Cas no 852-19-7 (4-amino-N-(3-methyl-1-phenyl-1H-pyrazol-5-yl)benzene-1-sulfonamide)

4-Amino-N-(3-methyl-1-phenyl-1H-pyrazol-5-yl)benzene-1-sulfonamide is a sulfonamide derivative characterized by its pyrazole and benzene sulfonamide functional groups. This compound exhibits potential as an intermediate in pharmaceutical synthesis, particularly in the development of antimicrobial or anti-inflammatory agents due to its structural similarity to biologically active sulfonamides. Its well-defined molecular structure allows for precise modifications, enhancing its utility in medicinal chemistry research. The presence of both amino and sulfonamide groups provides reactive sites for further functionalization, making it a versatile building block for drug discovery. High purity and stability under standard conditions ensure reliable performance in synthetic applications.

4-amino-N-(3-methyl-1-phenyl-1H-pyrazol-5-yl)benzene-1-sulfonamide structure

852-19-7 structure

Product Name:4-amino-N-(3-methyl-1-phenyl-1H-pyrazol-5-yl)benzene-1-sulfonamide

CAS No:852-19-7

MF:C₁₆H₁₆N₄O₂S

MW:328.388841629028

CID:722085

PubChem ID:13326

Update Time:2025-05-28

4-amino-N-(3-methyl-1-phenyl-1H-pyrazol-5-yl)benzene-1-sulfonamide Chemical and Physical Properties

Names and Identifiers

- Benzenesulfonamide,4-amino-N-(3-methyl-1-phenyl-1H-pyrazol-5-yl)-
- 4-amino-N-(5-methyl-2-phenylpyrazol-3-yl)benzenesulfonamide
- SULFAPYRAZOLE
- 4-amino-N-(3-methyl-1-phenyl-1H-pyrazol-5-yl)benzene-1-sulfonamide
- 4-Amino-N-(3-methyl-1-phenyl-1H-pyrazol-5-yl)benzenesulfonamide (ACI)
- Sulfanilamide, N1-(3-methyl-1-phenylpyrazol-5-yl)- (7CI, 8CI)
- 1-Phenyl-3-methyl-5-sulfanilamidopyrazole
- 3-(p-Aminobenzosulfoamido)-2-phenyl-5-methylpyrazole
- 3-Methyl-1-phenyl-5-sulfanilamidopyrazole
- 3-Sulfanilamido-5-methyl-2-phenylpyrazole
- 5-(p-Aminobenzenesulfonamido)-1-phenyl-3-methylpyrazole
- Ciba 18,605-Ba
- N1-(3-Methyl-1-phenylpyrazol-5-yl)sulfanilamide
- Sulfamethylphenazole
- Sulfazamet
- Vesulong
- UNII-K980HZ9QO4
- Q27282121
- SULFAZAMET [MI]
- Sulfapirazol [INN-Spanish]
- Sulfapirazol
- Solfapirazolo
- EINECS 212-707-3
- Sulfazamet (USAN/INN)
- Vesulong vet.
- K980HZ9QO4
- DTXSID30234391
- Sulfamethylphenazole; Sulfapyrazole; Vesulong
- Sulphapyrazole
- 4-Amino-N-(5-methyl-2-phenyl-2H-pyrazol-3-yl)-benzene-13C6-sulfon-amide
- 852-19-7
- SCHEMBL193436
- EN300-18563421
- D05954
- NS00009771
- Sulfapyrazol
- Sulfapyrazolum [INN-Latin]
- Sulfapyrazole [INN]
- 1420043-51-1
- Sulfapyrazolum
- Benzenesulfonamide, 4-amino-N-(3-methyl-1-phenyl-1H-pyrazol-5-yl)-
- Solfapirazolo [DCIT]
- CHEMBL2104908
- Sulfamethylphenazole 100 microg/mL in Acetonitrile
- MTERSQYMYBGZTP-UHFFFAOYSA-N
- Ba 18605
- Sulfazamet [USAN]
- Inchi： 1S/C16H16N4O2S/c1-12-11-16(20(18-12)14-5-3-2-4-6-14)19-23(21,22)15-9-7-13(17)8-10-15/h2-11,19H,17H2,1H3
- InChI Key： MTERSQYMYBGZTP-UHFFFAOYSA-N
- SMILES： O=S(C1C=CC(N)=CC=1)(NC1N(C2C=CC=CC=2)N=C(C)C=1)=O

