Cas no 885279-83-4 (4-(4-(hydroxymethyl)thiazol-2-yl)phenol)

4-(4-(Hydroxymethyl)thiazol-2-yl)phenol is a heterocyclic compound featuring both a thiazole and phenol moiety, with a hydroxymethyl functional group enhancing its reactivity. This structure imparts versatility in synthetic applications, particularly in pharmaceutical and material science research. The phenol group offers potential for further derivatization, while the thiazole ring contributes to its stability and binding affinity in coordination chemistry. The hydroxymethyl substituent facilitates cross-linking or conjugation, making it valuable for polymer synthesis or bioconjugation. Its balanced polarity ensures moderate solubility in organic solvents, aiding purification and handling. This compound is a promising intermediate for developing bioactive molecules or functional materials.
4-(4-(hydroxymethyl)thiazol-2-yl)phenol structure
885279-83-4 structure
Product Name:4-(4-(hydroxymethyl)thiazol-2-yl)phenol
CAS No:885279-83-4
MF:C10H9NO2S
MW:207.248961210251
MDL:MFCD06738405
CID:892797
PubChem ID:135741993
Update Time:2025-06-11

4-(4-(hydroxymethyl)thiazol-2-yl)phenol Chemical and Physical Properties

Names and Identifiers

    • 4-(4-HYDROXYMETHYL-THIAZOL-2-YL)-PHENOL
    • 4-(4-HYDROXYMETHYL-THIAZOL-2-YL)PHENOL,
    • 4-[4-(hydroxymethyl)-3H-1,3-thiazol-2-ylidene]cyclohexa-2,5-dien-1-one
    • 4-(4-(Hydroxymethyl)thiazol-2-yl)phenol
    • 4-[4-(HYDROXYMETHYL)-1,3-THIAZOL-2-YL]PHENOL
    • FT-0743458
    • CS-0330636
    • 885279-83-4
    • AB27104
    • 4-[4-(Hydroxymethyl)-1,3-thiazol-2(3H)-ylidene]cyclohexa-2,5-dien-1-one
    • DTXSID60696069
    • MFCD06738405
    • A861891
    • 4-(4-(hydroxymethyl)thiazol-2-yl)-phenol
    • DB-077820
    • 4-(4-(hydroxymethyl)thiazol-2-yl)phenol
    • MDL: MFCD06738405
    • Inchi: 1S/C10H9NO2S/c12-5-8-6-14-10(11-8)7-1-3-9(13)4-2-7/h1-4,6,12-13H,5H2
    • InChI Key: VZCPHRCBMAEIKY-UHFFFAOYSA-N
    • SMILES: S1C=C(CO)N=C1C1C=CC(=CC=1)O

Computed Properties

  • Exact Mass: 207.03500
  • Monoisotopic Mass: 207.03539970g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 14
  • Rotatable Bond Count: 2
  • Complexity: 183
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1.4
  • Topological Polar Surface Area: 81.6?2

Experimental Properties

  • PSA: 81.59000
  • LogP: 2.00800

4-(4-(hydroxymethyl)thiazol-2-yl)phenol Customs Data

  • HS CODE:2934100090
  • Customs Data:

    China Customs Code:

    2934100090

    Overview:

    2934100090. Compounds that structurally contain a non fused thiazole ring(Whether hydrogenated or not). VAT:17.0%. Tax refund rate:9.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

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Additional information on 4-(4-(hydroxymethyl)thiazol-2-yl)phenol

Research Briefing on 4-(4-(hydroxymethyl)thiazol-2-yl)phenol (CAS: 885279-83-4) and Its Applications in Chemical Biology and Pharmaceutical Research

The compound 4-(4-(hydroxymethyl)thiazol-2-yl)phenol (CAS: 885279-83-4) has recently garnered significant attention in the fields of chemical biology and pharmaceutical research due to its unique structural properties and potential therapeutic applications. This research briefing aims to provide a comprehensive overview of the latest findings related to this compound, including its synthesis, biological activity, and potential applications in drug development. The information presented herein is based on a thorough review of recent peer-reviewed publications, patent filings, and industry reports.

Recent studies have highlighted the role of 4-(4-(hydroxymethyl)thiazol-2-yl)phenol as a versatile scaffold in medicinal chemistry. Its thiazole and phenol moieties make it an attractive candidate for the development of novel bioactive molecules. Researchers have explored its potential as a building block for the synthesis of kinase inhibitors, antimicrobial agents, and anti-inflammatory compounds. The compound's ability to interact with various biological targets has been demonstrated through in vitro and in silico studies, suggesting its broad applicability in drug discovery.

One of the key advancements in the study of 4-(4-(hydroxymethyl)thiazol-2-yl)phenol is its application in the development of small-molecule inhibitors targeting specific enzymes involved in disease pathways. For instance, recent work has shown that derivatives of this compound exhibit potent inhibitory activity against certain kinases implicated in cancer progression. These findings have spurred further research into optimizing the compound's pharmacokinetic properties to enhance its therapeutic potential. Additionally, the compound's structural features have been leveraged to design probes for studying biological processes at the molecular level.

The synthesis and characterization of 4-(4-(hydroxymethyl)thiazol-2-yl)phenol have also been the focus of recent investigations. Advances in synthetic methodologies have enabled the efficient production of this compound and its derivatives, facilitating further exploration of its biological activities. Spectroscopic techniques, including NMR and mass spectrometry, have been employed to confirm the structure and purity of synthesized compounds, ensuring the reliability of subsequent biological assays. These efforts have laid the groundwork for the development of new chemical entities based on this scaffold.

In conclusion, 4-(4-(hydroxymethyl)thiazol-2-yl)phenol (CAS: 885279-83-4) represents a promising candidate for further research in chemical biology and pharmaceutical development. Its unique structural features, combined with its demonstrated biological activities, make it a valuable tool for drug discovery and mechanistic studies. Future research should focus on optimizing its derivatives for improved efficacy and safety, as well as exploring its potential in other therapeutic areas. This briefing underscores the importance of continued investment in the study of this compound to unlock its full potential in addressing unmet medical needs.

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