Cas no 112-60-7 (Tetraethylene glycol)

Tetraethylene glycol (TEG) is a high-purity, water-soluble polyether glycol with the molecular formula C?H??O?. It is commonly used as a solvent, plasticizer, and intermediate in organic synthesis. TEG exhibits excellent hygroscopicity, thermal stability, and low volatility, making it suitable for applications in gas dehydration, lubricants, and coatings. Its compatibility with polar and non-polar compounds enhances its utility in formulations requiring controlled solubility. Additionally, TEG serves as a key component in the production of polyurethanes and other specialty polymers. Its stable chemical properties and low toxicity ensure reliable performance in industrial and laboratory settings.
Tetraethylene glycol structure
Tetraethylene glycol structure
Product Name:Tetraethylene glycol
CAS No:112-60-7
MF:C8H18O5
MW:194.225523471832
MDL:MFCD00002879
CID:35753
PubChem ID:8200
Update Time:2025-06-14

Tetraethylene glycol Chemical and Physical Properties

Names and Identifiers

    • 2,2'-((Oxybis(ethane-2,1-diyl))bis(oxy))diethanol
    • tetragol
    • tetraglycolTetraethylene glycol
    • Tetraethyleneglycol
    • Tetra Ethylene Glycol (TTEG)
    • Bis[2-(2-hydroxyethoxy)ethyl] ether
    • 2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethanol
    • Ethyl acetate
    • 3,6,9-Trioxaundecane-1,11-diol
    • Hi-Dry
    • OH-PEG4-OH
    • TETRAGLYCOL
    • LIPOXOL 200
    • TetraHthylenglykol
    • Tetraethylene glyco
    • Tetracthyleneglycol
    • tetraethylenegylcol
    • 25322-68-33,6,9-
    • TETRAETHYLENE GLYCOL
    • Carbitol, diethyl
    • Ethanol, 2,2'-[oxybis(2,1-ethanediyloxy)]bis-
    • Tetra(ethylene glycol)
    • 2,2'-[oxybis(ethane-2,1-diyloxy)]diethanol
    • Ethanol, 2,2'-(oxybis(ethyleneoxy))di-
    • PEG-4
    • 2,2'-[oxybis(2,1-ethanediyloxy)]diethanol
    • UWHCK
    • UWHCKJMYHZGTIT-UHFFFAOYSA-N
    • 2-[2-[2-(2-hydroxye
    • UNII-R95B8J264J
    • BIS-[2-(2-HYDROXYETHOXY) ETHYL ETHER
    • HiDry
    • NSC-1262
    • 2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)ethan-1-ol
    • Ethanol, 2,2'(oxybis(2,1ethanediyloxy))bis
    • 127821-00-5
    • T0099
    • EC 203-989-9
    • NCGC00164038-01
    • DS-17878
    • SCHEMBL15101
    • WLN: Q2O2O2O2Q
    • DA-69618
    • Q12430182
    • 2,2'-(oxybis(ethane-2,1-diyloxy))diethanol
    • NCGC00259178-01
    • HO-PEG4-OH
    • Bis[2-(2-hydroxyethoxy)ethyl] Ether(Tetraethylene Glycol)
    • bis[2-(2-hydroxyethoxy)ethyl]ether
    • NCGC00257035-01
    • 112-60-7
    • PG4
    • 9004-76-6
    • Tetraethylene glycol, 99%
    • 2-(2-(2-(2-Hydroxyethoxy)ethoxy)ethoxy)ethanol
    • BIS-(2-(2-HYDROXYETHOXY) ETHYL ETHER
    • 2-(2-[2-(2-Hydroxyethoxy)ethoxy]ethoxy)ethanol
    • EN300-19499
    • 2-(2-(2-(2-hydroxy-ethoxy)ethoxy)ethoxy)ethanol
    • 125481-05-2
    • tetra-ethylene glycol
    • NS00009833
    • W18472
    • PEG-4 [INCI]
    • 2-{2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethoxy}-ethanol
    • Ethanol, 2,2'(oxybis(ethyleneoxy))di
    • HSDB 843
    • CAS-112-60-7
    • HY-W018745
    • J-519899
    • 3,9-Trioxaundecane-1,11-diol
    • BRN 1634320
    • BP-20324
    • STL268854
    • 157299-02-0
    • MFCD00002879
    • AKOS000119933
    • R95B8J264J
    • DTXSID9026922
    • Ethanol, 2,2'-(oxybis(2,1-ethanediyloxy))bis-
    • tetraethylenglycol
    • 3,6,9-Trioxaundecan-1,11-diol
    • 3,6,9-TRIOXAUNDECAN-1, 11-DIOL
    • PROTAC Linker 18
    • EINECS 203-989-9
    • 2,2'-(Oxybis(ethyleneoxy))diethanol
    • CHEMBL1235254
    • DTXCID806922
    • 2,2'-[oxybis(2,1-ethanediyloxy)]bisethanol
    • Tox21_303245
    • Ethanol,2'-[oxybis(ethyleneoxy)]di-
    • 2,2'-(2,2'-oxybis(ethane-2,1-diyl)bis(oxy))diethanol
    • SY010865
    • 1,11-Dihydroxy-3,6,9-trioxaundecane
    • Ethanol,2'-[oxybis(2,1-ethanediyloxy)]bis-
    • Tox21_201629
    • CHEBI:44920
    • 3,6,9Trioxaundecane1,11diol
    • F8889-3081
    • 2,2'-((Oxybis(ethane-2,1-diyl))bis(oxy))diethanol; Ethanol, 2,2'-[oxybis(2,1-ethanediyloxy)]bis-
    • AI3-01838
    • CS-W019531
    • 2,2'-(Oxybis(2,1-ethanediyloxy))diethanol
    • C8H18O5
    • 2-{2-[2-(2-hydroxyethoxy)ethoxy]ethoxy}ethan-1-ol
    • NSC1262
    • 2,2'-((oxybis(ethane-2,1-diyl))bis(oxy))bis(ethan-1-ol)
    • NCGC00164038-02
    • NSC 1262
    • Tetraethylene glycol
    • MDL： MFCD00002879
    • Inchi： 1S/C8H18O5/c9-1-3-11-5-7-13-8-6-12-4-2-10/h9-10H,1-8H2
    • InChI Key： UWHCKJMYHZGTIT-UHFFFAOYSA-N
    • SMILES： OCCOCCOCCOCCO
    • BRN： 1634320

Computed Properties

  • Exact Mass: 194.11500
  • Monoisotopic Mass: 194.115
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 5
  • Heavy Atom Count: 13
  • Rotatable Bond Count: 10
  • Complexity: 78.6
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: -1.6
  • Topological Polar Surface Area: 68.2

Experimental Properties

  • Color/Form: Colorless to light straw colored viscous liquid, easy to absorb moisture.
  • Density: 1.125?g/mL?at 25?°C(lit.)
  • Melting Point: ?5.6?°C (lit.)
  • Boiling Point: 328°C(lit.)
  • Flash Point: Fahrenheit: 359.6 ° f < br / > Celsius: 182 ° C < br / >
  • Refractive Index: n20/D 1.459(lit.)
  • PH: 8.5-9.0 (500g/l, H2O, 20℃)
  • Solubility: 1000g/l
  • Water Partition Coefficient: dissolution
  • Stability/Shelf Life: Stable. Incompatible with strong oxidizing agents, strong bases.
  • PSA: 68.15000
  • LogP: -0.97920
  • Vapor Pressure: <0.01 mmHg
  • Solubility: It is miscible with water and alcohol. Insoluble in benzene, toluene and aliphatic hydrocarbons.

Tetraethylene glycol Security Information

Tetraethylene glycol Customs Data

  • HS CODE：2942000000
  • Customs Data：

    China Customs Code:

    2909499000

    Overview:

    2909499000 Other ether alcohols and their halogenation\sulfonation\Nitrosative or nitrosative derivatives. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:5.5% general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

Tetraethylene glycol Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd.
110175-100G
Tetraethylene glycol
 112-60-7
100g
 ￥649.49 2023-12-10
XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd.
110175-1KG
Tetraethylene glycol
 112-60-7
1kg
 ￥894.62 2023-12-10
XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd.
110175-3KG
Tetraethylene glycol
 112-60-7
3kg
 ￥1565.48 2023-12-10
XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd.
110175-20KG
Tetraethylene glycol
 112-60-7
20kg
 ￥8130.86 2023-12-10
TI XI AI ( SHANG HAI ) HUA CHENG GONG YE FA ZHAN Co., Ltd.
T0099-500G
Tetraethylene Glycol
 112-60-7 >95.0%(GC)
500g
 ￥180.00 2024-04-18
S e l l e c k ZHONG GUO
S1951-100mg
Tetraethylene glycol
 112-60-7
100mg
 ￥970.65 2022-04-26
TRC
B443820-10g
Bis[2-(2-hydroxyethoxy)ethyl] Ether(Tetraethylene Glycol)
 112-60-7
10g
 $ 58.00 2023-09-08
TRC
B443820-50 g
Bis[2-(2-hydroxyethoxy)ethyl] Ether(Tetraethylene Glycol)
 112-60-7
50g
 55.00 2021-08-17
TRC
B443820-100 g
Bis[2-(2-hydroxyethoxy)ethyl] Ether(Tetraethylene Glycol)
 112-60-7
100g
 90.00 2021-08-17
TRC
B443820-250 g
Bis[2-(2-hydroxyethoxy)ethyl] Ether(Tetraethylene Glycol)
 112-60-7
250g
 130.00 2021-08-17

Tetraethylene glycol Suppliers

Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:112-60-7)Bis[2-(2-hydroxyethoxy)ethyl] ether
Order Number:1661536;sfd16664
Stock Status:in Stock
Quantity:Company Customization/200kg
Purity:98%/99.9%
Pricing Information Last Updated:Monday, 14 April 2025 21:49
Price ($):discuss personally
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:112-60-7)Tetraethylene glycol
Order Number:LE15449;LE1661536;LE5776
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:12
Price ($):discuss personally

Tetraethylene glycol Related Literature

Related Categories

Additional information on Tetraethylene glycol

Research Brief on Tetraethylene Glycol (CAS 112-60-7) in Chemical Biology and Pharmaceutical Applications

Tetraethylene glycol (TEG, CAS 112-60-7) is a polyethylene glycol derivative that has garnered significant attention in chemical biology and pharmaceutical research due to its versatile applications. Recent studies have explored its role in drug delivery systems, bioconjugation, and as a solvent or linker in various biochemical processes. This research brief synthesizes the latest findings on TEG, highlighting its potential in advancing therapeutic and diagnostic technologies.

A 2023 study published in the Journal of Medicinal Chemistry investigated TEG's utility as a linker in antibody-drug conjugates (ADCs). The researchers demonstrated that TEG-based linkers exhibit superior stability in physiological conditions compared to traditional PEG linkers, thereby enhancing the pharmacokinetic profiles of ADCs. The study utilized mass spectrometry and NMR spectroscopy to validate the structural integrity of TEG-linked conjugates, underscoring its reliability for targeted cancer therapies.

In another breakthrough, TEG was employed as a key component in the development of hydrogels for controlled drug release. A team from MIT reported in Advanced Materials (2024) that TEG-crosslinked hydrogels displayed tunable degradation rates, enabling sustained release of small-molecule therapeutics over extended periods. This property is particularly advantageous for treating chronic conditions such as diabetes and inflammatory diseases, where consistent drug levels are critical.

Beyond therapeutics, TEG has also been explored in diagnostic applications. A recent Analytical Chemistry paper (2024) described its use as a stabilizing agent in fluorescent probes for real-time imaging of cellular processes. The study found that TEG-modified probes exhibited reduced nonspecific binding and improved signal-to-noise ratios, making them ideal for high-resolution microscopy and in vivo imaging.

Despite these advancements, challenges remain in optimizing TEG's biocompatibility and scalability for industrial production. Ongoing research aims to address these limitations through chemical modifications and novel synthesis protocols. For instance, a preprint on bioRxiv (2024) proposed a green chemistry approach to synthesize TEG derivatives with reduced cytotoxicity, paving the way for safer biomedical applications.

In conclusion, Tetraethylene glycol (112-60-7) continues to emerge as a multifunctional tool in chemical biology and pharmaceuticals. Its applications span drug delivery, diagnostics, and material science, driven by its unique physicochemical properties. Future research should focus on refining its performance metrics and expanding its utility in precision medicine and personalized therapies.

112-60-7 (Tetraethylene glycol) Related Products

Recommended suppliers
Suzhou Senfeida Chemical Co., Ltd
(CAS:112-60-7)Bis[2-(2-hydroxyethoxy)ethyl] ether
1661536;sfd16664
Purity:98%/99.9%
Quantity:Company Customization/200kg
Price ($):Inquiry/Inquiry
Email
Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:112-60-7)Tetraethylene glycol
LE15449;LE1661536;LE5776
Purity:99%/99%/99%
Quantity:25KG,200KG,1000KG/25KG,200KG,1000KG/25KG,200KG,1000KG
Price ($):Inquiry/Inquiry/Inquiry
Email