Cas no 86099-06-1 (BM-PEG3)

BM-PEG3 structure
BM-PEG3 structure
Product Name:BM-PEG3
CAS No:86099-06-1
MF:C16H20N2O7
MW:352.339204788208
MDL:MFCD01863352
CID:875323
PubChem ID:354335571
Update Time:2024-12-09

BM-PEG3 Chemical and Physical Properties

Names and Identifiers

    • 1,11-Bis(maleimido)tetraethyleneglycol
    • 1,11-Bis(maleimido)-3,6,9-trioxaundecane
    • 1,11-BIS-MALEIMIDOTETRAETHYLENEGLYCOL
    • N,N'-(1,11-Tetraethyleneglycol)bismaleimide
    • 1,11-Bis-Maleimidodriethyleneglycol
    • 1,11-Bis(maleimido)triethylene Glycol
    • BM-PEG3
    • 1,1′-[Oxybis(2,1-ethanediyloxy-2,1-ethanediyl)]bis[1H-pyrrole-2,5-dione] (ACI)
    • 1,11-Bismaleimidotetraethyleneglycol
    • 1-[2-[2-[2-[2-(2,5-Dioxopyrrol-1-yl)ethoxy]ethoxy]ethoxy]ethyl]pyrrole-2,5-dione
    • Bismaleimide PEG3
    • BM(PEG)3
    • N,N′-3,6,9-Trioxadecane-1,11-bismaleimide
    • 1-[2-(2-{2-[2-(2,5-DIOXOPYRROL-1-YL)ETHOXY]ETHOXY}ETHOXY)ETHYL]PYRROLE-2,5-DIONE
    • 1,11-BIS-MALEIMIDO-(PEO)4
    • HY-130898
    • 1,23-Bis(maleimido)heptaethyleneglycol
    • D89154
    • B5668
    • BCP26217
    • 960257-46-9
    • MFCD01863352
    • BM(PEG)3 (1,11-bismaleimido-triethyleneglycol)
    • DTXSID30391539
    • 1,11-Bis-Maleidotetraethyleneglycol
    • SCHEMBL140275
    • CS-0116363
    • 86099-06-1
    • Mal-PEG3-CH2CH2Mal
    • 1,1'-[Oxybis(2,1-ethanediyloxy-2,1-ethanediyl)]bis-1H-pyrrole-2,5-dione
    • AKOS040743079
    • MDL: MFCD01863352
    • Inchi: 1S/C16H20N2O7/c19-13-1-2-14(20)17(13)5-7-23-9-11-25-12-10-24-8-6-18-15(21)3-4-16(18)22/h1-4H,5-12H2
    • InChI Key: OYRSKXCXEFLTEY-UHFFFAOYSA-N
    • SMILES: O=C1N(CCOCCOCCOCCN2C(=O)C=CC2=O)C(=O)C=C1

Computed Properties

  • Exact Mass: 352.12700
  • Monoisotopic Mass: 352.12705098g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 7
  • Heavy Atom Count: 25
  • Rotatable Bond Count: 12
  • Complexity: 499
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: -1.7
  • Topological Polar Surface Area: 102?2

Experimental Properties

  • Density: 1.3±0.1 g/cm3
  • Melting Point: 63.0 to 68.0 deg-C
  • Boiling Point: 526.9±45.0 °C at 760 mmHg
  • Flash Point: 272.5±28.7 °C
  • PSA: 102.45000
  • LogP: -1.23800
  • Vapor Pressure: 0.0±1.4 mmHg at 25°C

BM-PEG3 Pricemore >>

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BM-PEG3 Production Method

Production Method 1

Reaction Conditions
1.1 Reagents: Potassium carbonate Solvents: Dimethylformamide ;  24 h, 50 °C
2.1 Solvents: 1,1,2,2-Tetrachloroethane ;  12 h, 120 °C
Reference
An efficient reverse Diels-Alder approach for the synthesis of N-alkyl bismaleimides
Rao, Venkataramanarao; et al, Tetrahedron Letters, 2013, 54(37), 5011-5013

Production Method 2

Reaction Conditions
1.1 Solvents: 1,1,2,2-Tetrachloroethane ;  12 h, 120 °C
Reference
An efficient reverse Diels-Alder approach for the synthesis of N-alkyl bismaleimides
Rao, Venkataramanarao; et al, Tetrahedron Letters, 2013, 54(37), 5011-5013

Production Method 3

Reaction Conditions
1.1 Solvents: Chloroform ;  8 °C; 2 h, rt
1.2 Reagents: Acetic anhydride ,  Triethylamine ,  Sodium acetate Solvents: Acetone ;  2.5 h, reflux
Reference
Effects of Excluded Volume upon Protein Stability in Covalently Cross-Linked Proteins with Variable Linker Lengths
Kim, Yun Ho; et al, Biochemistry, 2008, 47(33), 8804-8814

Production Method 4

Reaction Conditions
1.1 -
2.1 Solvents: Chloroform ;  8 °C; 2 h, rt
2.2 Reagents: Acetic anhydride ,  Triethylamine ,  Sodium acetate Solvents: Acetone ;  2.5 h, reflux
Reference
Effects of Excluded Volume upon Protein Stability in Covalently Cross-Linked Proteins with Variable Linker Lengths
Kim, Yun Ho; et al, Biochemistry, 2008, 47(33), 8804-8814

Production Method 5

Reaction Conditions
1.1 Reagents: Thionyl chloride
2.1 -
3.1 Solvents: Chloroform ;  8 °C; 2 h, rt
3.2 Reagents: Acetic anhydride ,  Triethylamine ,  Sodium acetate Solvents: Acetone ;  2.5 h, reflux
Reference
Effects of Excluded Volume upon Protein Stability in Covalently Cross-Linked Proteins with Variable Linker Lengths
Kim, Yun Ho; et al, Biochemistry, 2008, 47(33), 8804-8814

BM-PEG3 Raw materials

BM-PEG3 Preparation Products

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