Cas no 86770-74-3 (Amino-PEG4-alcohol)

Amino-PEG4-alcohol structure
Amino-PEG4-alcohol structure
Product Name:Amino-PEG4-alcohol
CAS No:86770-74-3
MF:C8H19NO4
MW:193.24076294899
MDL:MFCD01752874
CID:725658
PubChem ID:160103
Update Time:2024-10-26

Amino-PEG4-alcohol Chemical and Physical Properties

Names and Identifiers

    • 2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)ethanol
    • 2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)-ethano
    • 2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]-ethano
    • t4egma
    • 2-[2-AMINOETHOXY]-ETHOXY-ETHOXY-ETHANOL
    • H2N-PEG4-OH
    • 1-Amino-3,6,9-trioxaundecanyl-11-ol
    • (PEO)4-MONO-AMINE
    • 2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethanol
    • Amino-PEG4-alcohol
    • Ethanol,2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]-
    • H2N-4-OH
    • 2-(2-(2-(2-Hydroxyethoxy)ethoxy)ethoxy)ethylamine
    • Tetraethylene glycol monoamine
    • Ethanol, 2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]-
    • Ethanol, 2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)-
    • 2-{2-[2-(2-aminoethoxy)ethoxy]ethoxy}ethan-1-ol
    • 2-{2-[2-(2-aminoethoxy)ethoxy]ethoxy}ethanol
    • 2-[2-(2-[2-aminoethoxy]ethoxy)ethoxy]ethanol
    • Amino-dPEG(R)4-OH
    • B
    • 2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethanol (ACI)
    • 11-Amino-3,6,9-trioxaundecanol
    • 2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)ethan-1-ol
    • 2-[2-[2-(2-Hydroxyethoxy)ethoxy]ethoxy]ethylamine
    • MFCD00286223
    • C8H19NO4
    • EN300-1589200
    • LCZC2381
    • MFCD01752874
    • ZB1004
    • CS-W008005
    • HY-W008005
    • 2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethanol; T4EGMA; Tetraethylene Glycol Monoamine;1-Amino-3,6,9-trioxaundecanyl-11-ol
    • AKOS005266471
    • SY059481
    • 86770-74-3
    • GS-5865
    • DTXSID5072933
    • DA-70792
    • BP-20589
    • SCHEMBL914004
    • 11-Amino-3,6,9-trioxa-undecanol
    • MDL： MFCD01752874
    • Inchi： 1S/C8H19NO4/c9-1-3-11-5-7-13-8-6-12-4-2-10/h10H,1-9H2
    • InChI Key： ANOJXMUSDYSKET-UHFFFAOYSA-N
    • SMILES： OCCOCCOCCOCCN

Computed Properties

  • Exact Mass: 193.13100
  • Monoisotopic Mass: 193.13140809 g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 5
  • Heavy Atom Count: 13
  • Rotatable Bond Count: 10
  • Complexity: 92.2
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 73.9
  • Molecular Weight: 193.24
  • XLogP3: -1.8

Experimental Properties

  • Color/Form: Yellowish oily
  • Density: 1.068±0.06 g/cm3 (20 oC 760 Torr),
  • Boiling Point: 301.6°C at 760 mmHg
  • Flash Point: 136.2°C
  • Refractive Index: 1.458
  • Solubility: Soluble (999 g/l) (25 o C),
  • PSA: 73.94000
  • LogP: -0.31250
  • Sensitiveness: Easily absorb moisture

Amino-PEG4-alcohol Security Information

  • Hazard Statement： H315-H319-H335
  • Hazardous Material transportation number：NONH for all modes of transport
  • Storage Condition：?20°C

Amino-PEG4-alcohol Customs Data

  • HS CODE：2922509090
  • Customs Data：

    China Customs Code:

    2922509090

    Overview:

    2922509090. Other amino alcohol phenols\Amino acid phenols and other oxygenated amino compounds. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:AB. MFN tariff:6.5%. general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to, The color of ethanolamine and its salt should be reported, The package of ethanolamine and its salt shall be declared

    Regulatory conditions:

    A.Customs clearance form for Inbound Goods
    B.Customs clearance form for outbound goods

    Inspection and quarantine category:

    R.Sanitary supervision and inspection of imported food
    S.Sanitary supervision and inspection of exported food

    Summary:

    2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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Amino-PEG4-alcohol Production Method

