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Comprehensive Overview of 2-(4-chlorophenyl)-1,3-thiazol-4-ylmethanol (CAS No. 36093-99-9): Properties, Applications, and Industry Insights

2-(4-chlorophenyl)-1,3-thiazol-4-ylmethanol (CAS No. 36093-99-9) is a specialized organic compound featuring a thiazole core substituted with a 4-chlorophenyl group and a hydroxymethyl functional group. This structurally unique molecule has garnered significant attention in pharmaceutical and agrochemical research due to its potential as a building block for bioactive molecules. The presence of both heterocyclic and aromatic moieties contributes to its versatile reactivity, making it valuable for synthesizing derivatives with tailored properties.

Recent studies highlight the growing demand for thiazole-containing compounds in drug discovery, particularly for their antimicrobial and anti-inflammatory properties. Researchers are actively exploring CAS 36093-99-9 as a precursor for developing novel small-molecule inhibitors, aligning with current trends in targeted therapy and precision medicine. Its molecular structure allows for strategic modifications, enabling the creation of compounds with enhanced bioavailability and selectivity—key factors addressed in modern medicinal chemistry discussions.

From an industrial perspective, 2-(4-chlorophenyl)-1,3-thiazol-4-ylmethanol is synthesized through optimized multi-step organic reactions, often involving cyclization and functional group interconversion techniques. Manufacturers emphasize high-purity grades (>98%) to meet the stringent requirements of pharmaceutical intermediates. Analytical methods such as HPLC and NMR spectroscopy are routinely employed for quality control, reflecting industry standards for compound characterization.

Environmental and regulatory considerations surrounding chlorinated aromatic compounds have spurred innovations in green chemistry approaches for producing CAS 36093-99-9. Sustainable solvents and catalytic methods are being adopted to minimize waste, addressing frequent queries about eco-friendly synthesis in peer-reviewed literature. This aligns with broader market shifts toward sustainable chemical production, a topic dominating ACS Green Chemistry Institute forums.

The compound’s stability profile and structure-activity relationships (SAR) are frequently discussed in patent filings, particularly for applications in crop protection formulations. Its thiazole moiety demonstrates notable interactions with biological targets, explaining its inclusion in studies about pest resistance management—a critical concern in contemporary agrochemical research.

Emerging applications of 2-(4-chlorophenyl)-1,3-thiazol-4-ylmethanol extend to material science, where its derivatives are investigated for organic electronic materials. The compound’s conjugated system shows promise for developing light-emitting diodes (LEDs) and photovoltaic devices, connecting to trending searches about energy-efficient technologies. Such interdisciplinary relevance underscores its importance beyond traditional chemistry sectors.

For researchers sourcing CAS 36093-99-9, technical specifications often include storage recommendations (e.g., ambient temperature, desiccated conditions) and handling protocols to preserve its chemical integrity. Suppliers increasingly provide custom synthesis services and bulk quantities, responding to demand fluctuations in contract research organizations (CROs).

• 23780-13-4((2-phenylthiazol-4-yl)methanol)
• 121202-20-8((2-(3-Chlorophenyl)thiazol-4-yl)methanol)
• 1178420-52-4(2-(3,5-Dichlorophenyl)thiazole-4-carboxylic acid)
• 1094355-53-9(2-(2,4-Dichlorophenyl)thiazole-4-carboxylic acid)
• 17228-98-7(2-(4-Chlorophenyl)-1,3-thiazole-4-carboxylic acid)
• 21278-77-3(2-(4-Chlorophenyl)thiazole-4-carbaldehyde)
• 639517-86-5((2-(2-Chlorophenyl)thiazol-4-yl)methanol)
• 36093-97-7((2-(p-Tolyl)thiazol-4-yl)methanol)
• 257876-07-6(2-(2,3-Dichloro-phenyl)-thiazole-4-carboxylic Acid)
• 145293-21-6(2-(4-Amino-phenyl)-thiazol-4-yl-methanol)