Cas no 852385-13-8 (6-Methyl-7-O-methylaromadendrin)

6-Methyl-7-O-methylaromadendrin is a flavonoid derivative characterized by its methylated hydroxyl groups, which enhance its stability and bioavailability compared to non-methylated analogs. This compound exhibits potential as a biochemical intermediate due to its unique structural modifications, which may influence its reactivity and interaction with biological targets. Its methylated structure also improves solubility in organic solvents, facilitating its use in synthetic and analytical applications. Research suggests it may possess bioactive properties, making it of interest for pharmacological studies. The compound's defined chemical structure allows for precise characterization, supporting its utility in specialized chemical and biomedical research contexts.
6-Methyl-7-O-methylaromadendrin structure
852385-13-8 structure
Product Name:6-Methyl-7-O-methylaromadendrin
CAS No:852385-13-8
MF:C17H16O6
MW:316.305345535278
CID:1080699
PubChem ID:102004632
Update Time:2025-06-10

6-Methyl-7-O-methylaromadendrin Chemical and Physical Properties

Names and Identifiers

    • 6-Methyl-7-O-methylaromadendrin
    • [ "" ]
    • (2S,3S)-2,3-Dihydro-3,5-dihydroxy-2-(4-hydroxyphenyl)-7-methoxy-6-methyl-4H-1-benzopyran-4-one (ACI)
    • C-6,O-7-Dimethylaromadendrin
    • CHEMBL4206408
    • 852385-13-8
    • (2R,3R)-3,5-dihydroxy-2-(4-hydroxyphenyl)-7-methoxy-6-methyl-2,3-dihydrochromen-4-one
    • FS-8685
    • (2R,3R)-3,5-Dihydroxy-2-(4-hydroxyphenyl)-7-methoxy-6-methylchroman-4-one
    • Inchi: 1S/C17H16O6/c1-8-11(22-2)7-12-13(14(8)19)15(20)16(21)17(23-12)9-3-5-10(18)6-4-9/h3-7,16-19,21H,1-2H3/t16-,17+/m1/s1
    • InChI Key: MGHMBAZWBKOORJ-SJORKVTESA-N
    • SMILES: O=C1[C@@H](O)[C@H](C2C=CC(O)=CC=2)OC2C=C(C(=C(C1=2)O)C)OC

Computed Properties

  • Exact Mass: 316.09500
  • Monoisotopic Mass: 316.09468823g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 3
  • Hydrogen Bond Acceptor Count: 6
  • Heavy Atom Count: 23
  • Rotatable Bond Count: 2
  • Complexity: 433
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 2
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.5
  • Topological Polar Surface Area: 96.2?2

Experimental Properties

  • Color/Form: Powder
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 616.8±55.0 °C at 760 mmHg
  • Flash Point: 231.5±25.0 °C
  • PSA: 96.22000
  • LogP: 2.09210
  • Vapor Pressure: 0.0±1.9 mmHg at 25°C

6-Methyl-7-O-methylaromadendrin Security Information

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6-Methyl-7-O-methylaromadendrin Related Literature

Additional information on 6-Methyl-7-O-methylaromadendrin

Professional Introduction to Compound with CAS No. 852385-13-8 and Product Name: 6-Methyl-7-O-methylaromadendrin

The compound with the CAS number 852385-13-8 and the product name 6-Methyl-7-O-methylaromadendrin represents a significant advancement in the field of natural product chemistry and pharmaceutical research. This compound, belonging to the lignan class, has garnered considerable attention due to its unique structural properties and promising biological activities. The chemical structure of 6-Methyl-7-O-methylaromadendrin features a complex framework of aromatic rings and methoxy substituents, which contribute to its distinctive chemical profile and potential therapeutic applications.

Recent studies have highlighted the importance of lignans as bioactive molecules with diverse pharmacological effects. Lignans, which are secondary metabolites found in various plants, have been extensively studied for their antioxidant, anti-inflammatory, and anticancer properties. Among these, 6-Methyl-7-O-methylaromadendrin stands out due to its structural complexity and novel derivatives that exhibit enhanced biological activity. The methoxy group at the 7-position in the molecule plays a crucial role in modulating its interactions with biological targets, making it a valuable scaffold for drug discovery.

In the realm of pharmaceutical research, the synthesis and characterization of 6-Methyl-7-O-methylaromadendrin have opened new avenues for developing targeted therapies. The compound’s ability to interact with specific enzymes and receptors has been explored in preclinical studies, revealing its potential as an anti-inflammatory agent. Furthermore, its structural similarity to other lignans that have shown efficacy in treating chronic diseases suggests that 6-Methyl-7-O-methylaromadendrin may have similar therapeutic benefits.

The chemical synthesis of 6-Methyl-7-O-methylaromadendrin has been a subject of interest for organic chemists due to its intricate structure. Researchers have developed novel synthetic pathways that allow for the efficient production of this compound in high purity. These advancements in synthetic methodology not only facilitate further research but also open possibilities for large-scale production for clinical trials and commercial applications. The use of modern techniques such as asymmetric synthesis has enabled the production of enantiomerically pure forms of 6-Methyl-7-O-methylaromadendrin, which is crucial for evaluating its pharmacological properties accurately.

One of the most compelling aspects of 6-Methyl-7-O-methylaromadendrin is its potential as a lead compound for drug development. Its unique chemical structure provides a foundation for designing derivatives with improved pharmacokinetic properties and enhanced target specificity. Researchers are exploring various modifications to the molecule, including changes to the methoxy substituents and other functional groups, to optimize its biological activity. These efforts are part of a broader trend in medicinal chemistry where natural products are being repurposed or modified to develop new drugs.

The biological activity of 6-Methyl-7-O-methylaromadendrin has been investigated in several preclinical models. Studies have shown that it exhibits potent anti-inflammatory effects by inhibiting key pro-inflammatory cytokines and enzymes. Additionally, preliminary data suggest that it may have chemopreventive properties by modulating signaling pathways involved in cancer cell growth and survival. These findings make 6-Methyl-7-O-methylaromadendrin an attractive candidate for further clinical development, particularly in conditions where inflammation and oxidative stress play a significant role.

The safety profile of 6-Methyl-7-O-methylaromadendrin is another critical aspect that has been addressed in recent research. Toxicological studies have been conducted to assess its acute and chronic toxicity, providing valuable insights into its potential side effects. The results indicate that the compound is well-tolerated at doses relevant to therapeutic use, suggesting a favorable safety profile. However, further studies are needed to fully characterize its long-term effects and potential interactions with other medications.

The future directions for research on 6-Methyl-7-O-methylaromadendrin include exploring its mechanisms of action in greater detail. Understanding how this compound interacts with biological targets at the molecular level will provide critical insights into its therapeutic potential and help guide the development of more effective derivatives. Additionally, researchers are investigating ways to improve its bioavailability by formulating it into novel drug delivery systems. These efforts aim to enhance the compound’s efficacy and make it more suitable for clinical use.

In conclusion, 6-Methyl-7-O-methylaromadendrin (CAS No. 852385-13-8) represents a promising natural product with significant potential in pharmaceutical research. Its unique chemical structure, coupled with promising biological activities, makes it an attractive candidate for further development into new therapies. As research continues to uncover more about its properties and potential applications, this compound is poised to play a vital role in addressing various health challenges.

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