Production Method 1

Reaction Conditions
1.1 Reagents: Trifluoroacetic acid Solvents: Dichloromethane ;  rt
Reference
Development of a long acting human growth hormone analog suitable for once a week dosing
Palanki, Moorthy S. S.; et al, Bioorganic & Medicinal Chemistry Letters, 2013, 23(2), 402-406

Production Method 2

Reaction Conditions
1.1 Reagents: Hydrogen Catalysts: Palladium Solvents: Ethanol ;  18 h, 0.8 MPa, 100 °C
Reference
Surface Modification of GC and HOPG with Diazonium, Amine, Azide, and Olefin Derivatives
Tanaka, Mutsuo; et al, Langmuir, 2011, 27(1), 170-178

Production Method 3

Reaction Conditions
1.1 Reagents: Triethylamine Solvents: Acetonitrile ;  2 h, 60 °C
1.2 Reagents: 1-Ethyl-3-(3′-dimethylaminopropyl)carbodiimide ,  N-Hydroxysuccinimide Solvents: Acetonitrile ;  2 h, rt
1.3 Solvents: Acetonitrile ;  6 h, rt
Reference
Enhanced Uptake of Porous Silica Microparticles by Bifunctional Surface Modification with a Targeting Antibody and a Biocompatible Polymer
Cheng, Kai; et al, ACS Applied Materials & Interfaces, 2010, 2(9), 2489-2495

Production Method 4

Reaction Conditions
1.1 Reagents: Hydrogen ,  Hydrochloric acid Catalysts: Palladium Solvents: Ethanol
Reference
Synthesis of a fluorescent amphiphilic molecule for interface visualization
Pere-Gigante, A.; et al, Recents Progres en Genie des Procedes, 2001, 15(84), 69-76

Production Method 5

Reaction Conditions
1.1 Reagents: Hydrogen ,  Hydrochloric acid Catalysts: Palladium Solvents: Methanol ;  17 h, rt
Reference
Ligand-phospholipid conjugation: A versatile strategy for developing long-acting ligands that bind to membrane proteins by restricting the subcellular localization of the ligand
Kawamura, Shuhei; et al, Journal of Medicinal Chemistry, 2018, 61(9), 4020-4029

Production Method 6

Reaction Conditions
1.1 Reagents: Triethylamine Solvents: Dichloromethane ;  2 h, 0 °C; overnight, rt
1.2 Solvents: Water ;  rt
2.1 Reagents: Sodium azide Solvents: Acetonitrile ;  36 h, 100 °C; 100 °C → rt
2.2 Solvents: Water ;  rt
3.1 Reagents: Hydrogen Catalysts: Acetic acid ,  Palladium Solvents: Tetrahydrofuran ;  4 h, rt
Reference
Identification of Pyruvate Carboxylase as the Cellular Target of Natural Bibenzyls with Potent Anticancer Activity against Hepatocellular Carcinoma via Metabolic Reprogramming
Sheng, Yuwen; et al, Journal of Medicinal Chemistry, 2022, 65(1), 460-484

Production Method 7

Reaction Conditions
1.1 Solvents: Toluene ;  24 h, 110 °C; 110 °C → rt
1.2 Solvents: Dichloromethane ;  6 h, rt
1.3 Solvents: Glycine ,  Water ;  30 min, rt
1.4 Reagents: Dithiothreitol Solvents: Ethanol ;  4 h, rt
1.5 Solvents: Acetonitrile ,  Water ;  3 h, rt
2.1 Reagents: Triethylamine Solvents: Acetonitrile ;  2 h, 60 °C
2.2 Reagents: 1-Ethyl-3-(3′-dimethylaminopropyl)carbodiimide ,  N-Hydroxysuccinimide Solvents: Acetonitrile ;  2 h, rt
2.3 Solvents: Acetonitrile ;  6 h, rt
Reference
Enhanced Uptake of Porous Silica Microparticles by Bifunctional Surface Modification with a Targeting Antibody and a Biocompatible Polymer
Cheng, Kai; et al, ACS Applied Materials & Interfaces, 2010, 2(9), 2489-2495

Production Method 8

Reaction Conditions
1.1 Reagents: Tosyl chloride ,  Triethylamine
1.2 Reagents: Sodium azide
1.3 Reagents: Triphenylphosphine
Reference
Site-Specific Protein Modification with a Dirhodium Metallopeptide Catalyst
Chen, Zhen; et al, ACS Chemical Biology, 2011, 6(9), 920-925

