Production Method 1

463-52-5

879643-71-7

Reaction Conditions

1.1 Reagents: Hydrogen iodide ;  2 h, 0 °C

Reference

Fabrication of Efficient Formamidinium Tin Iodide Perovskite Solar Cells through SnF2-Pyrazine Complex

Lee, Seon Joo; et al, Journal of the American Chemical Society, 2016, 138(12), 3974-3977

Production Method 2

463-52-5

879643-71-7

Reaction Conditions

1.1 Reagents: Hydrogen iodide Solvents: Ethanol ,  Water ;  2 h, rt

Reference

Carrier-Activated Polarization in Organometal Halide Perovskites

Li, Linkai; et al, Journal of Physical Chemistry C, 2016, 120(5), 2536-2541

Production Method 3

879643-71-7

Reaction Conditions

1.1 Reagents: Hydrogen iodide

Reference

Passivating defects via 4-cyanobenzenaminium iodide enables 22.44% efficiency perovskite solar cells

Liang, Lusheng; et al, Electrochimica Acta, 2022, 413,

Formamidine Hydroiodide Raw materials

• methanimidamide

Formamidine Hydroiodide Preparation Products

• Formamidine Hydroiodide (879643-71-7)

• 1. An atomic scale study of defects in Co2FeAl
  Ravi Kumar Yadav,R. Govindaraj Phys. Chem. Chem. Phys., 2020,22, 26876-26886
• 2. An approach to C–N activation: coupling of arenesulfonyl hydrazides and arenesulfonyl chlorides with tert-amines via a metal-, oxidant- and halogen-free anodic oxidation??
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• 3. An atomistic mechanism for the degradation of perovskite solar cells by trapped charge?
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• 4. An inter-tangled network of redox-active and conducting polymers as a cathode for ultrafast rechargeable batteries
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• 5. An integrated microfluidic 3D tumor system for parallel and high-throughput chemotherapy evaluation?
  Dan Liu,Rui Hu,Zhongchao Huang,Meilin Sun,Kai Han Analyst, 2020,145, 6447-6455

• Solvents and Organic Chemicals Organic Compounds Organic nitrogen compounds Organonitrogen compounds Amidines Carboxamidines
• Material Chemicals Electrical Materials Biosensor Materials
• Catalysts and Inorganic Chemicals Inorganic Compounds Salt
• Material Chemicals Electrical Materials

Formamidine Hydroiodide (CAS No. 879643-71-7): A Comprehensive Overview

Formamidine Hydroiodide, chemically known as Formamidine Hydroiodide, is a compound with the CAS number 879643-71-7. This compound has garnered significant attention in the field of pharmaceutical and biochemical research due to its unique structural and functional properties. Formamidine Hydroiodide is an iodinated derivative of formamide, and its applications span across various domains, including medicinal chemistry, bioorganic synthesis, and the development of novel therapeutic agents.

The molecular structure of Formamidine Hydroiodide features a central formamide moiety substituted with an iodine atom at the nitrogen position. This structural feature imparts distinct reactivity and binding capabilities, making it a valuable intermediate in synthetic chemistry. The compound's ability to participate in nucleophilic substitution reactions and its role as a ligand in coordination chemistry have been extensively studied. Recent advancements in the synthesis of complex organic molecules have highlighted the utility of Formamidine Hydroiodide as a versatile building block.

In the realm of pharmaceutical research, Formamidine Hydroiodide has been explored for its potential applications in drug discovery. Its iodine substituent enhances its interaction with biological targets, making it a promising candidate for developing new pharmacophores. Studies have demonstrated its efficacy in modulating enzyme activity and binding to specific protein receptors. The compound's ability to act as a prodrug or a precursor for more complex molecules has opened new avenues in medicinal chemistry.

One of the most intriguing aspects of Formamidine Hydroiodide is its role in bioorganic synthesis. Researchers have leveraged its reactivity to construct intricate molecular frameworks, including heterocyclic compounds that exhibit significant biological activity. The use of Formamidine Hydroiodide as a starting material has led to the discovery of novel compounds with potential therapeutic benefits. For instance, derivatives of this compound have shown promise in inhibiting certain enzymes associated with inflammatory diseases.

The latest research on Formamidine Hydroiodide has also focused on its applications in materials science. Its unique electronic properties make it a candidate for use in organic semiconductors and light-emitting diodes (OLEDs). The ability to tune the electronic characteristics of materials by incorporating iodinated derivatives like Formamidine Hydroiodide has opened new possibilities for advanced technological applications.

Furthermore, the synthesis and handling of Formamidine Hydroiodide have been optimized to enhance yield and purity. Modern synthetic methodologies have enabled researchers to produce high-purity samples of this compound, facilitating more accurate and reliable experimental outcomes. Techniques such as crystallization, chromatography, and spectroscopic analysis have been refined to ensure the quality of Formamidine Hydroiodide used in research and industrial applications.

The safety profile of Formamidine Hydroiodide is another critical consideration in its application. While it is not classified as a hazardous substance under standard regulatory guidelines, proper handling procedures must be followed to minimize exposure risks. Personal protective equipment (PPE) such as gloves, goggles, and lab coats is recommended when working with this compound. Additionally, adequate ventilation and storage conditions are essential to maintain stability and prevent degradation.

In conclusion, Formamidine Hydroiodide (CAS No. 879643-71-7) is a multifaceted compound with broad applications in pharmaceuticals, bioorganic synthesis, and materials science. Its unique structural features and reactivity make it a valuable tool for researchers seeking to develop novel therapeutic agents and advanced materials. As research continues to uncover new possibilities for this compound, its significance in scientific innovation is likely to grow further.

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