Production Method 1

885518-46-7

885518-50-3

Reaction Conditions

1.1 Reagents: Iron ,  Ammonium chloride Solvents: Ethanol ,  Water ;  1 h, 80 °C

Reference

4,6-Substituted-1H-indazoles as potent IDO1/TDO dual inhibitors

Yang, Lingling; Chen, Yang; He, Junlin; Njoya, Emmanuel Mfotie; Chen, Jianjun; et al, Bioorganic & Medicinal Chemistry, 2019, 27(6), 1087-1098

Production Method 2

885518-46-7

885518-50-3

Reaction Conditions

1.1 Reagents: Ammonium chloride Solvents: Ethanol ,  Water ;  5 min, rt
1.2 Reagents: Iron ;  rt; 25 min, 80 °C

Reference

Discovery and preliminary structure-activity relationship of 1H-indazoles with promising indoleamine-2,3-dioxygenase 1 (IDO1) inhibition properties

Qian, Shan; He, Tao; Wang, Wei; He, Yanying; Zhang, Man; et al, Bioorganic & Medicinal Chemistry, 2016, 24(23), 6194-6205

6-Bromo-1H-indazol-4-amine Raw materials

• 6-Bromo-4-nitro-1H-indazole

6-Bromo-1H-indazol-4-amine Preparation Products

• 6-Bromo-1H-indazol-4-amine (885518-50-3)

• 1. Evolution in surface coverage of CH3NH3PbI3?XClXvia heat assisted solvent vapour treatment and their effects on photovoltaic performance of devices
  Dhirendra K. Chaudhary,Pramendra Kumar,Lokendra Kumar RSC Adv., 2016,6, 94731-94738
• 2. Dissociation of large gaseous serine clusters produces abundant protonated serine octamer
  Jacob S. Jordan,Evan R. Williams Analyst, 2021,146, 2617-2625
• 3. Enantio- & chemo-selective preparation of enantiomerically enriched aliphatic nitro alcohols using Candida parapsilosis ATCC 7330
  Sowmyalakshmi Venkataraman RSC Adv., 2015,5, 73807-73813
• 4. Emulsion soft templating of carbide-derived carbon nanospheres with controllable porosity for capacitive electrochemical energy storage?
  M. Zeiger,N. J?ckel,P. Strubel,L. Borchardt,R. Reinhold,W. Nickel,J. Eckert,V. Presser,S. Kaskel J. Mater. Chem. A, 2015,3, 17983-17990
• 5. Estimates of hydride ion stability in condensed systems: energy of formation and solvation in aqueous and polar-organic solvents
  Craig A. Kelly,David R. Rosseinsky Phys. Chem. Chem. Phys., 2001,3, 2086-2090

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Benzopyrazoles Indazoles

• 1000342-40-4(6-Amino-3,4-dibromo (1H)Indazole)
• 1198438-39-9(6-bromo-1-methyl-1h-indazol-4-amine)
• 61272-71-7(5-Bromo-1H-indazol-3-amine)
• 914311-50-5(4-Bromo-1H-indazol-3-amine)
• 404827-77-6(6-Bromo-1H-indazol-3-amine)
• 953411-10-4(7-Bromo-1H-indazol-5-amine)
• 796970-45-1(4,6-Dibromo-1H-indazol-3-amine)
• 885521-25-5(3-Bromo-1H-indazol-4-amine)
• 885518-53-6(4-Bromo-1H-indazol-6-amine)
• 1360900-38-4(5-Bromo-1H-indazol-6-amine)