• 1. An atom efficient route to N-aryl and N-alkyl pyrrolines by transition metal catalysis?
  Supaporn Sawadjoon,Joseph S. M. Samec Org. Biomol. Chem., 2011,9, 2548-2554
• 2. An automatic determination of thoria in thoria-urania mixtures
  Analyst, 1966,91, 208-210
• 3. An integrated chip for immunofluorescence and its application to analyze lysosomal storage disorders
  Jie Shen,Ying Zhou,Tu Lu,Junya Peng,Zhixiang Lin,Yuhong Pang,Li Yu Lab Chip, 2012,12, 317-324
• 4. An artificial photosynthetic system for photoaccumulation of two electrons on a fused dipyridophenazine (dppz)–pyridoquinolinone ligand?
  Philipp Traber,Stephan Kupfer,Stefanie Gr?fe,Isabelle Baussanne,Martine Demeunynck,Jean-Marie Mouesca,Serge Gambarelli,Vincent Artero,Murielle Chavarot-Kerlidou Chem. Sci., 2018,9, 4152-4159
• 5. An aptasensor for detection of potassium ions based on RecJf exonuclease mediated signal amplification
  Bidou Wang,Xifeng Chen Analyst, 2014,139, 5695-5699

Exploring the Properties and Applications of 2-Bromo-6-Ethoxyaniline

2-Bromo-6-Ethoxyaniline, also known by its CAS number 1072945-59-5, is a brominated aromatic amine compound with significant potential in various chemical and pharmaceutical applications. This compound has been the subject of recent research, particularly in the fields of organic synthesis and drug development. Its unique structure, featuring a bromine atom at the 2-position and an ethoxy group at the 6-position on the aniline ring, makes it a versatile building block for constructing complex molecules.

The synthesis of 2-Bromo-6-Ethoxyaniline involves a multi-step process that typically begins with the bromination of an aniline derivative. Researchers have explored various methods to optimize this process, including the use of catalytic systems and alternative solvents to enhance yield and purity. Recent studies have highlighted the importance of reaction conditions, such as temperature and pH, in determining the selectivity of bromination reactions.

In terms of physical properties, 2-Bromo-6-Ethoxyaniline exhibits a melting point of approximately 180°C and is sparingly soluble in water but dissolves readily in organic solvents like dichloromethane and ethyl acetate. These properties make it suitable for use in both solution-phase and solid-phase synthesis techniques. The compound's stability under thermal and oxidative conditions has also been studied extensively, with findings indicating moderate stability under ambient conditions.

The application of 2-Bromo-6-Ethoxyaniline in drug discovery has garnered significant attention due to its ability to act as a precursor for bioactive compounds. For instance, recent research has demonstrated its utility in synthesizing potential inhibitors for kinases, which are key targets in cancer therapy. The bromine atom at the 2-position serves as a reactive site for further functionalization, enabling the introduction of diverse substituents that can modulate biological activity.

Beyond pharmaceuticals, 2-Bromo-6-Ethoxyaniline has found applications in materials science, particularly in the development of advanced polymers and coatings. Its aromatic structure contributes to high thermal stability, making it a candidate for high-performance materials used in aerospace and electronics industries.

In conclusion, 2-Bromo-6-Ethoxyaniline, with its unique chemical properties and versatile structure, continues to be a focal point for researchers across multiple disciplines. As advancements in synthetic methodologies and material characterization techniques unfold, this compound is poised to play an even more critical role in driving innovation across various sectors.

• 914482-43-2(4-Bromo-2-isopropoxyaniline)
• 5473-01-8(2-Bromo-6-methoxyaniline)
• 88149-47-7(2,4-Dibromo-6-methoxyaniline)
• 68319-86-8((5-bromo-2-ethoxyphenyl)amine hydrochloride)
• 1235451-65-6(5-Bromo-2-(2-bromoethoxy)aniline)
• 57279-73-9(4-bromo-2-ethoxyaniline)
• 197803-53-5(2-\u200bBromo-\u200b4,\u200b6-\u200bdimethoxybenzenamine)
• 116529-46-5(Benzenamine, 2,4-dibromo-6-ethoxy-)
• 946786-59-0(5-Bromo-2-(3-methoxypropoxy)aniline)
• 861084-02-8(2-Bromo-6-methoxyaniline hydrochloride)