Production Method 1

75853-20-2

85117-99-3

Reaction Conditions

1.1 Reagents: Hydrogen bromide Solvents: Acetic acid ;  2.5 h, rt → 55 °C

Reference

Synthesis and antimicrobial evaluation of some novel hydrazone derivatives of 2,5-Difluorobenzoic acid

Narisetty, Rajasekhar; Chandrasekhar, K. B.; Mohanty, Sandeep; Rao, M. Rameswara; Balram, B., Journal of Applicable Chemistry (Lumami, 2013, 2(6), 1489-1498

Production Method 2

2646-90-4

85117-99-3

Reaction Conditions

1.1 Reagents: Sodium borohydride Solvents: Methanol ;  1 h, rt
1.2 Reagents: Water
1.3 Reagents: N-Bromosuccinimide ,  Triphenylphosphine Solvents: Tetrahydrofuran ;  45 min, 0 °C → rt
1.4 Reagents: Sodium thiosulfate

Reference

Base-promoted tandem synthesis of 2-azaaryl indoline

Chen, Shuguang; Tan, Jiahong; Wu, Hao; Zhao, Quansheng; Shang, Yongjia, Organic & Biomolecular Chemistry, 2023, 21(46), 9133-9137

2,5-Difluorobenzyl bromide Raw materials

• 2,5-Difluorobenzaldehyde
• (2,5-difluorophenyl)methanol

2,5-Difluorobenzyl bromide Preparation Products

• 2,5-Difluorobenzyl bromide (85117-99-3)

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• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzyl halides Benzyl bromides
• Solvents and Organic Chemicals Organic Compounds Organic Halides

• 23915-07-3(2,4-Difluorobenzyl bromide)
• 113211-94-2(1-(bromomethyl)-2,3-difluorobenzene)
• 151412-12-3(2-Fluoro-3-methylbenzyl bromide)
• 118745-63-4(2-FLUORO-4-METHYLBENZYL BROMIDE)
• 151411-98-2(2,4,6-Trifluorobenzyl Bromide)
• 261763-43-3(2,3-Difluoro-4-methylbenzyl bromide)
• 446-48-0(1-(bromomethyl)-2-fluorobenzene)
• 85118-00-9(2,6-Difluorobenzyl bromide)
• 261951-70-6(4-Fluoro-3-methylbenzyl bromide)
• 886500-09-0(2-Fluoro-5-methylbenzyl bromide)