Computed Properties

Exact Mass: 328.099
Monoisotopic Mass: 328.099
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 5
Heavy Atom Count: 23
Rotatable Bond Count: 4
Complexity: 479
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
XLogP3: 1.9
Topological Polar Surface Area: 98.4A^2

Experimental Properties

Density: 1.36
Melting Point: 195° (Seydel, Krueger-Theimer); mp 181-182° (GB 848627)
Boiling Point: 544.5 ℃ at 760mmHg
Flash Point: 283.1 ℃
Refractive Index: 1.671
pka: 5.69(at 25℃)

4-amino-N-(3-methyl-1-phenyl-1H-pyrazol-5-yl)benzene-1-sulfonamide Pricemore >>

Related Categories	No.	Product Name	Cas No.	Purity	Specification	Price	update time
Enamine	EN300-18563421-1g	4-amino-N-(3-methyl-1-phenyl-1H-pyrazol-5-yl)benzene-1-sulfonamide	852-19-7	95%	1g	$842.0	2023-09-18
Enamine	EN300-18563421-5g	4-amino-N-(3-methyl-1-phenyl-1H-pyrazol-5-yl)benzene-1-sulfonamide	852-19-7	95%	5g	$2443.0	2023-09-18
Enamine	EN300-18563421-10g	4-amino-N-(3-methyl-1-phenyl-1H-pyrazol-5-yl)benzene-1-sulfonamide	852-19-7	95%	10g	$3622.0	2023-09-18
Biosynth	AAA85219-5 mg	Sulfamethylphenazole	852-19-7		5mg	$105.00	2023-01-05
Biosynth	AAA85219-10 mg	Sulfamethylphenazole	852-19-7		10mg	$168.00	2023-01-05
Biosynth	AAA85219-25 mg	Sulfamethylphenazole	852-19-7		25mg	$315.00	2023-01-05
Biosynth	AAA85219-50 mg	Sulfamethylphenazole	852-19-7		50mg	$504.00	2023-01-05
Biosynth	AAA85219-100 mg	Sulfamethylphenazole	852-19-7		100MG	$806.00	2023-01-05
Enamine	EN300-18563421-0.05g	4-amino-N-(3-methyl-1-phenyl-1H-pyrazol-5-yl)benzene-1-sulfonamide	852-19-7	95%	0.05g	$197.0	2023-09-18
Enamine	EN300-18563421-0.1g	4-amino-N-(3-methyl-1-phenyl-1H-pyrazol-5-yl)benzene-1-sulfonamide	852-19-7	95%	0.1g	$293.0	2023-09-18

4-amino-N-(3-methyl-1-phenyl-1H-pyrazol-5-yl)benzene-1-sulfonamide Production Method

Production Method 1

907-75-5

852-19-7

Reaction Conditions

1.1 Reagents: Sodium hydroxide Solvents: Water ; 2 h, rt → reflux
1.2 Reagents: Hydrochloric acid Solvents: Water ; pH 5

Reference

The optimization and characterization of functionalized sulfonamides derived from sulfaphenazole against Mycobacterium tuberculosis with reduced CYP 2C9 inhibition

Chen, Hui; Wang, Bin; Li, Peng; Yan, Hong; Li, Gang; et al, Bioorganic & Medicinal Chemistry Letters, 2021, 40,

4-amino-N-(3-methyl-1-phenyl-1H-pyrazol-5-yl)benzene-1-sulfonamide Raw materials

N-[4-[[(3-Methyl-1-phenyl-1H-pyrazol-5-yl)amino]sulfonyl]phenyl]acetamide

4-amino-N-(3-methyl-1-phenyl-1H-pyrazol-5-yl)benzene-1-sulfonamide Preparation Products

4-amino-N-(3-methyl-1-phenyl-1H-pyrazol-5-yl)benzene-1-sulfonamide (852-19-7)

4-amino-N-(3-methyl-1-phenyl-1H-pyrazol-5-yl)benzene-1-sulfonamide Suppliers

Tiancheng Chemical (Jiangsu) Co., Ltd

Gold Member

Audited Supplier

(CAS:852-19-7)Sulfapyrazole

Order Number:LE14136

Stock Status:in Stock

Quantity:25KG,200KG,1000KG

Purity:99%

Pricing Information Last Updated:Friday, 20 June 2025 12:10

Price ($):discuss personally

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