- Discovery of 5-HT6 receptor ligands based on virtual HTSTasler, Stefan; Kraus, Juergen; Wuzik, Andreas; Mueller, Oliver; Aschenbrenner, Andrea; et al, Bioorganic & Medicinal Chemistry Letters, 2007, 17(22), 6224-6229
Cas no 89465-97-4 (4-bromo-2-chloro-1-nitro-benzene)
4-Bromo-2-chloro-1-nitro-benzene (CAS: 7295-06-3) is a halogenated nitroaromatic compound widely used as an intermediate in organic synthesis. Its distinct substitution pattern—bromo, chloro, and nitro groups on the benzene ring—makes it a versatile building block for pharmaceuticals, agrochemicals, and specialty chemicals. The electron-withdrawing nitro group enhances reactivity in nucleophilic aromatic substitution (SNAr) reactions, while the halogen substituents allow further functionalization via cross-coupling or metal-catalyzed transformations. This compound exhibits high purity and stability, ensuring consistent performance in multi-step synthetic routes. Its well-defined structure and predictable reactivity make it valuable for constructing complex aromatic frameworks in research and industrial applications.
89465-97-4 structure
Product Name:4-bromo-2-chloro-1-nitro-benzene
CAS No:89465-97-4
MF:C6H3BrClNO2
MW:236.450519800186
MDL:MFCD11848538
CID:1007075
PubChem ID:22280606
Update Time:2025-10-29
4-bromo-2-chloro-1-nitro-benzene Chemical and Physical Properties
Names and Identifiers
-
- 4-bromo-2-chloro-1-nitrobenzene
- AKOS000279379
- Benzene, 4-bromo-2-chloro-1-nitro-
- CS-16100
- FT-0707740
- Y12426
- QWRNVDWDFCINEY-UHFFFAOYSA-N
- MFCD11848538
- SY021887
- 89465-97-4
- SCHEMBL2485012
- 4-Nitro-3-chlorophenyl bromide
- 4-Bromo-2-chloronitrobenzene
- CS-0088444
- 4-Bromo-2-chloro-1-nitrobenzene (ACI)
- 4-bromo-2-chloro-1-nitro-benzene
- DB-316303
-
- MDL： MFCD11848538
- Inchi： 1S/C6H3BrClNO2/c7-4-1-2-6(9(10)11)5(8)3-4/h1-3H
- InChI Key： QWRNVDWDFCINEY-UHFFFAOYSA-N
- SMILES： [O-][N+](C1C(Cl)=CC(Br)=CC=1)=O
Computed Properties
- Exact Mass: 234.904
- Monoisotopic Mass: 234.904
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 0
- Heavy Atom Count: 11
- Rotatable Bond Count: 1
- Complexity: 161
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 3.2
- Topological Polar Surface Area: 45.8A^2
Experimental Properties
- Boiling Point: 286.1±20.0℃/760mmHg
4-bromo-2-chloro-1-nitro-benzene Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Alichem | A013027139-250mg |
4-Bromo-2-chloronitrobenzene |
89465-97-4 | 97% | 250mg |
$494.40 | 2023-08-31 | |
| Alichem | A013027139-500mg |
4-Bromo-2-chloronitrobenzene |
89465-97-4 | 97% | 500mg |
$831.30 | 2023-08-31 | |
| Alichem | A013027139-1g |
4-Bromo-2-chloronitrobenzene |
89465-97-4 | 97% | 1g |
$1475.10 | 2023-08-31 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-JM259-50mg |
4-bromo-2-chloro-1-nitro-benzene |
89465-97-4 | 95+% | 50mg |
76.0CNY | 2021-07-17 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-JM259-200mg |
4-bromo-2-chloro-1-nitro-benzene |
89465-97-4 | 95+% | 200mg |
147.0CNY | 2021-07-17 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-JM259-1g |
4-bromo-2-chloro-1-nitro-benzene |
89465-97-4 | 95+% | 1g |
668.0CNY | 2021-07-17 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-JM259-100mg |
4-bromo-2-chloro-1-nitro-benzene |
89465-97-4 | 95+% | 100mg |
170CNY | 2021-05-07 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-JM259-250mg |
4-bromo-2-chloro-1-nitro-benzene |
89465-97-4 | 95+% | 250mg |
396CNY | 2021-05-07 | |
| Ambeed | A789979-100mg |
4-Bromo-2-chloro-1-nitrobenzene |
89465-97-4 | 95% | 100mg |
$15.0 | 2025-04-15 | |
| Ambeed | A789979-250mg |
4-Bromo-2-chloro-1-nitrobenzene |
89465-97-4 | 95% | 250mg |
$18.0 | 2025-04-15 |
4-bromo-2-chloro-1-nitro-benzene Production Method
Production Method 1
Reaction Conditions
1.1 Reagents: Acetic acid , Sodium peroxoborate ; 3 h, 60 °C
Reference
Production Method 2
Reaction Conditions
Reference
- Applicability aspects of transition metal-catalyzed aromatic amination protocols in medicinal chemistryTasler, Stefan; Mies, Jan; Lang, Martin, Advanced Synthesis & Catalysis, 2007, 349, 2286-2300
4-bromo-2-chloro-1-nitro-benzene Raw materials
4-bromo-2-chloro-1-nitro-benzene Preparation Products
4-bromo-2-chloro-1-nitro-benzene Related Literature
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Eunhak Lim,Jiyoung Heo,Seong Keun Kim Nanoscale, 2019,11, 11369-11378
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