Cas no 876379-86-1 (1-(2,3-difluorophenyl)piperazine)
1-(2,3-Difluorophenyl)piperazine is a fluorinated phenylpiperazine derivative with potential applications in pharmaceutical and chemical research. Its structure features a piperazine ring substituted with a 2,3-difluorophenyl group, offering unique electronic and steric properties that may influence binding affinity in receptor studies. The difluorination enhances metabolic stability and lipophilicity, making it a valuable intermediate in medicinal chemistry for the development of bioactive compounds. This compound is particularly useful in the synthesis of ligands targeting serotonin and dopamine receptors. High purity and well-defined synthesis routes ensure reproducibility for research applications. Its stability under standard laboratory conditions further supports its utility in exploratory and developmental studies.
876379-86-1 structure
Product Name:1-(2,3-difluorophenyl)piperazine
CAS No:876379-86-1
MF:C10H12F2N2
MW:198.212489128113
CID:844870
PubChem ID:11593619
Update Time:2025-06-09
1-(2,3-difluorophenyl)piperazine Chemical and Physical Properties
Names and Identifiers
-
- 1-(2,3-difluorophenyl)piperazine
- AKOS008145183
- SCHEMBL1441614
- 876379-86-1
- 1-(2,3-Difluorophenyl)piperazine, AldrichCPR
- 2,3-difluorophenylpiperazine
- XJPVUJYLKOZVMH-UHFFFAOYSA-N
- EN300-77082
- GS1288
- Z756095110
-
- Inchi： 1S/C10H12F2N2/c11-8-2-1-3-9(10(8)12)14-6-4-13-5-7-14/h1-3,13H,4-7H2
- InChI Key： XJPVUJYLKOZVMH-UHFFFAOYSA-N
- SMILES： FC1C(=CC=CC=1N1CCNCC1)F
Computed Properties
- Exact Mass: 198.09685472g/mol
- Monoisotopic Mass: 198.09685472g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 14
- Rotatable Bond Count: 1
- Complexity: 183
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 1.6
- Topological Polar Surface Area: 15.3?2
1-(2,3-difluorophenyl)piperazine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | D458220-10mg |
1-(2,3-difluorophenyl)piperazine |
876379-86-1 | 10mg |
$ 70.00 | 2022-06-05 | ||
| TRC | D458220-50mg |
1-(2,3-difluorophenyl)piperazine |
876379-86-1 | 50mg |
$ 210.00 | 2022-06-05 | ||
| TRC | D458220-100mg |
1-(2,3-difluorophenyl)piperazine |
876379-86-1 | 100mg |
$ 340.00 | 2022-06-05 | ||
| Enamine | EN300-77082-0.05g |
1-(2,3-difluorophenyl)piperazine |
876379-86-1 | 0.05g |
$202.0 | 2023-02-12 | ||
| Enamine | EN300-77082-0.1g |
1-(2,3-difluorophenyl)piperazine |
876379-86-1 | 0.1g |
$301.0 | 2023-02-12 | ||
| Enamine | EN300-77082-0.25g |
1-(2,3-difluorophenyl)piperazine |
876379-86-1 | 0.25g |
$431.0 | 2023-02-12 | ||
| Enamine | EN300-77082-0.5g |
1-(2,3-difluorophenyl)piperazine |
876379-86-1 | 0.5g |
$679.0 | 2023-02-12 | ||
| Enamine | EN300-77082-1.0g |
1-(2,3-difluorophenyl)piperazine |
876379-86-1 | 1.0g |
$871.0 | 2023-02-12 | ||
| Enamine | EN300-77082-2.5g |
1-(2,3-difluorophenyl)piperazine |
876379-86-1 | 2.5g |
$1707.0 | 2023-02-12 | ||
| Enamine | EN300-77082-5.0g |
1-(2,3-difluorophenyl)piperazine |
876379-86-1 | 5.0g |
$2525.0 | 2023-02-12 |
1-(2,3-difluorophenyl)piperazine Related Literature
-
Qiao Song,Angela Bamesberger,Lingyun Yang,Haley Houtwed,Haishi Cao Analyst, 2014,139, 3588-3592
-
Helga Garcia,Rui Ferreira,Marija Petkovic,Jamie L. Ferguson,Maria C. Leit?o,H. Q. Nimal Gunaratne,Luís Paulo N. Rebelo Green Chem., 2010,12, 367-369
-
Bo Wei,Zhenyu Liu,Chen Xie,Shu Yang,Wentao Tang,Aiwei Gu,Wing-Tak Wong,Ka-Leung Wong J. Mater. Chem. C, 2015,3, 12322-12327
-
Shaun D. Wong,Edward I. Solomon Dalton Trans., 2014,43, 17567-17577
876379-86-1 (1-(2,3-difluorophenyl)piperazine) Related Products
- 255893-57-3(1-(3,4-Difluorophenyl)piperazine)
- 115761-79-0(1-(2,4-Difluorophenyl)piperazine)
- 1011-15-0(1-(2-Fluorophenyl)piperazine)
- 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
- 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
- 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
- 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
- 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
- 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
- 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
Recommended suppliers
Zhejiang Brunova Technology Co., Ltd.
Gold Member
Audited Supplier
CN Supplier
Bulk
Shenzhen GeneSeqTools Bioscience & Technology Co. Ltd.
Gold Member
Audited Supplier
CN Supplier
Reagent
鉅瀾化工科技(青島)有限公司
Gold Member
Audited Supplier
CN Supplier
Bulk
Nantong Boya Environmental Protection Technology Co., Ltd
Gold Member
Audited Supplier
CN Supplier
Bulk
煙臺朗裕新材料科技有限公司
Gold Member
Audited Supplier
CN Supplier
Reagent