Production Method 1

771-61-9

103321-50-2

86060-86-8

Reaction Conditions

1.1 Reagents: 4-Methylmorpholine Solvents: Dichloromethane ;  10 min, 0 °C; 13.5 h, 0 °C

Reference

Silicon-based hydrophobic tags applied in liquid-phase peptide synthesis: Protected DRGN-1 and poly alanine chain synthesis

Wu, An; Ramakrishna, Isai; Hattori, Tomohiro; Yamamoto, Hisashi, Organic & Biomolecular Chemistry, 2022, 20(44), 8685-8692

Production Method 2

771-61-9

35661-39-3

86060-86-8

Reaction Conditions

1.1 Reagents: Diisopropylethylamine ,  Morpholinium, 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methyl-, 4-methylbenzenesul… Solvents: Dichloromethane ;  30 min, 0 °C
1.2 Reagents: Diisopropylethylamine ;  2 h, 0 °C; overnight, rt

Reference

4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium toluene-4-sulfonate (DMT/NMM/TsO-) universal coupling reagent for synthesis in solution

Fraczyk, Justyna; Kaminski, Zbigniew J.; Katarzynska, Joanna; Kolesinska, Beata, Helvetica Chimica Acta, 2018, 101(1),

Production Method 3

771-61-9

35661-39-3

86060-86-8

Reaction Conditions

1.1 Reagents: Dicyclohexylcarbodiimide Solvents: Ethyl acetate ;  2 h, 0 °C

Reference

Pentafluorophenol

Jones, Keith; DeAmicis, Carl, e-EROS Encyclopedia of Reagents for Organic Synthesis, 2009, 1, 1-9

Production Method 4

771-61-9

35661-39-3

86060-86-8

Reaction Conditions

1.1 Reagents: Dicyclohexylcarbodiimide Solvents: Ethyl acetate

Reference

9-Fluorenylmethyl pentafluorophenyl carbonate as a useful reagent for the preparation of N-[(9-fluorenylmethoxy)carbonyl] amino acids and their pentafluorophenyl esters

Schon, Istvan; Kisfaludy, Lajos, Synthesis, 1986, (4), 303-5

Fmoc-Ala-OPfp Raw materials

• Pentafluorophenol
• Fmoc-l-alanyl Chloride
• Fmoc-Ala-OH

Fmoc-Ala-OPfp Preparation Products

• Fmoc-Ala-OPfp (86060-86-8)

• 1. Excitation energies from ground-state density-functionals by means of generator coordinates
  A. B. F. da Silva,K. Capelle Phys. Chem. Chem. Phys., 2009,11, 4564-4569
• 2. Dissociation of large gaseous serine clusters produces abundant protonated serine octamer
  Jacob S. Jordan,Evan R. Williams Analyst, 2021,146, 2617-2625
• 3. Esterase-responsive polymeric prodrug-based tumor targeting nanoparticles for improved anti-tumor performance against colon cancer?
  Gang Pan,Yi-jie Bao,Jie Xu,Tao Liu,Cheng Liu,Yan-yan Qiu,Xiao-jing Shi,Hui Yu,Ting-ting Jia,Xia Yuan,Ze-ting Yuan,Yi-jun Cao RSC Adv., 2016,6, 42109-42119
• 4. Distinction of trans–cis photoisomers with comparable optical properties in multiple-state photochromic systems – examining a molecule with three azobenzenes via in situ irradiation NMR spectroscopy?
  Jonas Kind,Lukas Kaltschnee,Martin Leyendecker,Christina M. Thiele Chem. Commun., 2016,52, 12506-12509
• 5. Fe3O4/PEG-SO3H as a heterogeneous and magnetically-recyclable nanocatalyst for the oxidation of sulfides to sulfones or sulfoxides
  Saeideh Mirfakhraei,Malak Hekmati,Fereshteh Hosseini Eshbala,Hojat Veisi New J. Chem., 2018,42, 1757-1761

• Solvents and Organic Chemicals Organic Compounds Acids/Esters

• 86060-85-7(Fmoc-Gly-OPfp)
• 29022-11-5(Fmoc-Gly-OH)
• 121593-77-9(Fmoc-Nle-OPfp)
• 53298-33-2(Fmoc-Cys(Bzl)-OH)
• 35661-60-0(Fmoc-L-Leu-OH)
• 35665-38-4(Fmoc-Gly-Gly-OH)
• 4326-36-7(Boc-L-Tyrosine methyl ester)
• 159631-29-5(FMOC-SAR-OPFP)
• 35661-39-3(Fmoc-Ala-OH)
• 35661-40-6(Fmoc-Phe-OH)