Cas no 873537-27-0 (4-(4-ethyl-1-piperazinyl)-3-fluoro-benzenamine)

4-(4-ethyl-1-piperazinyl)-3-fluoro-benzenamine is a synthetic organic compound with significant potential in pharmaceutical research. It features a piperazine ring, which enhances its solubility and bioavailability. The 3-fluoro group provides distinct electronic properties, making it a valuable tool for medicinal chemistry. This compound is suitable for drug discovery and development due to its unique structural features and potential for interaction with biological targets.
4-(4-ethyl-1-piperazinyl)-3-fluoro-benzenamine structure
873537-27-0 structure
Product Name:4-(4-ethyl-1-piperazinyl)-3-fluoro-benzenamine
CAS No:873537-27-0
MF:C12H18FN3
MW:223.28982591629
MDL:MFCD08699561
CID:1073011
PubChem ID:10751575
Update Time:2025-07-22

4-(4-ethyl-1-piperazinyl)-3-fluoro-benzenamine Chemical and Physical Properties

Names and Identifiers

    • 4-(4-Ethyl-1-piperazinyl)-3-fluoro-benzenamine
    • 3-fluoro-4-(4-ethylpiperazin-1-yl)aniline
    • 4-(4-Ethylpiperazin-1-yl)-3-fluoroaniline
    • 4-(4-Ethyl-1-piperazinyl)-3-fluoroaniline
    • 4-(4-ethyl-piperazin-1-yl)-3-fluoro-phenylamine
    • 4-(4-ethylpiperazinyl)-3-fluorophenylamine
    • C12H18FN3
    • IRLDCHVGDGNGFK-UHFFFAOYSA-N
    • STL412500
    • SBB027113
    • PB32660
    • AK165344
    • ST096041
    • BC4172403
    • Y4421
    • 4-(4
    • 4-(4-Ethyl-1-piperazinyl)-3-fluorobenzenamine (ACI)
    • 4-(4-ethyl-1-piperazinyl)-3-fluoro-benzenamine
    • MDL： MFCD08699561
    • Inchi： 1S/C12H18FN3/c1-2-15-5-7-16(8-6-15)12-4-3-10(14)9-11(12)13/h3-4,9H,2,5-8,14H2,1H3
    • InChI Key： IRLDCHVGDGNGFK-UHFFFAOYSA-N
    • SMILES： FC1C(N2CCN(CC)CC2)=CC=C(N)C=1

Computed Properties

  • Exact Mass: 223.14800
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 16
  • Rotatable Bond Count: 2
  • Complexity: 216
  • Topological Polar Surface Area: 32.5

Experimental Properties

  • PSA: 32.50000
  • LogP: 2.13390

4-(4-ethyl-1-piperazinyl)-3-fluoro-benzenamine Customs Data

  • HS CODE：2933599090
  • Customs Data：

    China Customs Code:

    2933599090

    Overview:

    2933599090. Other compounds with pyrimidine ring in structure(Including other compounds with piperazine ring on the structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

4-(4-ethyl-1-piperazinyl)-3-fluoro-benzenamine Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Alichem
A139004277-5g
4-(4-Ethylpiperazin-1-yl)-3-fluoroaniline
 873537-27-0 98%
5g
 $164.16 2023-08-31
Alichem
A139004277-25g
4-(4-Ethylpiperazin-1-yl)-3-fluoroaniline
 873537-27-0 98%
25g
 $457.00 2023-08-31
Chemenu
CM105022-10g
4-(4-ethyl-1-piperazinyl)-3-fluoro-benzenamine
 873537-27-0 95+%
10g
 $216 2021-08-06
Chemenu
CM105022-25g
4-(4-ethyl-1-piperazinyl)-3-fluoro-benzenamine
 873537-27-0 95+%
25g
 $385 2021-08-06
TRC
E925873-100mg
4-(4-Ethylpiperazin-1-yl)-3-fluoroaniline
 873537-27-0
100mg
 $64.00 2023-05-18
TRC
E925873-250mg
4-(4-Ethylpiperazin-1-yl)-3-fluoroaniline
 873537-27-0
250mg
 $75.00 2023-05-18
TRC
E925873-500mg
4-(4-Ethylpiperazin-1-yl)-3-fluoroaniline
 873537-27-0
500mg
 $87.00 2023-05-18
TRC
E925873-1g
4-(4-Ethylpiperazin-1-yl)-3-fluoroaniline
 873537-27-0
1g
 $98.00 2023-05-18
SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd.
E854749-1g
4-(4-Ethyl-1-piperazinyl)-3-fluoro-benzenamine
 873537-27-0 95%
1g
 1,139.00 2021-05-17
CHENG DOU FEI BO YI YAO Technology Co., Ltd.
FB08359-250g
4-(4-ethyl-1-piperazinyl)-3-fluoro-benzenamine
 873537-27-0 95%
250g
 $700 2023-09-07

4-(4-ethyl-1-piperazinyl)-3-fluoro-benzenamine Production Method

Production Method 1

Reaction Conditions
1.1 Reagents: Potassium carbonate Solvents: Dimethyl sulfoxide ;  12 h, 90 °C
2.1 Reagents: Hydrogen Catalysts: Palladium Solvents: Methanol ,  Ethyl acetate ;  6 h, 100 psi, rt
Reference
Design, synthesis and antitubercular evaluation of novel series of N-[4-(piperazin-1-yl)phenyl]cinnamamide derivatives
Patel, Kavitkumar N.; et al, European Journal of Medicinal Chemistry, 2014, 75, 43-56

Production Method 2

Reaction Conditions
1.1 Reagents: Hydrogen Catalysts: Palladium Solvents: Methanol ,  Ethyl acetate ;  6 h, 100 psi, rt
Reference
Design, synthesis and antitubercular evaluation of novel series of N-[4-(piperazin-1-yl)phenyl]cinnamamide derivatives
Patel, Kavitkumar N.; et al, European Journal of Medicinal Chemistry, 2014, 75, 43-56

4-(4-ethyl-1-piperazinyl)-3-fluoro-benzenamine Raw materials

4-(4-ethyl-1-piperazinyl)-3-fluoro-benzenamine Preparation Products

4-(4-ethyl-1-piperazinyl)-3-fluoro-benzenamine Related Literature

Related Categories

873537-27-0 (4-(4-ethyl-1-piperazinyl)-3-fluoro-benzenamine) Related Products

Recommended suppliers
Zhejiang Brunova Technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Zhejiang Brunova Technology Co., Ltd.
PRIBOLAB PTE.LTD
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
PRIBOLAB PTE.LTD
Shandong Jing Kun Chemical Co.,Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Shandong Jing Kun Chemical Co.,Ltd.
鉅瀾化工科技(青島)有限公司
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
鉅瀾化工科技(青島)有限公司
Handan Zechi Trading Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk