Cas no 861084-02-8 (2-Bromo-6-methoxyaniline hydrochloride)

2-Bromo-6-methoxyaniline hydrochloride is a halogenated aniline derivative with a methoxy substituent, commonly utilized as an intermediate in organic synthesis and pharmaceutical research. Its key advantages include high purity and stability, making it suitable for precise reactions such as coupling or functional group transformations. The bromo and methoxy groups enhance its reactivity in electrophilic aromatic substitution and metal-catalyzed cross-coupling reactions. The hydrochloride salt form improves solubility in polar solvents, facilitating handling in aqueous or mixed-phase systems. This compound is particularly valuable in the development of agrochemicals, dyes, and bioactive molecules, where controlled reactivity and structural specificity are critical. Proper storage under anhydrous conditions is recommended to maintain integrity.
2-Bromo-6-methoxyaniline hydrochloride structure
861084-02-8 structure
Product Name:2-Bromo-6-methoxyaniline hydrochloride
CAS No:861084-02-8
MF:C7H9BrClNO
MW:238.5094602108
MDL:MFCD24368592
CID:2950518
PubChem ID:75486179
Update Time:2025-10-29

2-Bromo-6-methoxyaniline hydrochloride Chemical and Physical Properties

Names and Identifiers

    • 2-溴-6-甲氧基苯胺鹽酸鹽
    • 2-Bromo-6-methoxyaniline hydrochloride
    • 2-Bromo-6-methoxy-phenylamine hydrochloride
    • 2-bromo-6-methoxyaniline;hydrochloride
    • C7H8BrNO.HCl
    • 1618AJ
    • 2-Bromo-6-methoxyanilinehydrochloride
    • SB39113
    • o-Anisidine, 6-bromo-, -HCl (3CI)
    • MDL: MFCD24368592
    • Inchi: 1S/C7H8BrNO.ClH/c1-10-6-4-2-3-5(8)7(6)9;/h2-4H,9H2,1H3;1H
    • InChI Key: MKCVFGXIGAEFSZ-UHFFFAOYSA-N
    • SMILES: Cl.BrC1C(N)=C(OC)C=CC=1

Computed Properties

  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 1
  • Complexity: 110
  • Topological Polar Surface Area: 35.2

2-Bromo-6-methoxyaniline hydrochloride Pricemore >>

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Additional information on 2-Bromo-6-methoxyaniline hydrochloride

Comprehensive Overview of 2-Bromo-6-methoxyaniline Hydrochloride (CAS No. 861084-02-8)

2-Bromo-6-methoxyaniline hydrochloride (CAS No. 861084-02-8) is a specialized organic compound widely utilized in pharmaceutical and agrochemical research. This compound, characterized by its bromine and methoxy functional groups, serves as a critical intermediate in the synthesis of bioactive molecules. Its unique structural properties make it valuable for developing drug candidates and fine chemicals, aligning with the growing demand for high-purity intermediates in modern laboratories.

The compound's molecular formula and structural features have attracted significant attention in medicinal chemistry, particularly in the design of targeted therapies. Researchers often explore its reactivity in cross-coupling reactions, a hotspot in organic synthesis methodologies. Recent trends in green chemistry have also spurred interest in optimizing its production processes to reduce environmental impact, addressing the industry's shift toward sustainable synthesis.

One of the most frequently searched questions about 2-Bromo-6-methoxyaniline hydrochloride relates to its solubility and stability under various conditions. Studies confirm its solubility in polar solvents like methanol and dimethyl sulfoxide (DMSO), making it suitable for diverse laboratory applications. Additionally, its storage recommendations (e.g., cool, dry environments) are critical for maintaining its integrity, a topic often queried by laboratory technicians.

In the context of pharmaceutical innovation, this compound has been investigated for its potential role in kinase inhibitor development, a trending area in cancer research. Its brominated aromatic ring offers strategic modification sites for structure-activity relationship (SAR) studies, a key focus in drug discovery pipelines. Such applications resonate with current searches on precision medicine and small-molecule therapeutics.

From a supply chain perspective, CAS No. 861084-02-8 is often sourced for custom synthesis projects, reflecting the demand for tailor-made intermediates. Analytical techniques like HPLC and NMR are routinely employed to verify its purity, a detail highly relevant to quality-conscious buyers. This aligns with the broader industry emphasis on certified reference materials and batch-to-batch consistency.

Emerging discussions in chemical databases highlight its utility in heterocyclic compound synthesis, particularly for benzoxazole derivatives. Such derivatives are gaining traction in material science for their luminescent properties, connecting this compound to cutting-edge applications beyond traditional chemistry. This interdisciplinary relevance boosts its visibility in academic literature and patent filings.

In summary, 2-Bromo-6-methoxyaniline hydrochloride (CAS No. 861084-02-8) exemplifies the intersection of synthetic versatility and applied research. Its role in advancing molecular design and process optimization ensures its continued prominence in both industrial and academic settings. As chemical innovation evolves, this compound remains a subject of dynamic exploration, answering contemporary questions in science and technology.

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