- DAMA
- Diethyl thiophosphoryl (Z)-(2-amino-1,3-thiazol-4-yl)(methoxyimino)acetate
- O,O-DIETHYLTHIOPHOSPHORYL (Z)-2-(2-AMINOTHIAZOL-4-YL)-2-METHOXYIMINOACETATE
- S-(2-benzothiazolyl) (Z)-2-(2-amino-1,2,4-thiadiazol-3-yl)-2-(methoxyimino)thioacetate
- ZAEM:S-2-
- ZeaM
- 1,2,4-Thiadiazole-3-ethanethioicacid, 5-amino-a-(methoxyimino)-,S-2-benzothiazolyl ester, (Z)-
- 1,2,4-Thiadiazole-3-ethanethioic acid, 5-amino-α-(methoxyimino)-, S-2-benzothiazolyl ester, (Z)- (ZCI)
- S-2-Benzothiazolyl (αZ)-5-amino-α-(methoxyimino)-1,2,4-thiadiazole-3-ethanethioate (ACI)
- AKOS015963307
- S-Benzothiazol-2-yl (Z)-(5-amino-1,2,4-thiadiazol-3-yl)- methoxyiminothioacetate
- SCHEMBL2453598
- EC 453-580-6
- S-(1,3-benzothiazol-2-yl) (2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-methoxyiminoethanethioate
- J-502667
- 4-Thiazoleethanethioicacid,a-[(acetyloxy)imino]-2-amino-,s-2-benzothiazolyl ester,(az)-
- AC-104
- 89604-91-1
- (Z)-S-Benzodthiazol-2-yl 2-(5-amino-1,2,4-thia-diazol-3-yl)-2-(methoxyimino)ethanethioate
-
- MDL： MFCD08460128
- Inchi： 1S/C12H9N5O2S3/c1-19-16-8(9-15-11(13)22-17-9)10(18)21-12-14-6-4-2-3-5-7(6)20-12/h2-5H,1H3,(H2,13,15,17)/b16-8-
- InChI Key： XJESSAAEFWMELV-PXNMLYILSA-N
- SMILES： S(C1SC2C=CC=CC=2N=1)C(=O)/C(/C1N=C(N)SN=1)=N\OC
Computed Properties
- Exact Mass: 350.99200
- Monoisotopic Mass: 350.99183807g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 5
- Heavy Atom Count: 22
- Rotatable Bond Count: 5
- Complexity: 453
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 1
- Undefined Bond Stereocenter Count: 0
- XLogP3: 3.9
- Topological Polar Surface Area: 185?2
Experimental Properties
- Density: 1.73
- Boiling Point: 565.2 oC at 760 mmHg
- Flash Point: 565.2 oC at 760 mmHg
- Refractive Index: 1.842
- PSA: 184.08000
- LogP: 3.06810
(Z)-S-Benzodthiazol-2-yl 2-(5-amino-1,2,4-thia-diazol-3-yl)-2-(methoxyimino)ethanethioate Security Information
-
Hazardous Material Identification：
(Z)-S-Benzodthiazol-2-yl 2-(5-amino-1,2,4-thia-diazol-3-yl)-2-(methoxyimino)ethanethioate Customs Data
- HS CODE：2934999090
- Customs Data：
China Customs Code:
2934999090Overview:
2934999090. Other heterocyclic compounds. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%
Declaration elements:
Product Name, component content, use to
Summary:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
(Z)-S-Benzodthiazol-2-yl 2-(5-amino-1,2,4-thia-diazol-3-yl)-2-(methoxyimino)ethanethioate Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | Z078460-5g |
(Z)-S-Benzo[d]thiazol-2-yl 2-(5-amino-1,2,4-thia-diazol-3-yl)-2-(methoxyimino)ethanethioate |
89604-91-1 | 5g |
$ 95.00 | 2022-06-02 | ||
| TRC | Z078460-10g |
(Z)-S-Benzo[d]thiazol-2-yl 2-(5-amino-1,2,4-thia-diazol-3-yl)-2-(methoxyimino)ethanethioate |
89604-91-1 | 10g |
$ 155.00 | 2022-06-02 | ||
| TRC | Z078460-25g |
(Z)-S-Benzo[d]thiazol-2-yl 2-(5-amino-1,2,4-thia-diazol-3-yl)-2-(methoxyimino)ethanethioate |
89604-91-1 | 25g |
$ 310.00 | 2022-06-02 | ||
| eNovation Chemicals LLC | D630747-500g |
(S)-2-Benzothiazolyl (Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-methoxyiminothioacetate |
89604-91-1 | 97% | 500g |
$500 | 2024-06-05 | |
| eNovation Chemicals LLC | D630747-1kg |
(S)-2-Benzothiazolyl (Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-methoxyiminothioacetate |
89604-91-1 | 97% | 1kg |
$980 | 2024-06-05 | |
| eNovation Chemicals LLC | D381158-1kg |
(S)-2-Benzothiazolyl (Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-methoxyiminothioacetate |
89604-91-1 | 97% | 1kg |
$775 | 2024-05-24 | |
| SHANG HAI HAO HONG Biomedical Technology Co., Ltd. | 1531790-250g |