Production Method 9

Reaction Conditions
1.1 Reagents: Hydrazine hydrate (1:1) Solvents: Ethanol ;  overnight, reflux
1.2 Reagents: Hydrochloric acid Solvents: Water ;  acidified
Reference
Strapped-Porphyrin-Based Molecular Turnstiles
Lang, Thomas; et al, Chemistry - A European Journal, 2012, 18(33), 10419-10426

Production Method 10

Reaction Conditions
1.1 Reagents: Hydrazine hydrate (1:1) Solvents: Ethanol ;  2.5 h, 80 °C; 85 °C → rt
1.2 Reagents: Hydrochloric acid Solvents: Water ;  rt
1.3 Reagents: Sodium hydroxide Solvents: Water ;  20 min, pH 11, rt
Reference
Directed Interactions of Block Copolypept(o)ides with Mannose-binding Receptors: PeptoMicelles Targeted to Cells of the Innate Immune System
Heller, Philipp; et al, Macromolecular Bioscience, 2015, 15(1), 63-73

Production Method 11

Reaction Conditions
1.1 24 h, 120 °C; cooled
1.2 Reagents: Sodium hydroxide ;  12 h, 120 °C
2.1 Reagents: Hydrogen Catalysts: Palladium Solvents: Ethanol ;  18 h, 0.8 MPa, 100 °C
Reference
Surface Modification of GC and HOPG with Diazonium, Amine, Azide, and Olefin Derivatives
Tanaka, Mutsuo; et al, Langmuir, 2011, 27(1), 170-178

Production Method 12

Reaction Conditions
1.1 Solvents: Dimethylformamide ;  10 h, 150 °C; 8 h, rt
2.1 Reagents: Hydrazine hydrate (1:1) Solvents: Ethanol ;  2.5 h, 80 °C; 85 °C → rt
2.2 Reagents: Hydrochloric acid Solvents: Water ;  rt
2.3 Reagents: Sodium hydroxide Solvents: Water ;  20 min, pH 11, rt
Reference
Directed Interactions of Block Copolypept(o)ides with Mannose-binding Receptors: PeptoMicelles Targeted to Cells of the Innate Immune System
Heller, Philipp; et al, Macromolecular Bioscience, 2015, 15(1), 63-73

Production Method 13

Reaction Conditions
1.1 Reagents: Sodium azide Solvents: Dimethylformamide ;  16 h, 50 °C
2.1 Reagents: Hydrogen ,  Hydrochloric acid Catalysts: Palladium Solvents: Methanol ;  17 h, rt
Reference
Ligand-phospholipid conjugation: A versatile strategy for developing long-acting ligands that bind to membrane proteins by restricting the subcellular localization of the ligand
Kawamura, Shuhei; et al, Journal of Medicinal Chemistry, 2018, 61(9), 4020-4029

Production Method 14

Reaction Conditions
1.1 Solvents: Dimethylformamide ;  overnight, 120 °C
2.1 Reagents: Hydrazine hydrate (1:1) Solvents: Ethanol ;  overnight, reflux
2.2 Reagents: Hydrochloric acid Solvents: Water ;  acidified
Reference
Strapped-Porphyrin-Based Molecular Turnstiles
Lang, Thomas; et al, Chemistry - A European Journal, 2012, 18(33), 10419-10426

Production Method 15

Reaction Conditions
1.1 Reagents: Sodium azide Solvents: Dimethylformamide
2.1 Reagents: Hydrogen ,  Hydrochloric acid Catalysts: Palladium Solvents: Ethanol
Reference
Synthesis of a fluorescent amphiphilic molecule for interface visualization
Pere-Gigante, A.; et al, Recents Progres en Genie des Procedes, 2001, 15(84), 69-76

Amino-PEG4-alcohol Raw materials

Amino-PEG4-alcohol Preparation Products

Amino-PEG4-alcohol Suppliers

Amadis Chemical Company Limited
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(CAS:86770-74-3)Amino-PEG4-alcohol
Order Number:A863045
Stock Status:in Stock
Quantity:25g/100g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 08:38
Price ($):219.0/870.0
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:86770-74-3)1-氨基-3,6,9-三噁-11-十一醇
Order Number:LE20751997
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:48
Price ($):discuss personally

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Amadis Chemical Company Limited
(CAS:86770-74-3)Amino-PEG4-alcohol
A863045
Purity:99%/99%
Quantity:25g/100g
Price ($):219.0/870.0
Email
Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:86770-74-3)1-氨基-3,6,9-三噁-11-十一醇
LE20751997
Purity:99%
Quantity:25KG,200KG,1000KG
Price ($):Inquiry
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