Production Method 1

851386-32-8

851386-33-9

Reaction Conditions

1.1 Reagents: Ammonium formate Catalysts: Palladium Solvents: Ethanol ;  2 h, 25 °C
1.2 Reagents: Hydrochloric acid Solvents: Water ;  acidified, rt

Reference

Selective Functionalization of 2-Fluoropyridine, 2,3-Difluoropyridine, and 2,5-Difluoropyridine at Each Vacant Position

Bobbio, Carla; Schlosser, Manfred, Journal of Organic Chemistry, 2005, 70(8), 3039-3045

5,6-difluoropyridine-3-carboxylic acid Raw materials

• 4-chloro-5,6-difluoro-pyridine-3-carboxylic acid

5,6-difluoropyridine-3-carboxylic acid Preparation Products

• 5,6-difluoropyridine-3-carboxylic acid (851386-33-9)

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• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridines and derivatives Pyridinecarboxylic acids
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridines and derivatives Pyridinecarboxylic acids and derivatives Pyridinecarboxylic acids

• 402-66-4(5-fluoropyridine-3-carboxylic acid)
• 851386-32-8(4-chloro-5,6-difluoro-pyridine-3-carboxylic acid)
• 403-45-2(6-fluoropyridine-3-carboxylic acid)
• 773109-19-6(3-Pyridinecarboxylicacid, 2,5,6-trifluoro-)
• 851386-43-1(2,5-difluoropyridine-3-carboxylic acid)
• 675602-91-2(2,3,5-Trifluoropyridine-4-carboxylic acid)
• 675602-92-3(2,3,6-Trifluoroisonicotinic Acid)
• 851386-31-7(2,3-difluoropyridine-4-carboxylic acid)
• 2875-10-7(tetrafluoropyridine-4-carboxylic acid)
• 944582-95-0(2-Fluoro-4-methylpyridine-5-carboxylic acid)