S-(benzo[d]thiazol-2-yl) (Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(methoxyimino)ethanethioate |
89604-91-1 | 98% | 250g |
￥1560.00 | 2024-04-26 | |
| A2B Chem LLC | AH81967-500mg |
(S)-2-Benzothiazolyl (Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-methoxyiminothioacetate |
89604-91-1 | 500mg |
$198.00 | 2024-04-19 | ||
| A2B Chem LLC | AH81967-1g |
(S)-2-Benzothiazolyl (Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-methoxyiminothioacetate |
89604-91-1 | 1g |
$315.00 | 2024-04-19 | ||
| A2B Chem LLC | AH81967-5g |
(S)-2-Benzothiazolyl (Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-methoxyiminothioacetate |
89604-91-1 | 5g |
$1092.00 | 2024-04-19 |
(Z)-S-Benzodthiazol-2-yl 2-(5-amino-1,2,4-thia-diazol-3-yl)-2-(methoxyimino)ethanethioate Production Method
Production Method 1
Reaction Conditions
1.1 Reagents: Triphenylphosphine Solvents: 1,2-Dichloroethane ; 30 min, 20 °C
1.2 Catalysts: Triethylamine ; 10 min, 20 °C; 4 h, 20 °C
1.2 Catalysts: Triethylamine ; 10 min, 20 °C; 4 h, 20 °C
Reference
Production Method 2
Reaction Conditions
1.1 Reagents: Piperidine ; rt → 106 °C; 30 min, 106 °C
1.2 Reagents: Triethylamine ; 10 min, 106 °C; 5 h, reflux; reflux → 0 °C
1.2 Reagents: Triethylamine ; 10 min, 106 °C; 5 h, reflux; reflux → 0 °C
Reference
- Synthesis of 2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(Z)-methoxyimino acetic acid S-benzothiazolyl thioesterGao, Shihao; Gao, Changquan; Zhao, Xinqi, Zhongguo Yiyao Gongye Zazhi, 2008, 39(9), 645-646
Production Method 3
Reaction Conditions
1.1 Reagents: Triethylamine , Triethyl phosphite Solvents: Dichloromethane ; 4 h, 25 °C
Reference
- Improvement in the synthesis of 2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(z)methoxyiminoacetic acid 2-benzothiazolyl thioesterCheng, Yan; Zheng, Gengxiu; Shi, Gang, Jinan Daxue Xuebao, 2011, 25(2), 171-174
Production Method 4
Reaction Conditions
1.1 Reagents: Triphenylphosphine Solvents: Dichloromethane ; 5 h, 30 °C
Reference
- Method for preparation of Cefozopran hydrochloride and its powder injection, China, , ,
(Z)-S-Benzodthiazol-2-yl 2-(5-amino-1,2,4-thia-diazol-3-yl)-2-(methoxyimino)ethanethioate Raw materials
- 2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-(methoxyimino)acetic Acid
- 2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-(methoxyimino)acetamide
- 1,3-benzothiazole-2-thiol
- 2-(1,3-benzothiazol-2-yldisulfanyl)-1,3-benzothiazole
- (2Z)-2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-methoxyiminoacetic acid
(Z)-S-Benzodthiazol-2-yl 2-(5-amino-1,2,4-thia-diazol-3-yl)-2-(methoxyimino)ethanethioate Preparation Products
(Z)-S-Benzodthiazol-2-yl 2-(5-amino-1,2,4-thia-diazol-3-yl)-2-(methoxyimino)ethanethioate Related Literature
-
Hamid Heydari,Mohammad B. Gholivand New J. Chem., 2017,41, 237-244
-
Juan J. Sánchez,Miguel López-Haro,Juan C. Hernández-Garrido,Ginesa Blanco,Miguel A. Cauqui,José M. Rodríguez-Izquierdo,José A. Pérez-Omil,José J. Calvino,María P. Yeste J. Mater. Chem. A, 2019,7, 8993-9003
-
Luke L. Lairson,Warren W. Wakarchuk Chem. Commun., 2007, 365-367
-
Xixi Li,Nanwei Zhu,Ruohan Li,Qinpu Zhang Anal. Methods, 2020,12, 3376-3381
-
Teresita Carrillo-Hernández,Philippe Schaeffer,Pierre Albrecht Chem. Commun., 2001, 1976-1977
89604-91-1 ((Z)-S-Benzodthiazol-2-yl 2-(5-amino-1,2,4-thia-diazol-3-yl)-2-(methoxyimino)ethanethioate) Related Products
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- 104797-47-9(S-2-Benzothiazolyl (Z)-2-(2-Aminothiazol-4-yl)-2-acetyloxyiminothioacetate)
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